Determination of serum thymidine kinase 1 (TK-1) activity is used as a tumour marker in both human and veterinary medicine. TK-1 is an intracellular enzyme involved in a salvage pathway of DNA synthesis. The expression of TK-1 is cell cycle dependent and the activity increases markedly after the G1 to S transition in the cell cycle and then declines rapidly in G2. The pronounced proliferative activity in tumour cells result in a higher TK-1 enzyme activity within the cell. The fact that the increased TK-1 activity can be measured in serum makes TK-1 a useful marker in diagnostics of neoplastic diseases and it provides information regarding prognosis and treatment effectiveness. In human medicine a radioactive based test is used to determine the TK-1 serum activity.

The health care system in most western countries is undergoing rapid changes with an increasing amount of people living with chronic cancer. These people have to deal with their disease in every day life together with working and family life. The relationship between health services and every day life has changed and raises new requirements. Earlier research has shown that maintaining every day life is important for cancer patients and their families. This study comprised patients with lymphoma receiving their diagnosis during 2003 ? 2005.

I följande studie kommer rekryterings- och utvecklingsmetoden Assessment Center (AC) attstuderas. Syftet med studien är att utifrån verksamma organisationers erfarenhet av AC skapa en ökad förståelse för; metodens innebörd, vilka argument som ligger till grund förorganisationers användande av metoden samt dess värde för organisationer. Studien är avkvalitativ karaktär och fokus fästs vid tolkning och förståelse av AC baserat pårespondenternas subjektiva uppfattningar och upplevelser. Studiens teoretiska referensrambehandlar; Human Resource Management, rekrytering, personalekonomi, Talent Management och Assessment Center. Empiri har samlats från sex verksamma organisationer, varav fem organisationer vilka arbetar med AC samt en organisation som har påvisat ett eventuellt intresse av att utveckla ett AC.

A one-cylinder research engine has been used for studies with a Diesel Dual Fuel concept (DDF). DDF is a concept that utilizes a pilot diesel injection to ignite a homogenous natural gas/air mixture. Emissions and engine efficiency have been analyzed in an emission cycle called European Stationary Cycle (ESC) and the knock/pre-ignition problems with this type of engine have been investigated.At low and mid torque levels, an early diesel injection around 60 crank angles degrees (CAD) before top dead center (TDC) was used. At these loads raw NOxemissions was below EURO 6 level (0.2 g/kWh). NOxwas at EURO 5 level over the complete ESC without after treatment and with SCR at high loads it should be possible to reach EURO 6.One issue with DDF is the high HC emission levels.

När en kommersiell hamn byggs ut fordras omfattande muddringsarbete för att säkerställa ett brukligt djup för sjöfart. Då stora delar av muddermassorna ofta är förorenade av tungmetaller och miljögifter krävs särskilt omhändertagande av dessa. Traditionella omhändertagningsalternativ består av att deponera massorna på särskild avsedd plats på land eller tippa till havs, något som inte tillåts för förorenade sediment. En relativt ny metod är stabilisering/solidifiering (S/S) som innebär att muddermassorna behandlas med ett bindemedel för att sedan kunna användas som fyllnadsmaterial i exempelvis kajkonstruktioner. Dessa alternativ behöver noga vägas mot varandra med hänsyn till ekonomiska och miljömässiga aspekter.

This study has been carried out in the spring of 2014 on behalf of PQR Consult AB in Stockholm. The aim of the study has been to analyse the energy usage of the building Skarpövägen 1 in order to explore the possibilites of saving energy by using appropriate equipment. These possible solutions have been simulated by using the programe IDA Indoor Climate and Energy, combined with a life cycle cost analysis. The laundry building, Skarövägen 23, has also been analysed due to its high amount of energy usage. The result of the energy analysis showed that the energy usage was much higher than the energy declaration.

The real estate industry is a sector where the companies generally have a capital structure which is high leveraged. The financing? with the related terms ? is therefore specifically of high importance for the companies in the sector. Traditionally, the way of obtain financing is by borrowing from the bank. Lately, due to new bank regulations, the banks have become more restrictive in their lending which have lead to a growth of other financing alternatives.

Forensic psyhiatric care protects the society by giving patients care to diminish risks of serious crimes. In their work the nurses use different care methods to help and support the patient in managing his or her life situation. To clarify how a group of nurses describe the nursing process in forensic psychiatric care. A qualitative study based on interviews. Six nurses were interviewed about their work in four different forensic psychiatric care units.

Regardless of what discipline nurses work in, wound care is one of the tasks. Caring for wounds involves early detection of signs of infection, in order to avoid complication. Wound infection extends suffering for the patient and causes unnecessary costs for society. The aim was to describe how nurses can identify infection in wounds. Method: The design of the study was a literature review, where13 scientific articles were examined and analyzed.

The objective of this M. Eng. Diploma work was to validate the new version, CASMO-5M, and compare the results with CASMO-4E, by using the same input in both programs. The tasks that were included in this work was to compare TIP-measures, k-effective curves (warm), k-effective curves (cold), the effect of void on k-effective, the isothermal temperature coefficient (ITC), the moderator temperature coefficient (MTC), damping ratio calculations, internal effect in a fuel bundle of a BA-rod, the speed of BA-out burn, impact of xenon, falling control rod, margins and isotopes.The TIP-measures showed that the differences were small for all reactors, at most, 6% nodal improvement by C5M (Casmo-5M) for Oskarshamn 3. The warm measurements of k-effective showed that C5M had a higher value for all cycles of Oskarshamn 1, 2 and 3 in comparison to C4E (Casmo-4E).

Det här är en undersökning om holländares val att flytta till Värmland och att starta eget företag sett utifrån ett work-life balance perspektiv. De teorier som har använts är främst work-life balance teorin men även teorier som behandlar flexibilitet, arbete och att starta eget företag återfinns. Inom work-life balance går jag igenom hur olika typer av förändringar i samhället har påverkat och påverkar balansen mellan arbete och fritid. Det tas även upp olika typer av beslut och gensvar som individen kan ta och göra för att motverka obalansen, men dessa individuella beslut är på något sätt relaterade till andra, som till exempel, kommunens gensvar.Jag har använt mig av kvalitativ metod där jag intervjuat nio respondenter i min undersökning. I analys och resultat kapitlet redogör jag för mina upptäckter utifrån den analys jag gjort av mina respondenters berättelser och kopplar det till de teorier jag använt mig av.

To increase the understanding of how individuals total life situation affects their stress level and health has lately more frequently been discussed in different contexts. Furthermore, it is important to have knowledge of power structures that exist under given circumstances in a society to get an increased understanding of how to structure the health promoting work to get the highest possible benefits. People?s work life is essential to their health, since we spend a lot of time at work. The aim of this study was to find out which factors that relate to nursing staff?s health and stress level from a general perspective.

Background: One in ten couples suffers from some form of involuntary childlessness or infertility in Sweden. Involuntary childlessness or infertility is when an individual or a couple has a desire for a child but are unable to conceive on their own. To suffer from involuntary childlessness can be a mental strain that can result in a personal crisis, where the existential issues become central and contested. Regardless of the reason for their changed life world is because of involuntary childlessness or infertility, it is always important for the nurse to have an understanding of individual?s life-changing world and experiences. Aim: The aim of the study was to describe men and women experiences of involuntary childlessness during investigation and treatment.Method: Selected method was a literature review. The study was based on articles from systematic and unsystematic searches in databases and analyzed from the chosen method.Results: Four main themes emerged from the analysis, 'The changing life-world', 'The mental strain', 'Perceptions of relationships and social life' and 'experiences related to treatment'.Conclusion: Being involuntarily childless and infertile create a mental, physical and social stress. Clinically, this means a responsibility to offer a personalized support. For the nurse it is important to have an understanding of individual life-world and how the involuntary childlessness affects them. .

The real estate industry is a sector where the companies generally have a capital structure which is high leveraged. The financing? with the related terms ? is therefore specifically of high importance for the companies in the sector. Traditionally, the way of obtain financing is by borrowing from the bank. Lately, due to new bank regulations, the banks have become more restrictive in their lending which have lead to a growth of other financing alternatives.

This thesis compares different methods for risk assessment of a creosote contaminated site in Vansbro, Dalarna. In a complementary study the importance of using representative data for calibration and validation of stationary groundwater models is discussed. The time dependency between surface water levels and groundwater levels on the site in Vansbro is evaluated by step response analysis. The results show that the groundwater levels reflect only long-term variation in the surface water levels. Hence the use of such long-term means for calibration and validation of the stationary groundwater models is the only theoretically defendable alternative.As a first step in the comparison of risk assessment methods the degree of contamination is evaluated on the basis of generic guideline values for contaminated soils, developed by the Swedish Environmental Protection Agency.