This literature study aims to examine the existence of cancer stem cells in breast cancer. The cancer stem cell theory states that there is a hierarchical organization within a tumour, in which a small subpopulation of the cells can initiate new tumours and maintain tumour growth whilst the bulk of the tumour cannot. These tumour initiating cells have shown to possess many characteristics similar to those of adult stem cells, which is why they are often referred to as cancer stem cells. Both cell types have the capacity of asymmetric division and have shown to possess mechanisms of resistance to both apoptosis and cancer drugs. The cancer stem cell theory elucidates many biological aspects such as the heterogeneity of tumours and the relapse of many cancers after what appeared to be successful treatments.

When different type of programs are developed one wants to make these adjustable to future changes and requirements. It must be done a good design of the program from the beginning to make it possible to continue development of it without having to redo big parts of it to high costs. In the area of object orientation there are design pattern, which can be used to design systems that can be adjusted to new changes in an easier way. I have in this thesis chosen to take a closer look at how to design a program that sends SMS to cell phones through a system of an operator. One requirement on the program is that it has to be possible to change what operator to send though in an easy way.

Denna rapport behandlar utvecklingen av den spelmotor samt spellogik som används i speletSteam Tale utvecklat under projektnamnet Project Steam Age av gruppen StormBound. Speletutvecklades i första hand för mobila enheter, och i rapporten ingår även en kort undersökningav mobila spel i ett historiskt perspektiv. Även spelets genre, JRPG, en förkortning avJapanese Role Playing Game, kommer att förklaras som hastigast med referenser till andraspel inom genren.Spelet programmerades för Android OS version 2.3 och framåt i språket Java. En avsvårigheterna som påträffades, såsom beskrivs i rapporten, var att säkerställa att speletfungerar för den varierande prestanda som mobila enheter utgör, inklusive aspekter såsommed eller utan hårdvaruacceleration av grafik, varierande mängd lagringsutrymme ochprocessorkärnor samt storlek på skärmar. Därtill bör man vid skapandet av en applikation avdenna typ beakta resurshantering, framförallt beträffande grafik och ljud, ett ämne sombehandlas i denna rapport..

Xylem är ett världsledande företag inom vattenteknologi. Xylem hade år 2011 mer än 12000 medarbetare i över 150 länder. Xylem Water Solut-ions är den största enheten och har huvudkontoret i Stock-holm/Sundbyberg där vi har fått möjligheten att göra vårt examensar-bete.För att läsa och presentera prestanda på pumpar och motorer används ett program som heter PECU som körs i UNIX. För att använda PECU på PC används en klient som heter Jmenu. Jmenu utvecklades för många år sedan och är idag krångligt att installera, uppdatera och distribuera.

I det här examensarbetet undersöker vi kommunikationsförhållandet mellan ett utvalt mikroföretag och den kommunala miljömyndigheten med avseende på miljöbalkens bestämmelser. För att tillgodogöra oss empirisk kunskap över detta problemområde har vi inom ramen för en fallstudie genomfört kvalitativa intervjuer med nyckelpersoner hos områdets signifikativa aktörer. Syftet med en sådan undersökning följer av att försöka problematisera förhållandet mellan miljömyndighetens kommunikation av miljölagstiftning och företagets drivkrafter för att bedriva ett systematiskt miljöarbete. Resultaten av undersökningen visar att det studerade företaget upplever vissa svårigheter med att förverkliga miljökrav som den kommunala miljömyndigheten kommunicerar. Härmed kvarlämnas således företaget i ett vidare behov av stöd och rådgivning för att effektivt kunna uppfylla ställda miljökrav.

Syftet med denna uppsats är att undersöka om revisionsplikten för små och mikro AB bör finnas kvar eller inte. Inom den Europeiska Unionen (EU) är det endast Sverige och Malta som i nuläget har plikten kvar fullt ut. För att få en uppfattning om vad debatten handlar om har vi i första hand studerat aktuella artiklar. Vi har även använt oss av två olika forskarrapporter inom området och litteratur. Åsikter i debatten har vi även tagit del av genom sju stycken olika intervjuer med anställda hos banker, Skatteverket, revisionsbyråer och ägare i små och mikro AB.

This study examines how Sweden?s four biggest newspapers deal with the attacks in Oslo and on Utøya the 22nd of July 2011. This date, where the ethnic Norwegian Anders Behring Breivik, bombed the goverment headquarter and killed 69 people at a political camp, will be remembered for a long period of time.  With its critical perspective, this study examines a total of thirteen news articles published within eight days after the attacks in Oslo and on Utøya, to see in what way the Swedish news papers constructs Breivik as a person. Furthermore the study examines in what way the Swedish newspapers makes connections to Sweden and to what extent speculation is used in the news articles. The theoretical premises for the study are the critical discourse analysis, and key elements within it that is used are ideology, discourse and micro- and macro analysis. The conclusion shows that Swedish newspapers are disposed to construct Breivik as a unique individual who falls outside the normative scopes in their explanations of a murderer or a terrorist.

AbstractIntroduction: It has during the latest years occurred several large business scandals both abroad and in Sweden where auditors have been involved. The need for stabile conditions and well functioning professional codes of ethics for companies, especially auditing firms have been growing during the latest years. FAR has seen it as their task to define the meaning of the Swedish term ?god revisorssed?. This is specified through FAR?s nine professional codes of ethics, which came out in a new edition in 2003.

This bachelor?s degree project in social anthropology examines how teachers and school staffin grades 7-9 navigate between relationship-building work and the maintenance of authority.By studying interactions in both classrooms and informal environments, such as corridors andcommon areas, the study highlights how these dimensions take shape in concrete everydaysituations. The aim is to deepen the understanding of how teachers in practice balance thedemands for closeness and trust against the need for order and boundary-setting. The mainargument of the thesis is that relationship-building and authority do not constitute opposingpoles, but are closely intertwined practices that are constantly shaped and negotiated througheveryday micro-actions. This balancing act, described through the concept of ?hugs withboundaries?, is deeply situational and requires staff to continuously adapt their approachaccording to the specific situation and student group.

The main objective of this study is to divide a number of colorectal cancer cases into subgroups based on their molecular features using cluster analysis. The data used is supplied by a research group at Pathology, the Department of Medical Biosciences, Umeå University, and consists, after some preparation, of 455 observations which is a larger data set than many similar studies. The molecular variables that the clustering is based on are CIMP (CpG Island Methylator Phenotype), MSI (Micro Satellite Instability), BRAF- and KRAS-mutations. These are categorical variables and consequently the clustering method used is PAM (Partitioning Around Medoids) which is particularly useful with data on diverse variable level. The final analysis results in four subgroups that are represented by different combinations of attributes on the aforementioned variables.

This bachelor?s degree project in social anthropology examines how teachers and school staffin grades 7-9 navigate between relationship-building work and the maintenance of authority.By studying interactions in both classrooms and informal environments, such as corridors andcommon areas, the study highlights how these dimensions take shape in concrete everydaysituations. The aim is to deepen the understanding of how teachers in practice balance thedemands for closeness and trust against the need for order and boundary-setting. The mainargument of the thesis is that relationship-building and authority do not constitute opposingpoles, but are closely intertwined practices that are constantly shaped and negotiated througheveryday micro-actions. This balancing act, described through the concept of ?hugs withboundaries?, is deeply situational and requires staff to continuously adapt their approachaccording to the specific situation and student group.

The calcium homeostasis in the body is normally strict regulated to be kept within very narrow limits. This regulation is due to the action of parathyroid hormone (PTH) which is synthesized in the chief cells of the parathyroid glands. In different diseases, the calcium homeostasis is disturbed and this could either be due to a dysfunction of the parathyroid gland itself, or it could have a completely different explanation. To investigate disturbed calciumhomeostasis, ionized calcium and PTH can be analyzed from a blood sample. There are a lot of different assays to measure PTH in humans.

Cycling is one of the most sustainable transport modes available and it is widely promoted inmany urban areas. The health benefits from cycling has shown to be substantial, includingdecreased risks of diseases related to overweight and enhancing brain capacity. However, inurban areas cyclists can temporaly be exposed to high levels of air pollution, resulting inhealth risks as opposed to health benefits.The objective of this thesis is to develop a rasterbased test model in GIS that estimates theinhaled dose of air pollution for cyclists based on relative particle concentration in differenttransportation micro-environments. The method used is a least-cost path approach,calculating three different routes; shortest, fastest and least dose for four different trips withinSödermalm, Stockholm.The results show that the inhaled particle dose can be greatly reduced, 39% - 58% for three ofthe routes, by choosing the least dose route. One of the most interesting findings is thesubstantial increase of dose when high levels of particles are combined with uphill cycling.The conclusion for the thesis is that a raster-GIS model can be very useful for estimating doseof different air pollution particles and chemicals along cycling routes.

In Sweden there is an integration policy and a policy for national minorities. The integration policy aims to integrate newly arrived immigrants (nyanlända invandrare), whereas the minority policy aims to maintain and strengthen the rights of the national minorities. The national minorities are though, at times, included into the integration policy, even though they hold a minority status in Sweden. This paper aims to, through discourse analysis, investigate the research question: ?how is the content of integration referred to, when it is related to immigrants, contra when it is related to national minorities?.

Distillers? grain is a by-product of ethanol production. Corn, wheat and barley are the grains that are generally used in the distillery process. Distillers? grain is rich in protein and phosphorus.