Amyotrophic lateral sclerosis is one of the major neurodegenerative diseases, causing an ascending paralysis that usually kills the patient within a few years from disease onset. The motor neurons show aggregates of proteins which in approximately 20 % of cases of the familial form contain mutated SOD1 protein. Trehalose is a disaccharide which has been shown to reduce protein aggregation and increase viability in cell models and alleviate symptoms in animal models of several neurodegenerative diseases associated with protein aggregation. When given orally to the SOD1G93A mouse model of ALS, trehalose failed to slow down the disease progression, which has led to questions about the uptake and distribution of the molecule in this mouse strain. The aim of this study was to investigate whether significant levels of trehalose reach the central nervous system of the SOD1G93A mouse after oral administration. This was performed by a trehalose assay of the brain of trehalose treated animals. A glucose assay was optimised for use in small samples of brain lysate after the digestion of trehalose into glucose by trehalase, and the difference in glucose concentration before and after digestion represented the trehalose level.

The objective of this study was to study the agreement between two methods of indirect bloodpressure measurement in dogs and cats and to establish the within-method variation for the methods. The utility and practicality in the clinical setting were also evaluated for the both methods. The techniques evaluated were the oscillometric method and the Doppler ultrasonographic method. Thirtytwo dogs and 26 cats were used in the study and seven dogs and five cats out of these animals had diseases that may effect the bloodpressure. Bloodpressure was measured in both anesthetized and in conscious animals.

Multiple factors are involved in control of beef sensory quality so great variation can be induced. The perception of meat quality can be affected anywhere in the product chain. Both the environment and the set of genes of the animals have an effect on the final output. A problem facing the beef industry today is the significant variations in meat quality between individual animals, which is reflected in the uneven quality of the meat that reaches the consumer. If the quality of meat in stores varies significantly over time, the consumers? trust may decrease.

Cats and dogs are often unattended by their owners both indoors and outdoors, and therefore there is always a risk that they will get hurt. In the past, poisoning cases was considered unusual, but nowadays they are considered more common. As a veterinary nurse, it is important to know the common symptoms of poisoning, especially when working with emergency veterinary care. A very essential part of the profession as a veterinary nurse is to inform pet owners about the potentially dangerous substances and how poisonings can be prevented. The purpose of this report was to find out what is written scientifically about some common poisonings in dogs and cats and to present available statistics that covers the number of animals poisoned by various substances in Sweden. Hopefully this essay can also be used as a handbook for professionals in animal health care and to assist in educating pet owners. The report mainly covers groceries found in many homes, often easy accessible.

The situation of officials of public and governmental organizations have been recognized as increasingly risky, in which the influences of both threats and violence have become an issue that administrators have to manage. Experiences of feeling threatened in their workplace or in their professional lives has been marked by an increased number of reported cases in the work environment authority. Common to the problems faced by many agencies and important associations that dealt with its often derive personal and sensitive issues. The purpose of this study is to highlight how veterinarians and animal welfare inspectors on the counties of Blekinge, Kronoberg and Kalmar experience the interaction of regulatory and prohibition cases. Länsstyrelsen is the one that can decide what is to happen to an animal that has been kept under bad conditions.

Too many dogs are euthanized because of different kind of behaviour problems today. Is it really necessary? Who has the main responsibility for this action? Do breed differences matter when it comes to increased risk of euthanasia of the dog? The purpose of this piece of work is to find the answers to these questions and also to find out what kind of behaviour problems that can lead to euthanasia of dogs in general. The most common reason for dogs being euthanized is aggression. The aggression can be directed toward humans or other animals, mostly other dogs. There are some important factors of the dog that increases the risk of being euthanized, and these are the breed, the gender and sexual status and also the size of the dog.

The aim with the literature study is to inform about the risks that exists in large dairy farms(with focus on mastitis and hoof health) and to inform about the milk industry in Sweden.Personal comments from two study visits (Nötcenter Viken and Vadsbo Mjölk AB) arelinked together with the literature and forms into a discussion regarding sustainableagriculture versus the milk cow's welfare.The profitability for Sweden's milk farmers have decreased because of the decreased milkprice and current inflation. This leads to an increase in herdsize in order to make a profit.The milk cow herds in Sweden becomes fewer year by year and the herdsize increases. Theincreased herdsize can cause a decrease in the time the farmer spends per animal. This canaffect early disease detection and prolong the animals suffering.Swedish Board of Agriculture published (2008) statistics showing that today's milk cow ismedicated primarily because of two reasons; mastitis or hoof problems. Mastitis is thereason to two thirds of all treatments that are carried out.

The situation of officials of public and governmental organizations have been recognized as increasingly risky, in which the influences of both threats and violence have become an issue that administrators have to manage. Experiences of feeling threatened in their workplace or in their professional lives has been marked by an increased number of reported cases in the work environment authority. Common to the problems faced by many agencies and important associations that dealt with its often derive personal and sensitive issues. The purpose of this study is to highlight how veterinarians and animal welfare inspectors on the counties of Blekinge, Kronoberg and Kalmar experience the interaction of regulatory and prohibition cases. Länsstyrelsen is the one that can decide what is to happen to an animal that has been kept under bad conditions.

The study was carried out at the Kungsängen Research Centre, Department of Animal Nutrition and Management, Swedish University of Agriculture Sciences, Uppsala. The technical development in dairy production has resulted in a housing system where feeding and milking is done automatically without human contact, a so called automatic milking system. The motives for utilising an automatic milking system, is to increase the animal welfare and to decrease the need for manual labour. However, the system does involve a change for the animals, among the effects is the deprival or the diminishment of a chance for synchronous behaviour and the animals have to agree among themselves in which order they use the feeding stations and the milking unit itself. How and if this affects the animals well-being and production is yet to be solved. A possible way to form an opinion on this, is to study the animals ranking order along with hormone profiles and production. The purpose of this work was to study the effect of low- vs.

Today the individual ventilated cage system (IVC-system) is a commonly used housing system for mice in research facilities. IVC systems have HEPA- filters and are designed to control both supply and exhausted air at cage level, as well as temperature and relative humidity in the cages. This creates an optimal environment for the mouse and at the same time a protection against the risk of cross-infection between cages and the outside environment. The aim of this study was to evaluate the health and welfare of breeding females and pups of two different strains of laboratory mice (NMRI nude mice and C57BL/6N) in three different kinds of IVC-systems; Arrowmight, Allentown and Tecniplast. The NMRI nude (Nu) females gave birth to 18 litters in Allentown, 16 litters in Arrowmight and 15 litters in Tecniplast.

Södra Cell Mörrum is one of the five paper pulp plants that are included in Södra Cell, and the paper pulp that is produced here is not only sold to Swedish paper mills. Most of the paper pulp is exported to different countries in Europe. In the manufacturing process the plant needs different kind of process water and there are guideline values for how much copper, iron and sodium this water is allowed to contain. Analyzes of this water is in the current situation done with an atomic absorption spectrometric instrument (AAS-instrument) with a flame. Measurements done with flame-AAS of samples that have concentrations near the guideline values for copper, iron and sodium, are not reliable. The reason for not being reliable is that the quantitation limits of these metals are higher than the limit values.

In Sweden, there has been a continuous increase in the volume of housing construction for dairy cattle. Since 2004, the number of new, rebuilt and extended dairy cow houses undergoing preliminary inspection by the authorities has grown. The livestock farms have mostly focused on cow units instead of calf and heifer sheds; which has led to a need for information in this area. The purpose of the study was to improve advisors? knowledge about bovine building construction and function; to enable them to provide more qualified advice to conventional and organic milk producers who sustain larger herds.

The Swedish wolf population is like continue to grow and this will eventually lead to an increase in the predation of livestock. In Sweden carnivore attacks happen most frequent on sheep farms and the majority of these attacks are performed by wolves. Because of this, the main focus in this study is on the sheep and wolf problematic. It is not only the direct killing of livestock that affects the animals and their owners in a negative way. It has also been shown that livestock that lives close to carnivores sometimes change their behaviour in a way that will affect their ability to reproduce and to forage efficiently.

The central part in all public health work is health promotion and disease preventing actions among the population. Since all public health work includes the whole population, the work has to embrace disabled people as well. Within the disability policies, participation and equality are important goals, which illustrate the importance of a job. In previous studies the positive effects of animal have been detected among persons with disabilities, by better balance, better mobility, larger social network, new knowledge and most of all happiness. The aim of this study was to investigate how people with disabilities experience their health when they are working with animal husbandry at daily activities.

In October 2009, a new decision was made concerning the administration of predators which resulted in a new wolf policy in Sweden. This meant that the wolf population now should be limited to 210 individuals by harvest. The new policy also recognized that the public acceptance of this species must increase and the genetic status improved. In the 17th of December a decision was taken by the Swedish parliament that it should become legal to hunt wolves in Sweden. The wolf hunt resulted in debate on a large scale amongst people, some thought of it as a good decision while others thought it was wrong.