The improvement programme Six Sigma has often been surrounded by an air of success since it was introduced in the 1980s. Yet there are cases in which introduction of the Six Sigma improvement programme show far from successful results, even complete implementation failures with no traces of the Six Sigma methodology or any improvements after completion of the introduction. These failures can cause severe damage to organizations through direct monetary loss caused by a negative result of the investment. Indirectly the failure can cause confusion in the organization and loss of employee motivation. The conclusions have been derived based on a qualitative case study at a Swedish telecommunications company.

Background:  Heart failure is a multidimensional phenomenon with high mortality. Heart failure is treated with angiotensin converting enzyme (ACE) - inhibitors or angiotensin receptor blockers (ARBs) that counteract neurohormonal stimuli that occur in heart failure, as well as providing vessel dilatation, which reduces symptoms and the need for hospitalization and increases survival. Despite this, only about 50% of heart failure patients survive 6 years after diagnosis with drug therapy, and as heart failure is increasing globally, due to improved care and treatment and increasing life expectancy of the population, there is a great need for new drugs such as LCZ696 that acts by dual inhibition of the renin - angiotensin - aldosterone system and neprilysin inhibition.Objective: The aim of this literature study was to evaluate the efficacy of current treatment and possible future treatments on mortality and morbidity in heart failure patients.Results: The examined articles show that treatment with ACE inhibitors in patients with symptomatic heart failure reduces the risk of total mortality by 16% over 3.5 years, reduces all-cause mortality or hospitalization due to heart failure with NNT (number needed to treat) = 10.4 over 3.5 years and increases median survival by 9.2 months over 12.1 years in patients with asymptomatic heart failure. Treatments with high-dose ACE inhibitors reduce mortality and hospitalization because of cardiovascular causes and hospitalizations from any cause by NNT = 30 over 3 years. Beta-blockers reduce sudden death and total mortality and cardiac death or non - fatal myocardial infarction with NNT = 38 and NNT = 23, respectively, over 12 months.

This thesis studies the relationship between risk and the first day returns of Initial Public Offerings (IPO) by assessing the risk of each issuing company with a risk model that combine financial key ratios of importance. The study is based on 92 IPO?s that were made on the Stockholm OMX stock exchange during the period of 1997-2009. The point of departure was to investigate if the uncertainty created by the asymmetric information between investors and the issuing firm could be captured by predicting the possibility of failure in the future. This has been studied by applying Skogsvik?s probability of failure model on the 92 issuing firms.

Heart failure is a condition where the heart is incapable of providing adequate blood supply to different organs in the body. The underlying causes of heart failure is some kind of disorder in the heart function, and require careful diagnostics. The basic symptoms that arise from heart failure is difficulty in breathing, that aggravate when lying down, and fatigue. The patients? symptoms and impaired quality of life can be in different stages depending on the severity of the heart failure.

This report consists of  an anlysis of the imapct of a dam failure at Tjärnviksdalen in Ragunda, Sweden. The analysis is conducted using the EU model for environmental impact assessments, as well as a group interview. The presentation of the results in the form of a map  where the water level has been raised to the level that the County Board  of Jämtland considers to be possible in case of a dam failure.The result of this work is a detailed analysis of the consequenses that a dam failure would cause, the result consider everything from the direct consequences of the water column to an analysis of the chemical changes that the water would undergo.Parts of the analysis have shown that the purification centre and the old deposits will have the biggest impact on Hammarstrand. Both the purification centre and the deposits will realise chemicals to its nearest environment and because of the flooded purification centre the city will not have the ability to clean the water. .

Renal dysplasi (RD) is a congenital chronic renal disease affecting young dogs. It is a rather common disease that occurs in a large number of dogs and in some breeds there is a familiar incidence or suspected hereditary background. Both the etiology and pathogenesis are still unknown, but a theory about the cause of RD is that the two components that form the kidney, the uretheric bud and the metanephrogenic blastema, don´t interact normally in the embryo. Kidneys affected by RD contain fetal (immature) structures that are inappropriate for the state of development/age of the dog and abnormal structures caused by an abnormal differentiation. Affected dogs usually are under .

As the occurrence of obesity increases amongst young people, so increases the risk of more people suffering from heart failure as early as during middle age. The aim is to describe the life experiences of middle aged persons living with chronic heart failure. The literature study is based on twelve published, qualitative, and scientifically proved articles derived from MedLine and Cinahl using queries representing the subject, as well as from manual searching in ScienceDirect and LIBRIS. These articles have been analyzed from a life world perspective. Four main themes and four sub themes were identified from the articles' results.

Abstract Chronic heart failure is a common disease in elderly, and is the most common reason for hospitalization in patients over 65 years of age. Research on the elderly and heart failure often focus on treatment strategies, less research is available on patients' own experiences of living with chronic heart failure. The purpose of this interview study, was to gain more knowledge about patients´ own experiences of living with chronic heart failure. Nine patients were interviewed and the text was transcribed verbatim and it was then analyzed with a phenomenological hermeneutical method. From the analysis, three main themes emerged.

Background:Chronic heart failure (CHF) is a complex clinical condition. The higher survival rate after heart attack and other heart diseases, plus aging population, has led to more CHF patients. Symptoms can have negative impact on exercise capacity, ability to perform activities of daily living and quality of life. Heart failure clinics have been established to help better quality of life. Helping to stabilize and maintain patients´ health can reduce the need of hospital admission.

The aim of this study is to investigate what psyhosocial problems that occur among congestive heart failure patients and what needs for patient education related to self-care that exists within this group. The method is a literature review. The result identifies psyhosocial problems that arise in the daily life of congestive heart failure patients and how these affect their life sitation..

Ultrasound is a diagnostic aid often overlooked by the veterinary practicioner who works with farm-animals. However, it?s use increases, particulary for breeders where ultrasound has long been used to evaluate ovaries and to diagnose pregnancy or disturbances in reproduction. There is much knowledge in how to examine ovaries and uterus by transrectal ultrasound, but when it comes to doing ultrasound of other organs in the abdomen the knowledge is more limited. Cows are very large animals, so it is not possible to examine everything inside the abdomen with ultrasound, simply because the ultrasound beam has a limited penetration. There is also lots of gas inside the gastro-intestinal tract of a cow, mainly in the large intestine and the rumen, and that makes it impossible to examine the organs behind the gas since the ultrasound waves are reflected when reaching the soft tissue-gas interface.

The aim of this small thesis is to investigate if the probability of business failure is higher at the time of divestment than at the time of acquisition for portfolio companies that have been subject to private equity ownership. The background for this thesis is the widespread critique aimed at private equity firms, claiming that they increase the risk in their portfolio companies. We have performed a study of 53 buyout transactions, involving Swedish manufacturing companies, covering a time span of 13 years, from 1995 to 2007. We find evidence of an increased risk of business failure for the portfolio companies with a short forecasting horizon (within one year). The absolute increase in the sample is however small.

The progress of chronic disorders such as heart failure and chronic obstructive pulmonary disease affects various aspects of life. They have an deep impact on patients´experience of health and wellbeing and their functional qualities and quality of life. Several studies have in an extensive way described heart failure and chronic obstructive pulmonary disease in its own domain but few qualitative studies consider coexistence of the disorders from a caring science perspective. The aim was to describe the meaning of living with heart failure and chronic obstructive pulmonary disease from a lifeworld perspective. With a phenomenological and reflecting lifeworld approach it´s possible to describe eight patients daily experiences of living with severe and chronic disorders from their own narratives.

Renal dysplasia in dogs is a severe kidney disease that causes great suffering for the affected individual. The disease disturbs the development of the kidneys which leads to an immature microscopic structure of the kidney and smaller kidneys than normal. A dog with renal dysplasia only lives between 4 and 24 months, because of kidney failure. There are different ways to establish a diagnosis, but the most common way today is to take a renal biopsy. In a scientific study, ultrasound based diagnosis was shown to match the histopathological picture of the disease.

This student report is a literature study about cardiac insufficiency in cats and it is written mainly for veterinary nurses. It is about cats with an underlying heart disease that has led to an incompensated heart failure.It presents a general basis on normal anatomy and physiology, and also how to make the diagnosis, therapy and intensive care.The student report is also about the role of the veterinary nurse during the process of the disease, how to help the veterinarian in the best way, how to handle anesthesia in cats with a heart disease, which factors that can have a significant matter in feeding, and what advices to give to a pet owner with a cat with a incompensated heart failure..