Detta arbete undersöker användningen av evolutionära algoritmer för framtagning och utvärdering av byggordningar i RTS-spel. Syftet var att undersöka om just evolutionära tekniker kan uppnå lika bra resultat som skriptade byggordningar då evolutionära tekniker oftast är billigare att utveckla.För att undersöka denna problemställning utvecklades en applikation med en experimentmiljö och en Artificiell Intelligens (AI) med evolutionär algoritm. Denna applikation och AI användes sedan för utvärdering av framtagna byggordningar.Resultatet antyder att evolutionära tekniker kan uppnå lika bra kvalitet som de skriptade byggordningarna.Något som krävs i detta arbete är fördefinierade skript för byggordningar för att köra evolutionen men något som skulle vara intressant att kolla på är coevolution. Med coevolution hade det varit möjligt evolvera fram byggordningar utan dessa färdiga skript genom att köra evolutionen mot individer i samma population..

Syftet med denna studie var att undersöka vikten av ett genetiskt föräldraskap hos par som genomgick infertilitetsbehandling i Sverige med donerade ägg eller spermier, samt att jämföra attityder till genetiskt föräldraskap mellan kvinnor och män samt personer med eller utan möjlighet till genetiskt föräldraskap. Denna delstudie ingår i ett större projekt som heter Långtidsuppföljning av IVF, ägg- och spermiedonation i Sverige. Den grupp som har undersökts i föreliggande studie är par som genomgått behandling med donerade ägg eller spermier under 2005-2006. Antalet recipienter i denna studie var 277 personer. Information har samlats in i form av enkäter.

Cardiomyopathy is the most common type of cardiac disease in the cat. Restrictive cardiomyopathy (RCM) is comparably uncommon and only a few studies have been conducted in this disease. The purpose of this study was to examine the presence and inheritance pattern of RCM in a family of Birman cats. The family comprised 177 known cats. 107 of these cats were examined by echocardiography, 23 of the cats died/were euthanized and a diagnosis could be established post mortem.

n this dissertation a comparison of two evolutionary methods for evolving ANNs for robot control is made. The methods compared are SANE with enforced sub-population and delta-coding, and marker-based encoding. In an attempt to speed up evolution, marker-based encoding is extended with delta-coding. The task selected for comparison is the hunter-prey task. This task requires the robot controller to posess some form of memory as the prey can move out of sensor range.

The ability of a dog to perform some kind of practical work, for example hunting or herding, depends among other things on its behavioural characteristics. In animal breeding it is not always easy though to select for behavioural traits. It may, for example, be difficult to identify traits that are not only heritable but also of importance for the dogs' ability to perform the practical work of interest. Moreover, it is often difficult to accomplish accurate measurements of behavioural traits. When selecting dogs for breeding, it is usually preferable to evaluate them using an objective and standardized bahavioural test, rather than results from field trials.

Hepatitis E virus, HEV, is a frequent causative agent behind, especially waterborne, infections in developing countries such as India. However, during the last years the number of non-travel-associated infections in industrialised countries, for example US, Germany and Sweden, has increased. The symptoms vary from mild with nausea to icterus and it can even be lethal. There are four different genotypes of HEV and many studies consider HEV infection to be a zoonosis. Scientists have by using phyloGenetic analyses found great Genetic similarity between strains isolated from humans, pigs and food, such as pork and liver, especially among viruses belonging to genotype 3.

The 22q11.2 deletion syndrome is a common Genetic disorder that affects for example the heart, palate, immune system and hearing and therefore affects a child?s development. The purpose of this study was to investigate the proportion of children (0-18 years) with 22q11.2 deletion syndrome who have a hearing loss. A retrospective study of 103 children diagnosed with 22q11.2 deletion syndrome was conducted by medical records. Of the 103 children, 51 were boys and 52 were girls.

 Genotyping can be used to link Genetic variation among individuals to certain diseases or conditions. Some known disorders and states that are dependent on single nucleotide polymorphism (SNPs) are lactose intolerance, venous thrombosis, hereditary hemochromatosis and the difference in sensibility among people to metabolise drugs.In this project a new kit, TaqManÒ Sample-to-SNP KitÔ for extraction of DNA and preparation of the extract for genotyping with real-time PCR and allelic discrimination, was evaluated. QIAamp® DNA Blood Biorobot® MDx Kit was used as the reference method.The purpose of the comparison was to find a method that makes DNA extraction from blood samples cheaper and faster, but with the same reliability as the reference procedure.The results of the evaluation showed a complete agreement of the genotype results between the methods tested, which means that the new method was as reliable as the reference method. The costs of reagents and material would be reduced with 52% if the new method is adopted, that alone would result in a cost reduction of 144 000SEK a year with a sample volume of 650 samples/month. The time for DNA extraction would also be reduced with the new procedure. .

Celiac disease (CD) is an autoimmune disease, induced by an immune mediated reaction in the small intestine after ingestion of gluten and related prolamines. There is a strong Genetic linkage and most important are the genes that encodes for HLA-DQ2 and HLA-DQ8. The European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) has developed new guidelines for investigation of CD in children and adolescents, which include genotyping for HLA-DQ2 and HLA-DQ8. Therefore, the clinical microbiological laboratory in Västmanland wants to introduce a method for analysis of these genes. Microarray is a newly developed method for determination of the alleles HLA-DQA1 and HLA-DQB1 that encodes for the ?- and ?-subunits of the HLA-molecules.

The Swedish institute of racial biology was the first of its kind in the world. The purpose of their activity was to gather information about the different kind of racial characters of the Swedish population. They did this by traveling around the country gathering pictures and statistic information. In 1958 it was decided that the institute was going to get integrated with the University of Uppsala and change its research focus to a more medical Genetic. Most of the research material also got integrated into the university?s library.The purpose of this paper is to find out how the institutes collection has been handled through the ages and if there have been any controversy or debate about it.

Celiac disease (CD) is an autoimmune disease, induced by an immune mediated reaction in the small intestine after ingestion of gluten and related prolamines. There is a strong Genetic linkage and most important are the genes that encodes for HLA-DQ2 and HLA-DQ8. The European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) has developed new guidelines for investigation of CD in children and adolescents, which include genotyping for HLA-DQ2 and HLA-DQ8. Therefore, the clinical microbiological laboratory in Västmanland wants to introduce a method for analysis of these genes. Microarray is a newly developed method for determination of the alleles HLA-DQA1 and HLA-DQB1 that encodes for the ?- and ?-subunits of the HLA-molecules.

Exoner är de sekvenser i DNA vilka rymmer koden för proteiner i människan och i alla andra organismer. Intronerna, vilka utgör utrymmet mellan exoner, består av ickekodande sekvenser och kontrollelement. Exoner tillhörande en gen måste inte alltid inkluderas i den slutliga mRNA produkten, alternativ splicing tillåter exkludering av vissa sekvenser och gör att en gen kan ha mer än en mRNA produkt, därigenom kan en gen koda för flera olika proteiner. Alternativ splicing är ett fält som snabbt utvecklas och dess relevans för många sjukdomar har blivit uppenbar. Detta arbete går igenom ett flertal av dessa sjukdomar för att sammanställa ny forskning och tydliggöra rollen av alternativ splicing i dem.

The aim of this essay is to try to gain understanding and to get a more profound knowledge of suicide. The questions at issue were 1) What empirical factors are mentioned in the research as possible to explain suicide. 2) Which theoretical perspectives are discussed in research concerning suicide. To answer our questions at issue we carried out a selective research overview with a qualitative perspective. The primary documents that has been the foundation of this essay is constituted by nine of the leading researchers publications in the area of suicidology.

Haptoglobin is an acute phase protein with important biological role because of its capacity to bind to haemoglobin. Haptoglobin exists in three major Genetic polymorphism types: Hp1-1, Hp2-1 and Hp2-2, the distribution of which has been associated with abdominal aortic aneurysm (AAA), an asymptomatic aortic disease common among men older than 65 years.    Five different electrophoretic methods were tested according to their ability to separate the haptoglobin phenotypes. The detection was based on a produced hemolysate of blood in which haemoglobin binds to haptoglobin thereby forming a complex that can be detected by specific haemoglobin staining using TMB-dihydrochloride and hydro peroxide as substrate resulting in an azure-green color of the bands. Samples from 15 patients who had suffered surgery for not broken AAA, that is more than5.0 cmaortic diameter, and 15 samples from matched controls were analyzed.    Among the five tested electrophoretic methods best migration and separation was seen on the pre-cast agarosgel Hydragel HR on the instrument Hydrasys. The other four methods gave less successful results.

The prime aim of this thesis was to investigate whether high or low iodine intake during certain periods of life was, or was not a strong risk factor for the development of canine lymphocytic thyroiditis (CLT). And secondly, if a high or low selenium intake in a combination with high or low iodine intake also may have an influence on that risk factor. To investigate this, a dietary questionnaire was sent out to dog owners. The dogs were selected from an ongoing Genetic study of CLT. The questions investigated brand and type of feed during different life stages (puppy, junior and adult) and also if there were any use of dietary supplements.