It generally takes 10 to 12 years for a new drug to hit the market. The pharmaceutical industry invests huge sums in these early stages of research and development. In spite of the rapidly rising research and development expenditures fewer and fewer blockbuster drugs are being developed. Longer lead times and aggressive generic post-patent competition have narrowed the timeframe for the pharmaceutical companies to profit on their investments.In the face of these threats the pharmaceutical industry has developed a battery of strategies to prolong market exclusivity and to maximize return on investment. These emerging strategies are commonly known as Life cycle management (LCM), which actually is more of a concept than a method.

SammanfattningBakgrund: Demens drabbar främst äldre och är en sjukdom där delar av hjärnan avvecklas. Personer med demenssjukdom får en nedsatt kognitiv förmåga och har svårt att minnas saker och utföra vardagliga aktiviteter. Många lider av ätsvårigheter vilket ökar risken för undernäring.Syfte:Att beskriva omvårdnadsåtgärder för att främja näringsintag hos personer med demenssjukdom.Metod: Studien är en litteraturstudie där sökningar i databaserna CINAHL,  PubMed och SweMed+  gjordes för att besvara syftet . Omvårdnadsåtgärder i artiklarna identifierades och kunde sorteras under olika kategorier och subkategorier.Resultat: För att främja näringsintaget hos personer med demenssjukdom identifierades fyra huvudsakliga åtgärder. De som lyftes fram var måltidssituation och matning, näringstillskott, miljöåtgärder och pedagogiska åtgärder.Slutsatser: Resultatet visar att vårdpersonalen har en viktig roll för att främja patienternas näringsstatus och kan tillgodose en gemytlig måltidsmiljö samt näringsrik och allsidig kost.

This essay examines the olfactory reading as a possible way to make sense of a fragmented novel, in this case Sara Stridsberg?s debut Happy Sally (2004). Through close reading, the essay identifies the source of the smells, who perceives it, and how this is portrayed in the text. The smell?s position in the text is understood in relation to Maurice Merleau-Ponty?s phenomenology, where the body, as created in the literary text, is considered as a source of knowledge.

This masters thesis is a gender study of the role of the artist in childrens literature of art. The study comprises forty-three childrens books presenting the life of a historic, contemporary or fictional artist. The books are published from the 1960s to the present day. They are written or translated into Swedish and available in Swedish libraries. The representation of the artist is examined separately in the text and in the illustrations.

There are an increasing number of pupils leaving school with incomplete grades. Research indicates that the causes to this phenomenon may be individual- as well as school related and complicated to illuminate. The purpose of the study is to examine the processes of exclusion that have resulted in pupils´ incomplete degrees. Two research problems have been formulated. The first one is about the identification of exclusion and branding factors for pupils with incomplete degrees.

The study emanates from the national quality registry for persons with severe and profound hearing impairment. The aim was to examine possible differences between signing deaf and adults with acquired severe hearing loss, with reference to self-assessed problems, how the hearing loss influences daily life.In total 234 adults aged 30-90 years were included (128 women, 106 men). In the registry, there are background variables and questions that the patients have answered. The results, indicated on a visual analogue scale (VAS) from 0-100, from a question ?To which extent does your hearing loss at present influence your life?? were analysed.The study was performed by pooling the results of VAS and dividing the patients into signing deaf and those with acquired severe hearing loss, and in age groups 30-60 and 61-90 years.

Titel: Human being and Christian ? creationtheology of Gustaf Wingren.Analysis of an accentshift from a juridical theological metaphor to a biological theological metaphor.Author: Tove Pilroth.The purpose of the essay is to analyse the meaning and the consequences, in a critical and constructive way, of an accentshift of interpretation and understanding of the gospel, from a juridical theological metaphor to a biological theological metaphor. The purpose is presented in the frame of the creationtheology of Wingren. To be able to make the research and to answer the purpose of the essay, the following questions are essential:The human being is captive and redemption is liberation. If we are serious about that the gospel gives the human being rehabilitation, satisfaction, liberation and a life and a future with God, the essential question is which metaphor, a juridical or a biological, that speaks to the human being in the best way? What is the meaning of an accentshift from a juridical to a biological metaphor? How does the creationtheologhy of Wingren, from a biological metaphor, meets the situation of the existence for the human being, her longing for life, health and meaning? What kind of theological resources are present in the creationtheology of Wingren, in the confrontation with future theological challenges?The essay is stressing the need of pluralism in the interpretation of the gospel.

Background: When a child gets cancer it involves the whole family. The view of family focused care has change over the years. It has been shown that the family needs support to manage their life situation, when their child is ill. Aim: The aim of this study was to illustrate the family?s life situation, when a child gets cancer.

Concurrently with higher demands on comparability between companies, all Swedish listed parent companies are guilty to apply international accounting standards, IFRS/IAS, no later than January 1, 2005. In this thesis IFRS 7 Financial instruments: Disclosures, that treats information about financial instruments, is investigated. IFRS 7 aims to establish a good international standard for disclosures about financial instruments. The purpose of this thesis is to study differences in the interpretation of IFRS 7 Financial instruments: Disclosures between Swedish life insurance companies, problems ? if any ? that associate with the recommendation, the recommendation?s effect on accounting and the attitudes towards IFRS amongst the Swedish life insurance companies.

The purpose of this study was to examine the resources and barriers that social workers have incorporating the Social Service Act states during meetings with clients, using and developing the client's skills and knowledge, develop their own resources and to promote the use of self-determination. A qualitative study was done by interviewing six social workers working within the in social service?s department for family and individual welfare. Social workers were encouraged to describe and discuss the key aspects of cases that developed positively respectively negatively. Motivation theory, evidence-based practice, empowerment, and expert-expert relationship are the theories and concepts that we used to analyze the material.The study's main conclusion is that the most important prerequisite for positive development of cases is that the social worker emphasizes and stimulates the client's own resources during meetings.

Over the last decade the conversation on entrepreneurship has been both worldwide and intense. In Sweden, as in many other countries, this conversation has also concerned women?s entrepreneurship. Parallel with this conversation has been the debate on women in leading position in large corporations. This thesis aims to find out why and how women use entrepreneurship to handle existing conditions in life (such as the hardship of combining a traditional career with a traditional family life) and to create new conditions that suit them better.

The purpose of the following essay has been to identify four men?s momentums of their volunteer access to treatment for their disruptive gender-based violence. The questions that have been asked in the entrance of this field have been divided into the following questions: (i) is it possible to identify the processes of change that leads to turning points into the interviewed men's treatment of violence, (ii) how do the interviewed men, themselves, reflect on their turning points into treatment, and (iii) are there other, implicit, interpretations and analyzes of men's access into treatment that I can discern in their stories? As a point of departure of the analysis one theoretical perspective has been used to explain and analyze men?s access to treatment, the sociological life course perspective, focusing on the concept of turning points.The method to approach this field has been qualitative interviews with a Life story oriented approach which means that, focus has been to let the four interviewed men describe their lives from early childhood to their adulthood and from their histories identify contingent processes to their access of treatment. The study resulted in a division of two parts, one part consisting the processes that have been identified by the men?s stories of present tense of violent outbursts.

The purpose of this master thesis is to examine how the relationship between humans and nature is expressed in the imaginative literature. My aim is to identify ideological reproductions in the analyzed works. Therefore I have chosen one work from late 19th century and one from late 20th century. This makes it possible to examine the contextual anchorage of the found ideological expressions. The study?s theoretical framework is primarily based on ecocriticism, and especially on Greg Garrard?s and Kate Soper?s thoughts.

The aim of this study was to examine former criminals? experiences of help and support of importance to leave a criminal life style. The study consists of six interviews with former criminals and earlier studies on the subject. These studies show that relapse in crime are most common among those who are socially excluded from society. They also show that important factors to end a life in criminality are for example a supportive social network.

This study is based on interviews with heads of unit, care staff and senior representatives from a total of six people. We have in this study directed our focus on care quality in the elderly as a concept in development. It appears, when the elderly do not have any dependents, it is even more important that staff supports some extra where no relatives are involved.Quality of life is the broader concept of good quality care and where a good quality of care is a necessary condition for a good quality of life. According to the social services care is the target that older people will live a good life and be allowed to live in a safe environment, which we intend to investigate in this study. Opportunity for greater influence should now be given to older people and their families on how interventions should be designed and implemented.