The Center for Genomics and Bioinformatics (CGB) is an academic department at Karolinska Institute. Generally stated, the CGB department is committed to the generation and management of genetic information by approaches aiming at elucidating the connection between genes, protein and function.WiGID is a genome information database that is available through WAP (Wireless Application Protocol).Our version of WiGID is based on WML, PHP and PostgreSQL as a database server.One of the changes on the old WiGID application was the creation of a relational database with seven tables and one view, instead of the file that represented the database on the old version. We also changed the script language from python to PHP.The search engine ability has been extended with three new search alternatives for a user to choose from. Each choice leads to other, sometimes multiple choices.A GUI has been created for the administrator, to be able to insert information into the database.The structure of the search engine is primarily for narrowing down the search result on the phone display, thereby making the search efficient..

Denna projektrapport är avsedd att vara ett hjälpmedel för SiCell, en del av SciLifeLab Uppsala som ska bli Europas första plattform för enkelcellgenomik till hösten 2013. SiCell har bett projektgruppen om undersökningar gällande ett Laboratory Information Management System, LIMS. På svenska ett datahanteringsystem för laboratorier. Ett sådant system skulle kunna effektivisera SiCells verksamhet. Undersökningarna har resulterat i en kravspecifikation som ett LIMS för SiCell ska uppfylla och en sammanställning av tillgängliga mjukvaror som bäst uppfyller dessa krav.

During the last decade a new technique in animal breeding has developed called genomic selection. It is based on estimations of the effect from genetic markers on traits that are calculated in a reference population. By genotyping individuals, genomic breeding values can then be estimated without phenotypic observations. The aim of this essay is to investigate the response of genomic selection on breeding schemes for dairy cattle. The accuracy of the genomic breeding values is affected by the proportion of observations included in the validation set and how often the equation for estimating breeding values is reevaluated.