Background: Sleep-disturbances in persons with Alzheimer´s disease are prevalent. They are characterized as increased frequency and duration of awakenings, decreased slow-wave sleep, REM-sleep and increase of day-time napping. Depression and lower quality of life are associated with sleep-disturbances. Altogether a significant source of stress for caregivers and an important factor in institutionalization. Non-pharmacological treatment alternatives are rare.Method: Single-case A-B-C design, with non-concurrent multiple baselines, a pilotstudy.Aim: To explore if an educational program on sleep, sleep disturbances and behavioural change directed towards caregivers improved sleep, depression and quality of life in persons with Alzheimer´s disease living at home.

Amyotrophic lateral sclerosis is a progressive neurological disease which causes a slow degeneration of the body. Living with this disease means being exposed to severe strain and every day could bring new losses. Amyotrophic lateral sclerosis does not cause any harm to the intellect, the mind remains unaffected. The aim of this study was to achieve an understanding, and to shed light on the nature of positive life experiences of people living with amyotrophic lateral sclerosis. This literature study is based on detailed examination of three person's narrations taken from their autobiography and biographies.

Abstract Background: Type 1 diabetes is a chronic disease that worldwide greatly increases among children and adolescents. Major demands are required from the individual who has this disease, which also requires significant knowledge from the nurses so they can be able to develop and create individual conditions for children and adolescents. Thus, the children and the adolescents can be able to take responsibility and feel secure in their own care. The nurse's techniques and specific tools in this work are however not particularly noteworthy and therefore needs to be advised.Aim: The aim of this study was to describe the experiences nurses have of supporting adolescents, between 12-18 years, with type 1 diabetes to an increased understanding of the disease and also to examine the methodological aspect data collection in the articles of this study. Method: A descriptive, literature study according to Polit and Beck (2012).

The purpose of this degree project is to clarify how five Kenyan Life Skills teachers discuss about hiv and aids education. Furthermore, to reveal whether the validity claims in their verbal communication refers to facts, morality or personal experiences. This, I will study by examine the teachers knowledge of, and attitudes towards, the disease. The teaching methods they are using and the basis of their validity claims. I have chosen to use semi-structured interviews as method and the theoretical framework is based on Jürgen Habermas theory of universal pragmatics.My result shows that there is a dilemma about whether the respondents knowledge is sufficient or insufficient.

Proliferative enteropathy is a group of disease conditions in pigs where the disease may vary from subclinical to critical with bloody loose feces. The etiological agent is the obligate intracellular bacteria Lawsonia intracellularis. L. intracellularis infects enterocytes from jejunum to colon. The bacteria is taken into cells and start to replicate and cause a massive proliferation of immature enterocytes.

Breast cancer is the most common tumor disease among women in Sweden. About 7000persons, having a median age of 65, are diagnosed each year with this disease. Withmammography screening, breast cancer can be detected in an early stage which improves theoverall survival (OS). 20-30 % of the breast cancer tumors are overexpressing humanepidermal growth factor receptor 2 (HER2), which is a protein that stimulates cell proliferation.Trastuzumab (Herceptin®) is a humanised monoclonal antibody that targets the HER2-proteinand prevent the signals for cell proliferation.Trastuzumab has earlier been used for treatment of metastatic breast cancer. In the year of 2007trastuzumab was approved for adjuvant treatment of patients who has been medicated withsurgery and/or radiation.The aim of this study was to investigate the effects of adjuvant treatment with trastuzumab inHER2-positive breast cancer patients.

Most of the people in today's society have at least some knowledge about Alzheimer's disease to some extent. When a person with Alzheimer's disease is being taken care of at home, the relatives have to change their own priorities and readapt themselves to the existing situation. The primary aim of this study is to describe how the relatives experience their own situation in life. The secondary aim of this study is to describe how the relatives understand their own relation with the health care authorities concerning the help and support issues. The authors have realized this study using the analytic inductive method and have interviewed four informants using a semi structured interview guide.

Denna uppsats tittar närmare på fyra verk av Jenny Holzer. Hennes konstnärskap jämförs även med Guerilla Girls. Huvudmetoden utgörs av bildanalyser och jag presenterar också tolkningsmöjligheter utifrån ett genusperspektiv. Utöver detta har jag med en konsthistoriografisk undersökning fått fram hur den generella bilden av Holzer ser ut..

Hydropericardium or pericardial effusion (PE) is the accumulation of fluid in the pericardial sac and is often secondary to pericardial diseases or diseases related to the heart. It is unusual with clinically relevant pericardial diseases in cats but pericardial effusion is the most common one. Since PE causes serious symptoms and may lead to death it is important with a quick diagnosis and treatment. PE can be acute and cause cardiac tamponade, which gives severe clinical signs. Cardiac tamponade needs to be treated immediately or else the cat will die from cardiogenic chock. More common is chronic PE where the fluid accumulates during a longer period of time and the pericardial sac stretches.

Breast cancer is the most common tumor disease among women in Sweden. About 7000persons, having a median age of 65, are diagnosed each year with this disease. Withmammography screening, breast cancer can be detected in an early stage which improves theoverall survival (OS). 20-30 % of the breast cancer tumors are overexpressing humanepidermal growth factor receptor 2 (HER2), which is a protein that stimulates cell proliferation.Trastuzumab (Herceptin®) is a humanised monoclonal antibody that targets the HER2-proteinand prevent the signals for cell proliferation.Trastuzumab has earlier been used for treatment of metastatic breast cancer. In the year of 2007trastuzumab was approved for adjuvant treatment of patients who has been medicated withsurgery and/or radiation.The aim of this study was to investigate the effects of adjuvant treatment with trastuzumab inHER2-positive breast cancer patients.

The aim of this study was to identify possible reasons for non-attendance related to mammographic screening. Using qualitative methods, sex women underwent a semi-structured interview on the following themes: social background, medical history, mammographic screening, invitation, and final decision.Social background was described using the "life-form theory". The concepts of illness, disease, and sickness were used in order to investigate medical conditions and their impact. The process of non-attendance was studied using a model by Zovko, balancing different needs affecting decisions and final action.According to their decision, and final action, women were defined as "participants", "passive non-attenders" or "active non-attenders". Most women belonged to the life-form "paid work" and had children.

This literature study describes the ways in which the spread of rabies can be prevented in India, what guidelines are set and also which methods have proved most effective. Every year rabies causes the death of around 20 000 people in India, which makes the prevalence in the country the highest in the world. The main source for human infection is bite wounds from infected dogs. People and animals can be vaccinated both prophylactic and post-exposure prophylactic (PEP), despite this the disease continues to claim high number of victims. The majority of those dying are young men and children from the poorer part of the population. Knowledge among the Indian population on rabies and its transmission routes, wound care and vaccinations is very limited.

Hypertrophic cardiomyopathy (HCM) is the most common heart disease in cats. Maine coon is one of the breeds where the disease is overrepresented. Studies have shown that HCM is inherited as an autosomal dominant trait in Maine Coon cats. This finding has led to cardiac screening using ultrasound in the breed. The results of the screening are used in a national breeding program constructed to reduce the spread and incidence of HCM in Maine Coon cats.

Introduction The genetic skin disease epidermolytic ichtyosis is caused by mutations in either keratin gene 1 or 10 and leads to blisters and hyperkeratosis of the epidermis. At cellular level the disease is seen as aggregates in the keratin filaments. Since medicines are hard to investigate and produce mainly due to lack of reproducible model systems, there is no good treatment available for this disease today. In this article we describe how an in vitro model consisting of cells from a stable cell line transfected with expression plasmids to mimic patient cells, may be a possible alternative for screening compounds for therapies. The first step was to generate an expression plasmid required to complete the in vitro model.

Hydropericardium or pericardial effusion (PE) is the accumulation of fluid in the pericardial sac and is often secondary to pericardial diseases or diseases related to the heart. It is unusual with clinically relevant pericardial diseases in cats but pericardial effusion is the most common one. Since PE causes serious symptoms and may lead to death it is important with a quick diagnosis and treatment. PE can be acute and cause cardiac tamponade, which gives severe clinical signs. Cardiac tamponade needs to be treated immediately or else the cat will die from cardiogenic chock. More common is chronic PE where the fluid accumulates during a longer period of time and the pericardial sac stretches.