Duchenne Muscular Dystrophy (DMD) is a hereditary X-linked fatal disease that affects 1 in 3500 male births. It is the most common kind of muscular dystrophy in children and leads to death in the late teens or early 20s for many patients. The mdx mouse is a model of DMD that can be used to investigate experimental therapies. Overexpression of a glycosyltransferase, CT GalNAc, in mdx mice has been demonstrated to prevent the development of muscular dystrophy. Overexpression of another glycosyltransferase, LARGE, is currently being investigated as a treatment for another group of muscular dystrophies, the dystroglycanopathies. In this study, we overexpressed LARGE in mdx mice in order to investigate its effect on the development of muscular dystrophy.

  The study aims to gain a better understanding and explore how a selected group (receivers) perceive two elected advertising images from Indiska and Vila and then compare their opinions to what Indiska and Vila themselves want to communicate. We base the study on theories of encoding / decoding, which deals with how the companies charge their advertising images with values and how recipients decodes these values.A qualitative study was carried out based on analytical induction (planning, collection and analysis). Through the analytical method of induction, we created categories based on the collected data and put them in relation to each other. The result showed that the overall impression of the images' and the context are of great importance for how our respondents perceive the advertising images. The overall impressions convey emotion that reinforces the expression and the message.

This study is an attempt to investigate religious perceptions and its development, function and connection to religious practise within the Swedish extreme metal scene. This is performed mainly by a qualitative method of investigation, studying lyrical content published on a number of extreme metal albums, thereafter relating the lyrical progression to the progession of the scene as a whole and also to the development of individual religious belief and practise.The lyrically expressed manifestations of religiosity within the extreme metal scene prove to be related to religious practise in some cases, most visibly in the Christian parts of the scene.The study also indicates that development of religious expression often is evident regardless of religious preference. This development also regularly relates to an increase in musical evolution and prowess often achieved with increased age and maturity.Musically and lyrically, the extreme metal scene displays transgressive attributes which assist both individual and group in the process of creating identity, meaning and individuality.Experiencing extreme metal, in concert or in the privacy of one´s own home, can be one way of perceiving spirituality in this modern age..

Tissue factor (TF), a 47 kDa glycoprotein, is the initiator of the extrinsic pathway of blood coagulation and consequently of the upmost importance when damage to blood vessel occurs. The source of TF in circulation has been investigated. However, the source of TF is still not clear. One theory is that platelets express and increases the expression of TF after stimulation and the aim of our report was to investigate whether platelets really are a source for TF in circulation.Using specific primers for TF mRNA, platelets in plasma from healthy volunteers and from patients suffering from cardiac infarction were analyzed by using real-time polymerase chain reaction (PCR). Gel electrophoresis was performed after amplification of TF mRNA to verify the results.The samples were negative for TF when using real-time PCR and the few positive all had cycle threshold (Ct) values above 35.

 Car seats for smaller children, offers very good protection incase of a collision. Unfortunately for the parents? sake , these car seats is heavy to handle outside the car. For example back and forth home and short errands around town. In other words, all those times when you decide to just take out the car seat and carry it instead of place the baby in a baby carrier.

During the last decade of the twentieth century both ?manhood? and gender studies seems to have undergone changes. With the field of masculinity and the critical studies of men, added as ?subsections? of broader gender studies, new knowledge has been produced to better grasp the production of gender and power relations of patriarchy. During the same decade as the ?metrosexual? first appeared of the urban stage, acts of homophobia and attitudes towards ?manhood? seems to have changed.

This thesis aims at examining to what extent a few, algorithmically very easily extractable document features can be used to classify electronic documents according to genre. A set of experiments is therefore carried out, using only 11 such simple features in an attempt to classify 84 documents belonging to electronic academic journals into three manually identified genres: table of contents, article, and review. The 11 features are also divided into three sets, containing metrics of words and sentences; punctuation marks; and URL links, respectively. The performance when using these sets of features is then measured with regard to classification accuracy, using a k-NN classifier, four different values of k (1, 3, 5, 7), and both leave-one-out and 10-fold cross-validation. Best results are achieved when using all three feature sets (i.e.

This Masters thesis concerns feature film services in Swedish public libraries. We have investigated the opinion of eight librarians concerning values and criteria for selection as regards film. The theory chosen comes from varied disciplines, for example sociology, adapted to our subject. The most important theories are Antonio Gramscis idea of hegemony, Herbert J. Gans concept of taste cultures and Carl Gustav Johannsens discussion about quality.

The purpose of this study is to gain a deeper understanding of women's violence against men in intimate relationships, get an idea of ??what forms of expression that this type of violence has and to highlight the men's experiences of violence.There is little scientific research in the field in Sweden. Crime Prevention Council has determined that eight percent of all complaints involving domestic violence in 2010, reported by men over 18 years. You can only speculate on how large number of unreported cases is among abused men. The international studies highlight that the abused men feel ashamed of having been subjected to violence by a female partner.I have been based this essay on two theoretical premises, Per Isdal theory of "violence perspective" and Elaine Bergqvist's definition of the suppression technique.The study was conducted through a qualitative content analysis.

In my degree project I have chosen to write about the social interactions in children?s play. Iwanted to study their free play and the time when their teachers tell them what to play to seewhat their social interactions look like. The purpose with my research is to study whathappens in the social interactions in their different playing situations.I performed three observations of the free play and three observations of the guided play at apreschool to study what social interactions that takes place in the different playing situations.What happens and what patterns can I find in their play.In my research I had some questions that this project rests upon:What happens in the social interactions in the different playing situations?How do the children?s different social interactions look?The children that I have observed showed me that when they are interacting they especiallyuse their cognitive abilities, because an interaction needs a certain mental development.

This is a study concerning the conventions surrounding death and it´s rituals during the latter half ofthe 21th century. The study´s main material is the official magazine of SBF - Sweden´s funeral association ? Memento. By studying the undertaker and the self-image of his services at an intervalof years from 1945 to 2005, one is able to notice certain changes of values concerning what afuneral, a chest and a tombstone really is ? or rather how the meaning of these symbols of death slowly shifts from the ?dignity? of death towards the self-expression of the individual.In the 1940´s towards the 80´s, there is much talk of giving the dead a ?dignified? funeral and burial, and this is how the undertaker defends himself against public critique of his or her´sprofession´s ?trade with death?.

The use of social media has increased considerably in recent years and has also caused some problems. It has been notable cases in the media where employees adversely criticized their employer on social networks, which subsequently led to the dismissal of the employee. The purpose of this study is to investigate an employee's right to express themselves about their employers in various forms but the main focus will be on social networks. The study investigates employees on both private and public sectors.Employees have a duty of loyalty to their employer, which means that they must be loyal to their employer and not deliberately harm them. The reason that employed comment his employer on social networks has its basis in that they also have freedom of speech and it is raised in such a case, a collision between their rights and responsibilities as an employee.The employees also hold a critique right entitling them to publicly criticize the employer and its activities.

Michelangelo Antonioni (1912-2007) belonged to a generation of filmmakers that breathed new life into cinematic expression in the annals of modern-day European film history. By employing his background as a documentary filmmaker, Antonioni used these skills to help establish his own particular style. There was a distinct evolution of style which progressed during his triology L´Avventura, La Notte and L´Eclisse, 1959-1962. This theises presents a comperative study between his earlier films in black and white and his first color film - Il deserto roso, from 1964. By observing color in relation to narrative, dialouge, acting and elements of mise-en-scène, I suggest different answers than those previously discussed among critics concerning this interrelationship.

The hotel is located on Skatholmen in the archipelago of Stockholm, Värmdö county. The hotel building has an open structure characterized by hospitality and the nature outside. The rooms have stunning views of the island landscape and lush forest. With biodiversity and valuable nature in mind, the building has been designed with a structure that should not be too intrusive in the surrounding landscape. The building is meant to blend into the dark silhouette of the island and to give a light footprint on the topography of the landscape.The use of well-chosen materials and similar design, both in plan and facade, creates a consistent building despite the building's somewhat playful expression.

Lucie Lagerbielke (1865-1931) is a fairly unknown writer who lived and worked in Stockholm. All her life she was writing with a strong aim to tell her truth and she had an aspiration to change the world for the better.  Her main points of views in her authorship were; oneness, the power of love, a belief in a supreme purpose to be served, religious mysticism and the interest in understanding and to prove the transcendent on a scientific basis. In my discussion I relate to Rita Felski and her expression the popular sublime, a term she applies to illustrate a sublime way of writing that was common in women popular fiction in the late nineteenth-century. This romantic literature with escapist tendencies was popular among the ordinary readers but very seldom met with success with the professional critics.Focus in this BA thesis is the spiritual Lagerbielke and in what way she wants to change the society. I have analyzed two of her novels, Daniel- ett lifsöde and En sällsam upplefvelse with intention to examine how she used her novels to plead for her cause.By making such an analysis I come to the conclusion that both her novels have the purpose to emphasize her philosophy of life.