Background:  Heart failure is a multidimensional phenomenon with high mortality. Heart failure is treated with angiotensin converting enzyme (ACE) - inhibitors or angiotensin receptor blockers (ARBs) that counteract neurohormonal stimuli that occur in heart failure, as well as providing vessel dilatation, which reduces symptoms and the need for hospitalization and increases survival. Despite this, only about 50% of heart failure patients survive 6 years after diagnosis with drug therapy, and as heart failure is increasing globally, due to improved care and treatment and increasing life expectancy of the population, there is a great need for new drugs such as LCZ696 that acts by dual inhibition of the renin - angiotensin - aldosterone system and neprilysin inhibition.Objective: The aim of this literature study was to evaluate the efficacy of current treatment and possible future treatments on mortality and morbidity in heart failure patients.Results: The examined articles show that treatment with ACE inhibitors in patients with symptomatic heart failure reduces the risk of total mortality by 16% over 3.5 years, reduces all-cause mortality or hospitalization due to heart failure with NNT (number needed to treat) = 10.4 over 3.5 years and increases median survival by 9.2 months over 12.1 years in patients with asymptomatic heart failure. Treatments with high-dose ACE inhibitors reduce mortality and hospitalization because of cardiovascular causes and hospitalizations from any cause by NNT = 30 over 3 years. Beta-blockers reduce sudden death and total mortality and cardiac death or non - fatal myocardial infarction with NNT = 38 and NNT = 23, respectively, over 12 months.

AbstractPurpose: The purpose of this study was to see if there was any correlation between BMI and chronic pain among participants who underwent a behavioural medicine rehabilitation program at a pain clinic in the central part of Sweden. Method: The study was conducted as a quantitative descriptive study context and has used medical records with documented data from the participants who were part of a pain clinic rehabilitation programs in the years 2004-2005. Altogether there were 76 participants in these years and excluded was nine participants with BMI measurements were not included in the documentation. Main Results: Regarding the relationship between BMI and chronic pain there was no significant relationships. Participants who completed the behavioural medicine rehabilitation program, however, showed a lower value of BMI and the estimated pain in VAS from the first to the third which is the last time of measuring.

Background: Individuals in pain is something that most nurses encounter on a daily basis. Chronic physical pain is often followed by psychological pain. The total effects of chronic pain are felt by the patient as well as by close ones. The findings showed that life changed radically after getting chronic pain. Individuals and closeones both had to take every day as it came, because the degree of pain was hard to predict and could worsen at any time off the day.

AbstractPurpose: The purpose of this study was to see if there was any correlation between BMI and chronic pain among participants who underwent a behavioural medicine rehabilitation program at a pain clinic in the central part of Sweden. Method: The study was conducted as a quantitative descriptive study context and has used medical records with documented data from the participants who were part of a pain clinic rehabilitation programs in the years 2004-2005. Altogether there were 76 participants in these years and excluded was nine participants with BMI measurements were not included in the documentation. Main Results: Regarding the relationship between BMI and chronic pain there was no significant relationships. Participants who completed the behavioural medicine rehabilitation program, however, showed a lower value of BMI and the estimated pain in VAS from the first to the third which is the last time of measuring.

This thesis studies the relationship between risk and the first day returns of Initial Public Offerings (IPO) by assessing the risk of each issuing company with a risk model that combine financial key ratios of importance. The study is based on 92 IPO?s that were made on the Stockholm OMX stock exchange during the period of 1997-2009. The point of departure was to investigate if the uncertainty created by the asymmetric information between investors and the issuing firm could be captured by predicting the possibility of failure in the future. This has been studied by applying Skogsvik?s probability of failure model on the 92 issuing firms.

The purpose of this essay was to review the literature and describe the patophysiology, diagnosis, microscopic and macroscopic appearance of aortic body tumors in dogs. The tumors originate from the chemoreceptor organs situated at the base of the heart. The chemoreceptor organs are neuroendocrine cells responsible for surveillance of changes in e.g. the blood pH. Aortic body tumors are rare and represent 7 % of the total cases of primary cardiac tumors in canines.

Heart failure is a condition where the heart is incapable of providing adequate blood supply to different organs in the body. The underlying causes of heart failure is some kind of disorder in the heart function, and require careful diagnostics. The basic symptoms that arise from heart failure is difficulty in breathing, that aggravate when lying down, and fatigue. The patients? symptoms and impaired quality of life can be in different stages depending on the severity of the heart failure.

This report consists of  an anlysis of the imapct of a dam failure at Tjärnviksdalen in Ragunda, Sweden. The analysis is conducted using the EU model for environmental impact assessments, as well as a group interview. The presentation of the results in the form of a map  where the water level has been raised to the level that the County Board  of Jämtland considers to be possible in case of a dam failure.The result of this work is a detailed analysis of the consequenses that a dam failure would cause, the result consider everything from the direct consequences of the water column to an analysis of the chemical changes that the water would undergo.Parts of the analysis have shown that the purification centre and the old deposits will have the biggest impact on Hammarstrand. Both the purification centre and the deposits will realise chemicals to its nearest environment and because of the flooded purification centre the city will not have the ability to clean the water. .

Hydropericardium or pericardial effusion (PE) is the accumulation of fluid in the pericardial sac and is often secondary to pericardial diseases or diseases related to the heart. It is unusual with clinically relevant pericardial diseases in cats but pericardial effusion is the most common one. Since PE causes serious symptoms and may lead to death it is important with a quick diagnosis and treatment. PE can be acute and cause cardiac tamponade, which gives severe clinical signs. Cardiac tamponade needs to be treated immediately or else the cat will die from cardiogenic chock. More common is chronic PE where the fluid accumulates during a longer period of time and the pericardial sac stretches.

Hydropericardium or pericardial effusion (PE) is the accumulation of fluid in the pericardial sac and is often secondary to pericardial diseases or diseases related to the heart. It is unusual with clinically relevant pericardial diseases in cats but pericardial effusion is the most common one. Since PE causes serious symptoms and may lead to death it is important with a quick diagnosis and treatment. PE can be acute and cause cardiac tamponade, which gives severe clinical signs. Cardiac tamponade needs to be treated immediately or else the cat will die from cardiogenic chock. More common is chronic PE where the fluid accumulates during a longer period of time and the pericardial sac stretches.

Background: Chronic pain is a condition that approximately 18% of the Swedish population suffers from. This condition affects many aspects of a person´s life and causes psychological, physiological and social suffering. Multimodal treatment is considered the most effective treatment for patients with chronic pain. Patient participation and motivation are very important to treatment. Aim: The aim of this study was to explore patients´ experience of a multimodal chronic pain treatment program regarding their experience of patient participation and interaction with the rehabilitation team.

This study aims to examine how adolescents with diabetes describe and value their experience of participating in a support group and how they describe the issues of being a teenager with diabetes. This is a qualitative study and we have interviewed three young women who have been participating in a support group. The results of the interviews were analyzed through a phenomenological method and then compared to earlier research and interpreted through symbolic interactionism and Erikson's development-theory, which were our theories of choice. Our findings support earlier research when stating that support groups are important and necessary for adolescents with chronic illnesses. Our interviewees stated that they think that one of the most important benefits of support groups is to meet other people in their situation; same age and same chronic illness..

Aim: The aim of this study was to highlighting the experiences of individuals of non-pharmacological treatment for chronic pain.Method: The study was designed as a literature review with aim to review andcompile the articles results. This study has been based on a systematic literature search of supplementing out of an unsystematic search were 11 articles were found.Results: The participants in the studies had experienced a good effect out of non-pharmacological treatments for their pain and a improved quality of life. Based on participants´ experiences of treatment two categories occurred: body awareness and relaxation. Body awareness arose through treatments like yoga, mindfulness meditation and CBT. Relaxation occurred through treatments, like music, heat, massage and meditation.Conclusion: This study highlights how non-pharmacological treatments is experienced by individuals with chronic pain and two key areas have been identified.

Both serum creatinine and measuring GFR can be used to evaluate renal function in dogs suspected to have chronic kidney disease (CKD). Although high creatinine levels usually indicate renal disease, normal creatinine levels can be present in dogs with decreased renal filtration. Measuring GFR is generally believed to be the most accurate way of detecting decreased renal filtration and scintigraphy GFR using 99mTc-DTPA has been found to correlate well with the ?gold standard? inulin clearance method.When measuring GFR by scintigraphy, 99mTc-DTPA is injected intravenously and radioactive decay of technetium gives rise to gamma radiation, which is registered by a gamma camera. Pictures and curves of radioactivity in the kidneys are generated by means of a computer program.

Canine otitis externa is a common reason for a visit to the vet. Predisposing factors often complicate treatment and may result in a chronic disease progression. All otic preparation for topical use in Fass Vet contain antibiotics, corticosteroids and a fungicide. Sixty cerumen samples from dogs with external otitis, sent to the Department of Bacteriology at SVA, were categorised according to their profile of isolated microorganisms. Staphylococcus intermedius alone or together with Malassezia pachydermatis were the most common organisms found. Fifteen percent of the samples contained M.