The Bovine respiratory syncytial virus (BRSV) causes bronchiolitis and interstitial pneumonia, predominantly in calves, and is a major cause of bovine respiratory disease worldwide. In humans, BRSV is paralleled by the closely related Human respiratory syncytial virus (HRSV), an important cause of respiratory disease, most severe in infants.The clinical signs and pathology during RSV infection is caused, not only by the direct effects of viral replication, but also by the response of the host immune system. The immunopathology of RSV has long obfuscated our understanding of the disease, and development of effective treatment and vaccines will be very difficult until greater knowledge is gained.One of the components of the immune system that has come into focus in RSV research the last few years, is the Toll-like receptor 4 (TLR4). The TLR4 receptor is well known as the receptor that binds lipopolysaccaride (LPS), and initiates the host response to bacterial infection. Recently, it has been shown that the fusion protein of RSV also interacts with, and up-regulates the expression of, the TLR4 receptor.

In studies of serum, in the early 1930s, from patients with pneumonia, a factor was found. It could agglutinate certain pneumococcal species. This factor, which later became known as C-reactive protein (CRP), increased sharply during the early and middle stages of the disease. CRP was identified as an acute phase protein and found especially in bacterial infections. CRP is synthesized in the liver by stimulation of interleukin 6 (IL-6), which is produced by the monocytes, and consists of five non-covalently bound subunits.The aim of this study was to compare two different analytical instruments (Vitros 5.1 FS Ortho-Clinical Diagnostics and QuikRead CRP Orion Diagnostica) for CRP analysis.

Background: Type 2 diabetes is a disease which causes vascular damage, stroke and premature death.Oxidative stress may play a role in the development of insulin resistance and diabetes. Selenium is amineral involved in the protection against oxidative stress, and has been thought to be favorable in theprevention of the disease. However, this has changed since trials observed positive correlationsbetween high selenium levels and incidence of type 2 diabetes.Objective: To examine the studies that investigates seleniums effect on the incidence of typ 2 diabetesSearch strategy: Searches have been done in PubMed and Scopus.Selection criteria: Included studies were human studies in English/Swedish with RCT or cohortdesign with the aim to investigate the correlation between selenium and incidence of type 2 diabetes.Excluded studies were studies whose aim was to investigate the role of selenium in patients withexisting diabetes. Studies regarding pregnant women, animals or children and with in vitro design werealso excluded. Of the studies found in Scopus where MeSH terms were available, the ones who did notinclude relevant terms were excluded.Data collection and analysis: Studies were collected according to the aforementioned criteria.

 Sammanfattning Datum: 2009-05-29 Nivå: Magisteruppsats i ekonomistyrning, 15 högskolepoängFörfattare:Magdalena Stål, Födelseår: 1982, Bostadsort: Västerås                                Marina Vokbus, Födelseår: 1982, Bostadsort: VästeråsHandledare: Leif CarlssonTitel: Uppförandekoder - En studie i hur tre företag arbetar med etiska rikt­linjerSyfte:  Syftet med uppsatsen är att studera varför de undersökta företagen enligt respondenterna upprättar en uppförande­kod och vilka etiska principer koden baseras på. Vidare är syftet att studera vilka områden uppförande-koden omfattar, vad företagen fokuserar mest på samt vad de gör för att efter­leva sin uppsatta uppförandekod.Metod: Undersökningen bygger på en kvalitativ forskningsmetod där primär­data studerades i form av insamlat intervjumaterial. Tre företag inter­vjuades angående deras arbete kring etiska riktlinjer. De företag som undersöktes var Atlas Copco, The Body Shop och Samhall.Slutsatser: Anledningen till att de undersökta företagen upprättar en uppförande­kod skiljer sig åt. Atlas Copco ser det som en möjlighet till affärer och långsiktig lönsamhet, för The Body Shop ingår det i den ursprung­liga affärsidén att utföra goda gärningar och Samhall har som ett statligt ägt företag krav på sig att leva upp till uppsatta mål.

I denna magisteruppsats har kassagränssnittet som används på kosmetikkedjan The Body shop utvärderats med avseende på hur det stödjer säljarna i sitt arbete. Syftet har varit att se vad säljares kognitiva belastning är under deras arbete och att ta fram ett kassagränssnitt som minskar denna. Studien har genomgått tre faser där den första, ?Undersökningen?, syftade till att undersöka vilken typ av kognitiv belastning säljarna utsätts för. Detta studerades genom att säljare intervjuades och observerades under användning av det befintliga kassasystemet.

ABSTRACT Epilepsy describes a neurologically caused condition which involves seizures. Epilepsy can be classified according to different types of causes and the nature of seizures can vary. Medication for epilepsy in dogs is limited in comparison with human medicine. Idiopathic epilepsy is the most common neurological disease and one of the most common genetic diseases in dogs. Because epilepsy has a higher prevalence in certain breeds, there is reason to suspect that it is a hereditary disease. The inheritance of idiopathic epilepsy is for most breeds not determined, except for a few variants of the disease.

Chronic valvular disease (CVD) is the most common cardiac disease in dogs, which account for 75% of all the cardiac cases. Cavalier King Charles spaniel (CKCS) is the most affected breed and it´s 13th times more likely that a CKCS, between the age of 7-10 years, will die or be euthanized for cardiac disease, compared with other breeds. The prevalence has been proven to bee independent of coat color and weight but highly dependent on age and gender in CKCS. In 2001 the Swedish Kennelclub and the Special club for cavalier King Charles spaniel created a breeding program against CVD in CKCS. In this program dogs are not allowed to breed until 4 years of age and have to have a heart auscultation without murmurs.

Introduction Malignant lymphoma is the most common haematological blood cancer diagnosis. In spring 2013 a questionnaire was handed out to patients with various haematological malignancies. The results showed that the patients requested more verbal and written information about their disease and treatment. Providing information about chemotherapy and how it affects the patient's quality of life is part of the nursing care. Communication between nurse and patient is very important to share experiences and knowledge with each other Aim The aim is to describe the information and communication patients with malignant lymphoma demand, based on their own experience, in meeting with the nurse before and during curative chemotherapy treatment at a haematology outpatient clinic.

Haptoglobin is an acute phase protein with important biological role because of its capacity to bind to haemoglobin. Haptoglobin exists in three major genetic polymorphism types: Hp1-1, Hp2-1 and Hp2-2, the distribution of which has been associated with abdominal aortic aneurysm (AAA), an asymptomatic aortic disease common among men older than 65 years.    Five different electrophoretic methods were tested according to their ability to separate the haptoglobin phenotypes. The detection was based on a produced hemolysate of blood in which haemoglobin binds to haptoglobin thereby forming a complex that can be detected by specific haemoglobin staining using TMB-dihydrochloride and hydro peroxide as substrate resulting in an azure-green color of the bands. Samples from 15 patients who had suffered surgery for not broken AAA, that is more than5.0 cmaortic diameter, and 15 samples from matched controls were analyzed.    Among the five tested electrophoretic methods best migration and separation was seen on the pre-cast agarosgel Hydragel HR on the instrument Hydrasys. The other four methods gave less successful results.

The United Nations is an important organization when it comes to international peace and security. Recent events in international politics, however, have brought about a widespread concern about the abilities of the organization. Powerful states have shosen to act outside of the organization to achieve their goals. They have furthermore a disproportionate influence on the decision-making body, the Security Council.The aim of this essay is to examine wheather UN can function productively as keeper of the international peace and security in the political climate of today, and to find out to what extent the powerful states harm the organization. I use a theoretical article, concerning states relations to international organisations, to analyse the acts of powerful states in UN.

The last decades the increased computerisation at the places of work has led to new physical loads in the working life and new demands on the working environment. The widespread usage of computers in the working life has led to more sedentary work and less daily movement.The purpose of the thesis is to develop a new product to a concept that in a low intensive and healthy promotional way will activate the body. The product will make a combination of healthy promotion activity and work during office hours possible and primary aims to those with a sedentary office work, which leads to that the body don´t get to be activated in the extent needed.Information has been gathered from studies already made in this area, interviews plus a study and an experiment. From the gathered information concepts and functional solutions has been generated and evaluated to result in a product concept.The thesis has resulted in a concept that consists of a work place unit where the user walks on a treadmill and works at the same time.A general conclusion which can be drawn is that the majority of persons that tested to walk and simultaneously work with a computor on the treadmill found this way of working attractive. Many were positively surprised and said that they would use such an physically activating work place implement if it was available at their place of work..

During the last decade of the twentieth century both ?manhood? and gender studies seems to have undergone changes. With the field of masculinity and the critical studies of men, added as ?subsections? of broader gender studies, new knowledge has been produced to better grasp the production of gender and power relations of patriarchy. During the same decade as the ?metrosexual? first appeared of the urban stage, acts of homophobia and attitudes towards ?manhood? seems to have changed.

Inledning: Prevalensen av karies och övervikt/fetma hos barn och ungdomar beskrivs kort. Syfte: Att kartlägga och analysera studier som undersökt sambandet mellan kariesprevalens och BMI hos barn och ungdomar. Följande frågeställningar ska besvaras: Finns det en korrelation mellan kariesprevalens och BMI? Har gruppen överviktiga barn och ungdomar högre kariesprevalens? Har gruppen underviktiga barn och ungdomar högre kariesprevalens? Metod: Frågeställningarna besvaras med hjälp av en systematisk litteraturöversikt. Resultat: Utav sammanställningens 28 artiklar visade 14 på samband mellan karies och BMI och lika många visade inget samband.

Många företag integrerar idag en social och miljömässig aspekt i sin verksamhet, utöver vad som krävs enligt lag. Det har blivit viktigare för företag att visa sitt engagemang för att gynna hållbar utveckling samt att se till att människor behandlas på ett sätt som anses etiskt rätt. Detta i och med att företagens intressenter, till exempel kunder och aktieägare, blivit allt mer medvetna och ställer större krav. Att arbeta med ett sådant ansvarstagande kallas för att arbeta med Corporate Social Responsibility, vilket förkortas CSR. CSR-arbete förekommer bland annat inom kosmetikabranschen där det miljömässiga, sociala och etiska ansvaret står i fokus, men även det ekonomiska är viktigt eftersom företaget också har ett ansvar gentemot sina aktieägare.

The competitive nature of the automotive industry has always implied a necessity to improve product development concerning time-to-market, cost and product quality. As capacity of computer-aided engineering (CAE) tools has evolved, so has the strive for simulation-driven design. Virtual durability testing using full vehicle models is one of many challenges posed in front of vehicle manufacturers when computer simulations are given a key role in product development.This thesis has been initiated as a preliminary step towards implementing dynamic virtual durability testing in the development of buses and coaches at Scania. The objective has been to assess the predictability of a full vehicle coach model and to what level of precision structural loads can be predicted. Previously performed proving ground testing of a Scania Touring coach has been the basis for the modelling and simulations in this thesis.A virtual model of the Scania Touring coach has been created in multi-body simulation software package MSC.Adams.