This article presents a survey of male dogs treated with the gonadotropin releasing hormone (GnRH) agonist deslorelin (Suprelorin®, Virbac) at three animal clinics in central Sweden. Filled-in questionnaires from 110 dogs were received. The paper also includes a review of existing litterature concerning reproduction in male dogs, focusing on endocrinology, the effects of gonadectomy and the GnRH agonist deslorelin. Continuous treatment with deslorelin produces infertility in male dogs. The pituitary is initially stimulated by deslorelin leading to a rise in luteinizing hormone (LH) and follicle stimulating hormone (FSH) secretion. As a consequence the testosterone levels also increase temporarily.

Det är sedan länge känt att om höns hålls i naturlig belysning varierar äggläggningen med årstiderna. Lägst antal ägg läggs när dagarna är som kortast och ljusstimuleringen är som lägst. Eftersom hönan reagerar även på artificiellt ljus kan ljusprogram användas för att styra antalet ljusa respektive mörka timmar per dygn för att därigenom undvika årstidsvariation. Syftet med denna litteraturstudie är att ta reda på hur ljuset styr hönans könsmognad och ägg-läggning. Ljus registreras av fotoreceptorceller i retina, hypotalamus och epifysen vilka omvandlar energin i fotonerna till en biologisk signal. Vid ljusstimulering stimuleras gonadotropinfrisät-tande hormon (GnRH) vilket ökar frisläppningen av gonadotropinerna follikelstimulerande hormon (FSH) och luteiniserande hormon (LH).

There's a good adherence to the vaccination of children, about 98% of all two year olds are vaccinated. Despite this, there are cases of whooping cough and measles in Sweden. The purpose of the study was to describe what motivates parents to not vaccinate and reflections and attiudes about vaccinations. The study had a descriptive design with qualitative approach. Eight parents who had chosen not to follow the National Board of Health?s vaccination program or whom had decided to completely abandon, participated in the study.

The Northern Raccoon (Procyon lotor) belongs to the Carnivore-family and is a species endemic to North America. Every year hundreds of orphaned raccoon cubs are admitted into the Wildlife Rehabilitation Center of Minnesota (WRCM), a non-profit organization where all injured or orphaned wild animals are admitted and receive quality health care with the goal of being released out into the wild. The WRCM routinely vaccinate all of the admitted raccoon cubs with a killed feline panleucopenia vaccine, but despite this there are outbreaks of parvovirus infection every year where up to 50% of the admitted cubs have been euthanized or died. The objective of this study was to determine whether vaccinating the admitted raccoon kits has any significant protective effect to developing clinical parvoviral disease. A single-blinded cohort study was designed with two parallel, independent groups. One group was given a dose of killed feline parvovirus vaccine at admission, and the other group was not given any vaccination at all. Assignment to the vaccinated or unvaccinated group was on a per-litter basis and done randomly by drawing lots out of a box.

Rabies kills about 55 000 people every year and more than 90% of infected humans are considered getting the disease from dog-bites. To control the disease and eventually eliminate human rabies, the most efficient and economic method is to keep the dog population vaccinated. The objective of this thesis was to evaluate the situation of canine rabies in two urban areas in Lilongwe, Malawi, where canine rabies is enzootic. In each area 200 household-interviews were conducted in September and October 2013. Focal points were awareness of the disease, human incidence as well as vaccination coverage in the dog population.

Bakgrund: Sedan januari 2010 ingår vaccin mot humant papillomvirus i det svenska barnvaccinationsprogrammet. Beslutet att vaccinera eller inte vaccinera sina barn kan vara svårt för föräldrar. Syfte: Var att beskriva föräldrars kunskap om och attityd till vaccin mot humant papillomvirus och hur det inverkar på deras beslut att vaccinera sina barn. Design: Mixed-methods research integrated design. Metod: Beskrivande litteraturstudie.

Det här arbetet är en litteraturstudie som behandlar alternativa sätt till kirurgisk kastrering av smågrisar. Obedövad kastrering av våra smågrisar är i längden inte en hantering som är acceptabel ur djurvälfärdssynpunkt. Problemet är att hangrisen utvecklar två könshormonsliknande substanser, androstenon och skatol som binds in i fettvävnaden och ger ett lukt och smakfel på köttet som kallas för ornelukt. Det är därför grisen kastreras. Den metod som används idag är en obedövad kastration.Vi har beaktat de alternativa metoderna och kartlagt vilka som kan fungera praktiskt och även studerat dem ur en etisk synvinkel.

Alzheimers sjukdom är en smygande neurodegenerativ demenssjukdom som främst drabbar äldre och som karakteriseras av uppkomsten av amyloidplack och neurofibriller i hjärnan. De vanligaste symptomen är demens, kognitiva problem, inbillningar och aggressivitet. Alzheimer förekommer i två olika former, presenil och senil alzheimer. Den fullständiga mekanismen bakom alzheimer är ännu okänd men två proteiner, beta-amyloid och tau, anses ligga bakom orsaken till alzheimer. Ett tredje inblandat protein som man funnit via genetisk analys är apolipoprotein E.

This article starts with a review of the literature regarding the normal reproductive physiology of the mare, prolonged luteal phase and medical drugs used within reproduction of the horse, with emphasis on Ovuplant®. The purpose of this article was to measure the progesterone level in blood, of mares implanted with deslorelin acetate (Ovuplant®). The study was performed at the Department of Clinical Sciences, SLU, in Uppsala. There were seven mares included in the study. They were divided into two groups, one experimental group (four mares) and one control group (three mares).

Det finns många olika typer av bromerade flamskyddsmedel. De är alla stabila i miljön men graden av toxicitet och bioackumulering varierar. Att bromerade flamskyddsmedel är endokrinstörande är känt men min hypotes är att de även är neurotoxiska och att de kan orsaka neurologiska störningar hos människa. Människor exponeras för bromerade flamskyddsmedel via damm och föda. Barn och foster som är känsligare än vuxna kan även exponeras via modersmjölk respektive placenta. Barn har högre serumkoncentrationer av bromerade flamskyddsmedel än vuxna.

Many farms in the counties in the south of Sweden have difficulties with diseases spread by ticks; mainly babesiosis and tick-borne fever (TBF) but there are indications that borreliosis ought to be included. All of the tick-borne diseases radically decrease farm profit if the herd is affected. The production of the vaccine used against babesiosis since the 1920´s, will be discontinued in the near future and in addition to economical reasons it is therefore important to learn more about the diseases above. During the summer and fall of 2002 and 2003, a farm in the island of Gotland was burdened with unusually many cases of bovine babesiosis. In total 43 animals fell ill and one died.

Vaccination as a part of the preventative public health project has for many years been one of the important tasks of the children's health care. The vaccination program has been adjusted to current research and the health situation in the country. Having their children vaccinated is not something obvious for all parents, though. Especially the vaccination against measles, whooping cough and German measles have been questioned. The purpose of this literature study was to investigate the reasons for the resistance to vaccinate and to illuminate the security creating advice of the nurse at the public health centre.

Bovine Respiratory Syncytial Virus (BRSV) is a common cause of respiratory disease among young cattle. The virus causes severe losses; the herd mortality rate can sometimes be as high as 20 %. In this study the avidity (i.e the antigen binding force) of BRSV specific antibodies was measured to see if there was a difference between antibodies produced during an acute phase of infection and antibodies produced by earlier infected animals. A commercially available ELISA-testkit against BRSV-specific antibodies was used and an incubation step with 6M urea was added. The effect of the urea is that it breaks the weak bonds between antibodies and antigen while the stronger bonds remain intact. Four different groups of animals were included in this study; seven calves that were naturally infected, three acutely infected calves with known time of infection, five cows that were seropositive during several years and four experimentally infected calves that had been a part of a vaccine trial. The results of this study showed that antibodies produced during the acute phase of an infection had a low avidity and that the avidity increased with time after infection.

Virulent strains of Staphylococcus hyicus produce exfoliative toxins and cause a potentially fatal skin disease in piglets known as exudative epidermitis. Vaccines and antimicrobials are used to control the disease. Antimicrobial resistance and the prevalence of several different toxin genes and toxigenic strains make it problematic. The aim of this literature study was to identify potential differences between countries and between healthy and diseased pigs regarding antimicrobial resistance and toxin-producing strains. Great differences could influence vaccine production, treatment strategies and surveillance programs.

Introduction: Every year about 450 women in Sweden are diagnosed with cervical cancer, almost 200 die and thousands undergo surgery because of cell changes in the cervix. A HPV infection can lead to cervical cancer and therefor costs for the society. The implementation of a vaccination program against HPV is a way to avoid these costs. Aim: The study aimed to calculate the economic impact of the HPV- vaccination program for children in Sweden through a cost-benefit analysis. Method: In this analysis, status quo was compared with non-administration of the HPV-vaccine for the selected cohort of ten-years-old girls in Sweden.