In this project a LC-MS-method for the analysis of gamma-hydroxybutyrate, gamma-butyrolactone, 1,4-butanediol, amphetamine and methadone was developed.Initially, the efficiency of the ionisation of the analytes was evaluated with respect to the ionisation technique (ESI, APCI and APPI) and the composition of the mobile phase. In the next step a number of different columns was tested in order to find the one with the greatest potential for separation of the substances in question. Using the selected column, the separation was optimised by means of experimental design and the software The Unscrambler 7.8. The parameters studied were the flow rate, the column temperature and the mobile phase composition. The response variables were the resolution between the target compounds and the retention time of the last eluting compound.These experiments showed that, in order to obtain the best ionisation, the mobile phase should consist of 5 mM formic acid in water and acetonitrile.

The aim is to develop a new decision-making model for credit-loans. The model will be specific for credit applicants of the OKQ8 bank, becauseit is based on data of earlier applicants of credit from the client (the bank). The final model is, in effect, functional enough to use informationabout a new applicant as input, and predict the outcome to either the good risk group or the bad risk group based on the applicant?s properties.The prediction may then lay the foundation for the decision to grant or deny credit loan.Because of the skewed distribution in the response variable, different sampling techniques are evaluated. These include oversampling with SMOTE, random undersampling and pure oversampling in the form of scalar weighting of the minority class.

The thesis is an examination of the methods that are appropriate and long-term choice to obtain clamping force and secure screw joints in production. The employer, Scania CV AB, transmission manufactures axle gears to all trucks produced in Södertälje. One of the most common assembly elements is screw joints, where the clamping force is essential to achieve a secure joint. Current methods to secure the joint is due much of the friction effect and is an indirect method to measure the clamping force. The clampforce accuracy becomes more widely with torque angle control.

There have previously been very few studies of forests on Seram Island in the Eastern Indonesian archipelago and none before on lowland limestone primary forests. The COLUPSIA project on collaborative land use planning has therefore chosen Seram as one of two project sites. The objective of the COLUPSIA project is to establish collaborative and equitable land use planning. In order to achieve its objective the COLUPSIA project aims to improve understanding of traditional resource management and how it interacts with governmental systems, as well as enhancing knowledge about tropical landscapes and ecosystem services.The aim of this study was to contribute to the COLUPSIA project through describing lowland limestone forest on Seram Island in respect to (1) forest structure, (2) tree species richness and (3) tree species composition. We set up 5 plots, each of 0.2 ha, at one site, Mawalai, and collected data on tree variables (tree diameter ?10 cm) as well as for some other life forms and environmental data.

Food-poisoning is a major health problem and an estimated half a million Swedes are food-poisoned annually, with acute gastroenteritis as a consequence. One of the major causes of contaminated foods is related to food- and waterborne viruses. To be able to trace back the source of contaminant, the method of detecting viruses must be specific and sensitive. No standardized method for detecting foods for sapovirus exists today. The aim of the work described in this bachelor thesis is to implement and opti-mize a real-time RT-PCR method for the detection of all genogroups of human sapovirus in foods.

The pathogenic fungus Rhizoctonia solani causes major economic losses for potato producers in Sweden. The producers, as well as advisors, have reported possible increases in severity of R. solani when free-living plant parasitic nematodes are present and active. There are several examples in the literature of interactions between pathogens where one, or both species, support or increase the damage made by the other organism. These complexes are important to investigate and to be able to forecast, since even low incidences of fungi or nematodes may result in an interaction of significance.

From embankment dams is something that has long been noticed and given rise to different questions. The most serious question is if the sludge is a result of inner erosion through the dam, and thus consists of material transported from the dam. Concerns have also been raised whether the sludge could interfere with the systems drainage capacity and thereby lead to high pore pressure in the dam, or if the measurement of seepage is disturbed, as the measuring is usually made via Thomson weirs, which could risk being blocked. The result of this investigation shows that the sludge is a result of the oxidation of iron by iron bacteria, and to the greater part consists of these oxides as well as the bacteria?s own structures. The iron oxidizing bacteria, FeOB, oxides ferrous iron to ferric as a part of their metabolism, and thereby create large quantities of iron(oxy)hydroxides.

Artificiella solljusbilder kan ge positiva ka?nslor och upplevas som naturligt solljus i interio?ra miljo?er. I en tid da?r ljusniva?er och standardva?rden prioriteras blir det unika och intressanta allt viktigare i ljusdesignen. Utifra?n ma?nniskans tendens att fo?redra det naturliga kan ett artificiellt ljus som imiterar det naturliga ocksa? ge va?lma?ende och harmoni fo?r oss.

Opioider är vitt använt på smådjur som smärtlindring och för att minska behovet av anestesimedel. Opioider har också nyttjats på hästar så långt som 70 år tillbaka i tiden men användandet har varit begränsat och kontroversiellt då hästar lätt exciterar på grund av opioider. Metadon är en ?-receptoragonist och detta är den receptor som främst står för opioidernas analgetiska effekt. Metadon är inte godkänd för användning på djur i Sverige men används ändå ofta off-label på grund av sin goda smärtlindrande förmåga.

Det här arbetet syftar till att återinföra frågorna om samhällelig nytta och estetik i debatten kring, och byggnadsprocesserna för vattenkraftverk. Det argumenterar att vår omgivning spelar roll både för vårt psykiska och fysiska välbefinnande och att genom att öppna upp verksamma industriområden till att bli en integrerad del av samhället kan en spännande ny plattform skapas där det finns plats för lärande och förståelse av industriella funktioner samtidigt som helt andra aktiviteter och funktioner också kan finnas. Från att vara en exkluderande plats med bara en funktion går industriområdet till att vara en välkomnande multifunktionell plats. Transparens och deltagande är ledord. Sedan modernismen har industriella miljöer blivit allt mer åtskilda från de städer och samhällen som de ingår i eller gränsar till. Genom funktionsseparering har nya industriella områden tillåtits bilda introverta enklaver som gör sitt bästa för att hålla människor både fysiskt och visuellt uteslutna.

In metabolism Mg plays an important role because it affects many cellular enzymes in the body. The energy metabolism and protein synthesis are dependent on Mg as an enzyme activator, Mg is also involved in the synthesis of RNA and DNA. Absorption of Mg primarily takes place over the ruminal epithelium in ruminants. The main storage of Mg is in the bones but that can only be reached if the cow is in great need of calcium or phosphorus, it's a hormonal regulated process that induces catabolism of bones. Free and available sources of Mg are found in soft tissues and in the extra cellular fluids that includes cerebrospinal fluids and blood.

Sahlgrenska Academyat University of GothenburgDepartment of Internal Medicine and Clinical NutritionAbstractTitle: The effect of naturally existent beta-glucan in adults with hypercholesterolemia. - a systematic review with focus on the Swedish food market.Author: Ida Edman Hellberg, Frida HanssonSupervisor: Mette AxelsenExaminer: Anna WinkvistProgramme: Dietician study programme, 180/240 ECTSType of paper: Examination paper, 15 hpDate: May 01, 2014Background EFSA states in 2010 that there are good evidence that three grams of beta-glucan/day from oat as a part of a balanced diet, has a positive effect on total cholesterol and LDL.Objective Evaluate if there is evidence for primary treatment of lifestyle related hypercholesterolemia with products naturally containing beta-glucan.Search strategyIn February 2014 the databases PubMed and Scopus were used for article research. The search terms used were; cholesterol level, beta-glucan, hypercholesterolemia, oat and barley.Selection criteria Articles, written in Swedish and English, on RCT-studies conducted on otherwise healthy adults with hypercholesterolemia (serum cholesterol >5,0 mmol/L) were included. The intervention product must naturally contain beta-glucan, and an equally product should be retailed in Swedish grocery stores. The control group needed to be supplied with a placebo product and the participants could not be on any lipid-lowering medication.

Feline asthma is a condition very similar to the respiratory disease affecting humans. It is causing, among other things, a constriction of the bronchial airways, an increase of mucus production and damage to, or erosion of, the epithelial membrane. The symptoms occur intermittently and do, in most cases, evolve during a long period of time. The aim of this essay was to investigate whether there are any nursing routines for feline patients with asthma in animal clinics and animal hospitals in Sweden, and if so, to compare similarities and differences. A literary study of research material also led to a suggestion of how to form a nursing routine for this type of patient.

With the prospect of future construction on the Skutskär Pulp Mill property, Stora Enso Fine Paper has initiated an investigation of soil contaminants and a risk assessment of these contaminants. A soil and groundwater investigation has therefore been conducted on an open area of about 16 000 square meters, situated between the current wood room and digester house. To be able to integrate this study into an investigation for the whole industrial property, the study has been carried out as a phase 2 study according to the Swedish Environmental Protection Agency?s Methods of Inventories of Contaminated sites (MIFO).The site investigation has involved soil and groundwater sampling, together with the analysis of heavy metals and organic contaminants. The degree of hazard posed by the contaminants, the level of contamination, the potential for migration of the contaminants, as well as the degree to which protection of human health and the environment is required in the area, have been weighed together for an overall risk assessment of the area with regard to human health and the environment.The investigated area was built up by filling in the coastal waters.

Betongplattor på mark är en ofta använd grundläggningsmetod. Trots detta är sprickbildning ett vanligt problem där kraven på maximala sprickvidder ofta inte uppfylls. De sprickor som bildas i plattorna uppkommer bl.a. till följd av dess uttorkning, och då olika fuktförhållanden råder på var sida om plattan utvecklas en krympning som varierar med en gradient över tvärsnittet. Vid dimensionering av armeringen för denna inre last och sprickbildningen den orsakar, finns endast otillräckliga analysermetoder att tillgå i normer.