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1103 Uppsatser om Genetic disease - Sida 2 av 74
Emerging zoonotic viruses : what characterizes them and what are the risk factors for their emergence?
Emerging infectious diseases poses a great future threat, not only to humans but also to domestic animals and wildlife. Even though the majority of these infections only cause minor health problems, the relatively recent emergence of HIV clearly illustrates that the next major human pandemic may surface at any time. Regardless of what the name indicates, most emerging human pathogens are not believed to be recently evolved, but to have existed previously in the natural environment. Most emerging pathogens are zoonotic, i.e. able to infect animals besides humans.
Orala problem vid Parkinsons sjukdom
Parkinson's disease is a progressive degenerative neurological disorder. In Sweden there are 15 000-20 000 individuals affected by the disease.The aim of this study was to investigate the prevalence of oral diseases in individuals with Parkinson's disease. The material for the literature review was gathered in the medical database PubMed. Keywords used for the data research were ?Parkinson?s disease?, ?oral diseases?, ?dry mouth?, ?gingivitis?, ?caries? and ?periodontitis?.
Genetic diversity of Roseroot (Rhodiola rosea L.) from Sweden, Greenland and Faroe Islands
Roseroot (R. rosea L.) has gained more attention the last years, mainly because of its phy-topharmacologic properties. Even though many reports in roseroot have been published, only a few articles are dealt with the genetic diversity. The Nordic Genetic Resource Center has collected Roseroot material from Sweden, Greenland and Faroe Islands under different expeditions. The samples were analysed to study the genetic diversity study.
Evaluation of a new microarray method for genotyping of HLA-DQ2 and HLA-DQ8 for investigation of celiac disease
Celiac disease (CD) is an autoimmune disease, induced by an immune mediated reaction in the small intestine after ingestion of gluten and related prolamines. There is a strong genetic linkage and most important are the genes that encodes for HLA-DQ2 and HLA-DQ8. The European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) has developed new guidelines for investigation of CD in children and adolescents, which include genotyping for HLA-DQ2 and HLA-DQ8. Therefore, the clinical microbiological laboratory in Västmanland wants to introduce a method for analysis of these genes. Microarray is a newly developed method for determination of the alleles HLA-DQA1 and HLA-DQB1 that encodes for the ?- and ?-subunits of the HLA-molecules.
Alzheimers sjukdom : Närståendes upplevelser i samband med vården - En studie av självbiografier
Background:Alzheimer's disease is a disease that primarily affects the elderly but also younger people. Alzheimer's disease is a type of dementia which means that you get changes in the cerebral cortex and cells gradually die. The disease causes memory loss and things that were obvious before will be difficult for the sufferer. Alzheimer's disease also affects next of kin to a large degree; they will have to take a great responsibility. The next of kin are entitled to support from healthcare.Aim:The aim was to highlight next of kin' experiences of healthcare to their family members with Alzheimer's disease.Method: The study was based on narratives, which in this case means analysis of autobiographies.
Genetiska ultraljudsmarkörer : Hur bör information till blivande föräldrar i samband med rutinultraljudet hanteras?
Objective: The purpose of the study is to explore and illustrate how ultrasound midwives and medical specialist in obstetrics and gynecology believe the information given to parents about the genetic soft markers should be handled.Design: A quantitative questionnaire study with cross-sectional design. Participants: 44 ultrasound midwives and 37 medical specialists in obstetrics and gynecology.Findings: Most of the participants would like to inform before the ultrasound starts that they will be looking for genetic softmarkers during the ultrasound. Likewise the majority wanted to inform the parents about possible increases in the risk for chromosomal abnormalities based on findings on the routine ultrasound. There was a difference in frequency between those who responded that they would like to inform before the ultrasound that they will be looking for genetic softmarkers and those who responded that they believe the future parents wants information before the examination.Key conclusions: It could help health care professionals in their role as information providers if there were common recommendations for the information to be given to future parents about genetic softmarkers in connection with the routine ultrasound.
Livskvalitet och rehabilitering för män och kvinnor med diagnostiserad hjärtsjukdom : en litteraturstudie
The aim of the study was to describe how women and men with diagnosed heart disease experience their health-related quality of life and what differences there is between genders in their quality of life and also describe problems after receiving the diagnosis. The study also aimed to describe rehabilitation of patients with heart disease. The study was a descriptive literature study based on scientific articles. It emerged that both women and men with heart disease experienced lower quality of life compared to normative data. There was a significant difference between women and men both one year and three years after receiving the diagnosis heart disease, which showed that women experienced lower quality of life than men.
Förvildade husdjur : möjligheter och hot
Feral animal populations are distributed over many parts of the world and are often seen as a problem. Since they are a threat against other species, destroy farmlands and can spread dis-eases, they are often referred to as pests. Artificial selection has contributed to loss of genetic diversity in our domesticated animals. Feral animal populations are affected by natural selec-tion, which allows them to adapt to the environment. Their ability to adapt is a reason to see them as pests but can also be seen as an asset.
Att leva med en inflammatorisk tarmsjukdom
Background: Inflammatory bowel disease (IBD) is an umbrella term for ulcerative colitis and Crohn's disease. These are characterized by a chronic inflammation of the intestinal mucosa. Living with chronic illness meant that life changed significantly. Quality of life was affected for these individuals and was stressful in their lives. Aim: The aim was to describe the experiences of living with inflammatory bowel disease. Method: A qualitative literature review was chosen to analyze articles that were related to the aim of this study. Results: Based on the chosen articles five themes were created; Commuting between hope and fear, symptoms of the disease and medication become everyday focus, struggling with the new identity, desire to control the disease- do I control my illness or does it control me and social relationships are affected. Conclusion: Inflammatory bowel disease is a distressing disease and can cause limitations in social life due to lack of knowledge by others about the disease. The affected felt a loss of control in their life due to the difficulty in managing the symptoms.
International and national genetic evaluation of beef cattle : validation of national genetic evaluation models
After a workshop in Kuopio held in June 2006, Interbull decided to go forward with the development of a system for beef international genetic evaluation and a three year project called Interbeef was launched in June 2007. The participating countries are so far limited to Europe and the only trait evaluated at present is adjusted weaning weight (weight at 200 days). The results from a first international genetic evaluation have been shared with the countries but are not yet official. The evaluation is based on data from purebred Charolais and Limousin. To achieve good estimates of proofs in an international context it is important that methods for data validation and model selection are implemented.
KVINNLIG OMSKÄRELSE: Afrikanska kvinnors upplevelser av omskärelse efter flytten till västvärlden
Background:Alzheimer's disease is a disease that primarily affects the elderly but also younger people. Alzheimer's disease is a type of dementia which means that you get changes in the cerebral cortex and cells gradually die. The disease causes memory loss and things that were obvious before will be difficult for the sufferer. Alzheimer's disease also affects next of kin to a large degree; they will have to take a great responsibility. The next of kin are entitled to support from healthcare.Aim:The aim was to highlight next of kin' experiences of healthcare to their family members with Alzheimer's disease.Method: The study was based on narratives, which in this case means analysis of autobiographies.
FÖRÄLDRARS BEHOV NÄR BARNEN VÅRDAS PÅ SJUKHUS en kvalitativ litteraturstudieA CHILD´S STAY IN HOSPITAL ?FROM THE PARENTS` PERSPECTIVE
Background:Alzheimer's disease is a disease that primarily affects the elderly but also younger people. Alzheimer's disease is a type of dementia which means that you get changes in the cerebral cortex and cells gradually die. The disease causes memory loss and things that were obvious before will be difficult for the sufferer. Alzheimer's disease also affects next of kin to a large degree; they will have to take a great responsibility. The next of kin are entitled to support from healthcare.Aim:The aim was to highlight next of kin' experiences of healthcare to their family members with Alzheimer's disease.Method: The study was based on narratives, which in this case means analysis of autobiographies.
Kan grad av degenerativ hjärnsjukdom prediceras med hjälp av mått på kognitiv försämring?
Can degree of degenerative brain disease be predicted with the help of measurements of cognitive deterioration?Alzheimer?s disease progresses through nerve cell break down in the brain and the simultaneous deterioration of the individual?s cognitive function. This disease is common among elderly persons. This thesis examines if the level of deterioration of cognitive function is associated with different biochemical and clinical markers for degenerative brain diseases. In addition, this thesis examines if the level of decline in cognitive functions vary between groups with different levels of degenerative brain disease.
Kvinnors erfarenheter av att leva med migrän : En studie baserad på skriftliga berättelser
Background:Alzheimer's disease is a disease that primarily affects the elderly but also younger people. Alzheimer's disease is a type of dementia which means that you get changes in the cerebral cortex and cells gradually die. The disease causes memory loss and things that were obvious before will be difficult for the sufferer. Alzheimer's disease also affects next of kin to a large degree; they will have to take a great responsibility. The next of kin are entitled to support from healthcare.Aim:The aim was to highlight next of kin' experiences of healthcare to their family members with Alzheimer's disease.Method: The study was based on narratives, which in this case means analysis of autobiographies.
Genetic variation in local Swedish sheep breeds
Sheep have played a very important part in rural history. In Sweden there were many kinds of
small native breeds, kept for their meat and fleece. Women cared for the flock that often had
very little to feed on during the cold and sometimes harsh winter months. This meant that
these sheep over time acquired special phenotypic properties depending on the environment
they lived in, and easily fed compared to modern breeds kept for meat. Most of these sheep
have since become extinct.