The aim of this master thesis was to examine a possible connection between chromatin functions and the DNA damage repair system, with the imprinted IGF2/H19 locus as a bait. Interactions can occur within and between chromosomes and it has been shown that H19 ICR on both alleles can communicate with alleles on other chromosomes. The methylation-sensitive insulator protein CTCF is bound on the maternal H19 ICR and acts as an insulator by blocking the IGF2 promoter to access its enhancers. This is possible by formation of loop structures by CTCF that enables intra and inter-chromosomal interactions. CTCF is poly(ADP-ribosyl)ated by PARP-1 when it is bound to H19 ICR.

Examensarbetet formulerar förutsättningar för ett samtida stationssamhälle utifrån utvecklingen av stationssamhällen utefter järnvägsdragningarna på 1800-talet och dagens förutsättningar. Arbetet är indelat i fem delar. Den första beskriver uppkomsten och utvecklingen av stationssamhällen fram till idag. I del 2 beskrivs det samtida stationssamhället utifrån historien och dagens förutsättningar. Beskrivningen utgår ifrån de tre ledorden som är viktiga i utformningen av samhället; rörelse, mötesplats, blandning.

Syfte med denna undersökning har varit att belysa tidigarelärares uppfattningar av demokrati­upp­draget i 2000-talets skola. Vi har noggrant valt ut forskningsfrågor för att uppnå syftet. Vi har genomfört kvalitativa intervjuer med fem lärare riktade mot tidigare år. Frågorna grundar sig i det syfte vi vill belysa. Resultatet består av delar av intervjuerna som vi valde att lyfta fram utifrån våra forskningsfrågor.

The purpose of this paper is to examine how six students who attend a high school relate to their multilingualism and emphasize how their multilingualism has affected their views of themselves and their identity. The fundamental questions were:How do six students who attend a secondary school relate to their multilingualism?How has students' multilingualism affected their views of themselves and their identity?I did use a qualitative research method in terms of interviews to receive answers for my inquiries.Carla Jonsson (2010) speaks inter alia about ?the third space? which concerns adolescents creating a ?third room?. Almqvist (2006) believes that adolescents that are exposed to discrimination and prejudices can lead to them turning their backs on society in disappointment. Boyd (1985) has, in his thesis, found that multilingual students communicate with the majority language and with their mother tongue with their parents.

AbstractEffective January 1, 2005 publicly listed companies were obliged to adopt a new financialreporting standard (IFRS/IAS). The objective of IFRS/IAS was to increase transparency andcomparability in financial reports between companies. The authors have chosen to write aboutIAS 40 where the accounting treatment for investment property and related disclosurerequirements are regulated.The purpose of this thesis is to investigate potential effects of valuation of investmentproperty at fair market value for real estate companies at times when market price decreasesand to investigate what an acceptable difference for the valuation could be.To fulfil this purpose the authors have chosen a qualitative method interviewing accountants,property analysts and a credit analyst to obtain a deeper understanding of the problem. Basedata for the thesis have been collected during meetings, telephone interviews and e-mails.Additional data was collected from public available sources such as the internet, relevantprofessional magazines and professional newsletters. The authors have designed a modelshowing how Income and Balance Sheet statements are influenced by changed valuation ofinvestment property.

Since the beginning of the new millennium, China has opened itself to the outside world and in an enormous pace increased its contacts and relationships with other countries. The trigger to these dramatic changes of economic and foreign policies is the insight that China can no longer sustain its rapid economic growth, largely based on industrial production, on energy and raw materials from China alone.Good relations with African countries have been of highest priority in China?s strategy of ?Going global?. The new African policy is based on the two principles of mutual benefit and non-interference in internal affairs ? as opposite to the West?s strategy of structural adjustment programmes (SAP), which include massive interference in internal affairs.

Bakgrund Arbetsterapeuter har kompetens inom aktivitet och g?rande och kan utforma inter ventioner f?r alla ?ldrar. Musikterapi ?r en intervention som anv?nds f?r att fr?mja h?lsa genom upplevelsen av musik. Varje ?r ?r det 25 000 personer som insjuknar i en demenssjukdom och n?r en person f?r en demenssjukdom kan den social interakt ionen vara n?got som gradvis kan minska, vilket kan leda till ensamhet.

Central African Republic has partly been portrayed in the media as a forgotten crisis, but also as something that is completely natural for how it is in Africa. The society has perceptions about Africa, which has been reproduced and reconstructed in the selected articles. The discourses in particular have appeared in articles are discourses about: us and them, the confidence in experts, social representations especially (emotional roots), ideological inequities and power relations between different parties..

Syftet med denna studie har varit att undersöka hur ämnet motorik i trä-ningsskolan genomförs, hur pedagogerna går till väga vid planering och upplägg och ?tänket? bakom. Författaren ville med detta arbete fördjupa sin förståelse och kunskap om hur man uppnår en individuellt anpassad motorik för eleven samt visa på likheter, skillnader och gemensamma nämnare i tankegångar, planering och arbetssätt. En kvalitativ metod har använts och i studien har tre pedagoger som är ansvariga för ämnet motorik på träningsskolorna intervjuats. Informanternas utsa-gor samt relevant litteratur ligger till grund för detta arbete.

The aim of this study was to explore whether the patients? expectations of physiotherapy correspond with the physiotherapists? view of their own professional role. Two separate questionnaires were used, one to the patients and one to the physiotherapists, which questions were able to compare. Totally 41 patients and 6 physiotherapists answered the questionnaires. The low number of answers from the physiotherapists made it impossible to fulfil the purpose.

This thesis is an attempt to study how a library that is driven by a contractor works. How allinvolved parts can cooperate. The main method used, is qualitative interviews. The authorshave made a survey at the public library in Järna in Södertälje county, where Boktjänst i JärnaAB has the business on contract since 1991.Following areas have been studied: organisation and assignment; librarysphere of activity andservices; the relations to the main library, and the vision for the future of the library.Some of the conclusions drawn by the authors are that when tenders are invited for a job, thelocal conditions must be taken into consideration. To have the same employer for the wholelibrary staff are likely to simplify the matters.

Syftet med undersökningen är att se om och hur pedagoger konstruerar genus och traditionella könsroller i skolan. Vi har valt att använda oss av den kvalitativa och halvstukturerade inter-vjun som metod. Vi har intervjuat fyra pedagoger i grundskolans tidigare år för att undersöka hur de talar om traditionella könsroller och genus. Vi vill se om pedagogerna förstärker eller förebygger traditionella könsroller och genus i skolan.I läroplanen för det obligatoriska skolväsendet (Lpo 94) står det att personal inom skolan ska arbeta för att främja jämställdheten samt bryta de traditionella könsroller som finns. Vi menar att det är pedagogers skyldighet att arbeta för en jämställd skola.

Orofaciala funktioner såsom mimik, tal, tuggning och sväljning är viktiga för livskvaliteten. Det råder generell brist på normerade test som bedömer dessa funktioner och därför har Nordiskt Orofacialt Test ? Screening (NOT-S) utvecklats. Syftet med föreliggande studie var att normera NOT-S för barn med typisk utveckling i åldrarna 3:0-6:0 år. Testet består av en strukturerad intervjudel och en undersökningsdel med sex avsnitt vardera.

The purpose of our study was to establish whether the knowledge about vegetarian diet was enough among nurses in order to practise professional nursing. We made an empirical study based on a questionnaire. Twenty-one registered nurses answered the questionnaire that consisted of mostly open questions. The result showed that almost everyone experienced that they gave dietcounselling and many nurses mentioned that dietcounselling was important. The majority of the nurses thought that they had enough knowledge to be able in order to deliver a fundamental dietcounselling but nobody considered that they knew much about vegetarian diet..

The aim of this master thesis is to create an understanding of what it can be like to grow older as a homosexual man in Sweden today. The study has an intersectional and queer theoretical approach and is based on eight in depth interviews with men who are aged between 68 and 82 years old. In the analysis I deal with the problem of how sexuality can be inter- preted with the experience of aging. Central to the analysis is the criticism of norms connected to age, sexuality, social- and family life and gay culture.The results show that the norm-breaking sexual orientation of the men affects their life path in terms of how to organize social life, where friends often replace the traditional family. New ways of forming relationships and living their lives imply other obligations rather than the traditional for significant others, which was shown to influence the expectations and outcome of old age in terms of care and support.