Determination of serum thymidine kinase 1 (TK-1) activity is used as a tumour marker in both human and veterinary medicine. TK-1 is an intracellular enzyme involved in a salvage pathway of DNA synthesis. The expression of TK-1 is cell cycle dependent and the activity increases markedly after the G1 to S transition in the cell cycle and then declines rapidly in G2. The pronounced proliferative activity in tumour cells result in a higher TK-1 enzyme activity within the cell. The fact that the increased TK-1 activity can be measured in serum makes TK-1 a useful marker in diagnostics of neoplastic diseases and it provides information regarding prognosis and treatment effectiveness. In human medicine a radioactive based test is used to determine the TK-1 serum activity.

AbstractTitle: The old generation and the New World - A qualitative content analysis of media usage of the older generationKeywords:Digital natives, digital immigrants, diffusion of innovation, content analysisThis study has its focus on how the older generation looks at today's media society and the use of today's media. Through a method of qualitative content analysis based on questionnaires, the aim is to examine what the older generation thinks about today's media, how they use them, and whether there are differences in groups according to age and previous work.The study selected theories bases on Marc Prenskys idea of ??digital natives, digital immigrants and Everett M Rogers book on "Diffusion of Innovation". These theories take up the difference on digital natives and digital immigrants and the spread of new technological ideas takes place through communication over different channels in time among causes people in a social system.The result of the study shows that many older people are good at making use of today's media, but also that many may feel alienation of today's media society. Development has proceeded rapidly in recent years and for the older generation it's sometimes hard to keep up.The conclusion of the study is that the older generation may need more help to discover how today's media can facilitate everyday life and enrich it with more communication despite the fact that it takes place through a screen..

Fiscal policy and its consequences have attracted much attention on both academic and societal level, in Sweden and elsewhere. However, the dependence between fiscal policy on municipality level and business cycles has only recently sparked a debate among Swedish economists. Studies point out that a law which came to force in 2000, balanskravet, may have caused municipalities to lower expenditures, alternatively raising taxes, during recessions. This thesis examines how the level of municipality taxes depends on business cycle fluctuations and the impact that balanskravet has had on this correlation. We employ econometric regressions, with annual data covering the period 1980-2014, to enable an analysis of the dependence between taxes and business cycles, both before and after the introduction of balanskravet.

A one-cylinder research engine has been used for studies with a Diesel Dual Fuel concept (DDF). DDF is a concept that utilizes a pilot diesel injection to ignite a homogenous natural gas/air mixture. Emissions and engine efficiency have been analyzed in an emission cycle called European Stationary Cycle (ESC) and the knock/pre-ignition problems with this type of engine have been investigated.At low and mid torque levels, an early diesel injection around 60 crank angles degrees (CAD) before top dead center (TDC) was used. At these loads raw NOxemissions was below EURO 6 level (0.2 g/kWh). NOxwas at EURO 5 level over the complete ESC without after treatment and with SCR at high loads it should be possible to reach EURO 6.One issue with DDF is the high HC emission levels.

Background:Chronic heart failure (CHF) is a complex clinical condition. The higher survival rate after heart attack and other heart diseases, plus aging population, has led to more CHF patients. Symptoms can have negative impact on exercise capacity, ability to perform activities of daily living and quality of life. Heart failure clinics have been established to help better quality of life. Helping to stabilize and maintain patients´ health can reduce the need of hospital admission.

The objective of this M. Eng. Diploma work was to validate the new version, CASMO-5M, and compare the results with CASMO-4E, by using the same input in both programs. The tasks that were included in this work was to compare TIP-measures, k-effective curves (warm), k-effective curves (cold), the effect of void on k-effective, the isothermal temperature coefficient (ITC), the moderator temperature coefficient (MTC), damping ratio calculations, internal effect in a fuel bundle of a BA-rod, the speed of BA-out burn, impact of xenon, falling control rod, margins and isotopes.The TIP-measures showed that the differences were small for all reactors, at most, 6% nodal improvement by C5M (Casmo-5M) for Oskarshamn 3. The warm measurements of k-effective showed that C5M had a higher value for all cycles of Oskarshamn 1, 2 and 3 in comparison to C4E (Casmo-4E).

The primary purpose of this paper is to find the determinants of first-day returns on the Stockholm Stock Exchange. Our research will cover the 1996 ? 2004 periods. Our secondary purpose is intended to find a profitable trading strategy with regard to future IPOs on the Stockholm Stock Exchange. By using regression analysis, focusing on company specific factors and the IPO process, we hope to find a function exhibiting statistical significance, determining future first-day returns from which construction of a profitable trading strategy will be possible.

Det här är en undersökning om holländares val att flytta till Värmland och att starta eget företag sett utifrån ett work-life balance perspektiv. De teorier som har använts är främst work-life balance teorin men även teorier som behandlar flexibilitet, arbete och att starta eget företag återfinns. Inom work-life balance går jag igenom hur olika typer av förändringar i samhället har påverkat och påverkar balansen mellan arbete och fritid. Det tas även upp olika typer av beslut och gensvar som individen kan ta och göra för att motverka obalansen, men dessa individuella beslut är på något sätt relaterade till andra, som till exempel, kommunens gensvar.Jag har använt mig av kvalitativ metod där jag intervjuat nio respondenter i min undersökning. I analys och resultat kapitlet redogör jag för mina upptäckter utifrån den analys jag gjort av mina respondenters berättelser och kopplar det till de teorier jag använt mig av.

The milk production per cow has increased considerably during the last 50 years and due to the breeding for higher milk production also brings decreased reproduction efficiency. In a Swedish study 1996 it was shown that on average only half of all estruses were detected. Every time a farmer fails to detect oestrus it costs the farmer about 1200 Swedish crones and the need of means of detecting oestrus is therofore large. With this study we wanted to investigate if heart rate respectively crystallisation of vaginal mucus (arborisation) could be useful means of detecting oestrus. We monitored two oestrus cycles in four heifers.

To increase the understanding of how individuals total life situation affects their stress level and health has lately more frequently been discussed in different contexts. Furthermore, it is important to have knowledge of power structures that exist under given circumstances in a society to get an increased understanding of how to structure the health promoting work to get the highest possible benefits. People?s work life is essential to their health, since we spend a lot of time at work. The aim of this study was to find out which factors that relate to nursing staff?s health and stress level from a general perspective.

Background: Patients with heart failure is a patient group growing in numbers, the most common treatment focuses on reliving symptoms and the only cure is heart transplantation. Objective: Aim of the study was to illuminate patients' experiences of living with heart failure at his home. Method: Qualitative design, with a manifest content analysis. The results are based on 12 scientific articles.  Results: Patients with heart failure find that the disease is limited to their daily lives through mental illness and physical symptoms.

There are several possibilities for those with an eating disorder, who wishes to get treatment and recover to get help and support. But for those who are not ready to recover, there are not any help to receive. Pro-ana is a youth culture where individuals who want to achieve the anorectic ideal help and support each other. The purpose of this study was to describe and analyse the content and the need for the Pro-ana community on Internet, among young people with eating disorders. More specifically the aim was to find out how young Swedish people uses the Pro-ana communities on Internet.

The goal with our research has been to describe how often and in what way female athletes are represented in the sport section in Sweden?s biggest evening newspaper Aftonbladet. The material we?ve used are the newspapers that we collected during two weeks in 2008, the 3rd of November to the 9th of November and the 11th of November to the 17th of November. We?ve conduced two qualitative researches ? a text analysis and an image analysis ? and one quantitative analysis on our material.

När Sydafrika blev en demokrati 1994 gjordes utbildningssystemet om. En del i de storaförändringarna var att introducera Life Orientation, ett nytt ämne från och med 1998.Forskning har visat att införandet av ämnet inte varit friktionsfritt, vilket bland annat berott påatt ämnet varit nytt och det varit brist på lärare med relevant utbildning för att undervisa i LifeOrientation.Syftet med den studie som gjorts var att ta reda på hur lärare på en High School (årskurs 8-12)upplever idrottsämnets ställning är på deras skola, mot bakgrunden att ämnet integrerats i LifeOrientation som ett av sex delområden. En kvalitativ forskning har genomförts medsemistrukturerade interjuver som metod. Resultatet i undersökningen visade utifrån de trefrågeställningsparametrarna; uppfattningar om ämnet, upplevelser av ämnet och åsikter om demateriella förutsättningarna, att lärarna upplevde att ämnets ställning var låg på deras skola.Nyckelord: Sydafrika, utbildning, Life Orientation, idrott och hälsa, ställning, status,upplevelser, materiella förutsättningar.

The purpose of this paper is to test a procedure that would be useful for a certain, more final purpose. Assume that you want to know if the differences in the result of a certain effort in health care have any connection with differences between the life situations of the patients. This would be easier to investigate if the life situations of the patients had connection to the easily available variable Health Care Cost (in Swedish VK). In that case the searching for connections between VK of patient groups and the result of health care efforts would be sufficient to gain knowledge of possible connection between health care efforts and life situations. Thus that is the final purpose.