Examensarbetet som utförts vid Jönköpings tekniska högskola har syftet att konstruera en audioförstärkare. Målet var att åstadkomma goda prestanda på den valda audioförskartypen. Den utvalda varianten utvärderas med avseende på dess prestanda. Audioförstärkaren bör ha följande egenskaper: En kanal med en uteffekt på minst 40W samt ett frekvensområde på 20Hz till 20KHz, utan att använda sig av integrerade komponenter. Temat för rapporten bygger på analysering av konstruktionskretsen och en detaljerad beskrivning av ingående delar samt jämförelse med andra kopplingar med liknande funktion.

I denna studie har förekomst av progesteronreceptorer i olika typer av primära juvertumörer undersökts med hjälp av immunohistokemi. Dessutom har tumörceller från carcinomcellinjen CMT-U27 odlats i olika cellodlingsmedium och exponerats för olika testsubstanser som binder till progesteronreceptorn (progesteron och RU486/mifepristone). Cellernas receptoruttryck och progesteroninnehåll utvärderades med hjälp av ELISA och tumörcellernas viabilitet analyserades med Colorimetric Cell Viability Test. Av resultaten framgår att samtliga undersökta primära juvertumörer uttryckte progesteronreceptorer. De odlade cellerna hade högre cellviabilitet när de odlades utan fetalt bovint serum (FBS). Efter exponering med progesteron minskade tumörcellernas uttryck av progesteronreceptorer, vilket hämmades av mifepristone.

Hemoglobin is an oxygen binding protein in erythrocytes. Hemoglobin is composed of four polypeptide chains. During the fetal stage the type of hemoglobin called fetal hemoglobin (HbF) dominates. After birth HbF is replaced by adult hemoglobin (HbA). HbF persists in concentrations less than 1%.

Man's life has changed in many ways since technology made it?s entry for public at large. In response to this change the science of human-machine interaction was invented. It has in turn evolved into human-computer interaction. With this science the focus is on the customization of the system for the actual person who will use it.The thesis has been implemented in a telecom company's development department.

The development of quantitative, real-time PCR (qPCR) combined with the mapping of the canine genome opens new possibilities in veterinary medicine. This method provides a quick and accurate quantification of the expression of a specific gene at a given point in time and thereby also information of how the gene expression for a certain protein is influenced by various conditions and diseases. One possible area of application is identifying bio markers for cancer. Recently the protein serglycin (the core protein of an intracellular proteoglycan) was found to act as a selective marker for the disease acute myeloid leukemia in humans (Niemann et al, 2007). Serglycin is produced by most hematopoietic cells, although mast cells account for the largest amount of serglycin.

Husqvarna AB uppmärksammade att det kommer införas nya miljöregler i Kalifornien gällande diffusionsutsläpp. De åkgräsklippare som går under namnet Rider och tillverkas av Husqvarna idag uppfyller ej dessa krav. Dagens bränsletank är tillverkad i plastmaterialet HDPE och avdunstande bränsleångor klättrar lätt igenom tankväggen ut i atmosfären vilket ej är tillåtet enligt de nya reglerna. Vi blev tillfrågade om vi kunde lösa problematiken och ta fram ett system som kontrollerar de avdunstade bränsleångorna och se till att detta system uppfyller de krav som ställs i Kalifornien. Som blivande ingenjörer tyckte vi att detta var ett passande examensarbete med många olika områden involverade som materialkunskap, tillverkningsprocesser, produktutveckling samt inblick i ett större företags arbete. Vi har med detta examensarbete tagit fram ett system som minskar det miljövådliga diffusionsutsläppet med cirka 90 %.

Background: Society of today is characterised by greater dynamics and a constant demand for innovation and fresh ideas. This development is often named "the new economy" or "the knowledge society". Independent of how one chooses to name this society, most individuals seem to agree upon the fact that knowledge grows more and more important. New competencies, such as new knowledge and new forms of organising, will be demanded for corporations to be successful in the future. In recent years it has become more common with corporations based on projects.

Preservation of cells and tissues by freezing at temperatures below 70°C has led to new possibilities for the storage of germ cells for fertility preservation. During the freezing process problems might occur, the greatest being ice crystallization which can cause membrane destruction and thus cell death. To minimize this risk, solutions that reduce the freezing point can be added to reduce crystallization and increase survival rates. These solutions are called cryoprotectants. The best method for freezing is still not known.The aim of this study was to analyze the effect of various parameters on the survival rate of human semen frozen with liquid nitrogen.

Denna studie avser att ta reda på om någon förändrad effekt kan fås gällande bränsleförbrukning och emissioner då dieselolja strömmar igenom ett magnetiskt fält innan det förbränns i en dieselmotor som driver en generator. Utrustningen som ger upphov till magnetfältet har tillhandahållits av ett kommersiellt företag. Studien består av två delar, en teoretisk del och en praktisk del. I den teoretiska delen presenteras tidigare vetenskapliga studier inom ämnet samt hur tillverkaren av utrustningen menar att tekniken fungerar. I den praktiska delen har tester gällande rökgasemissioner och bränsleförbrukning gjorts.

Developments in milk production are heading towards fewer but larger herds where the milking process is often fully automated. Automatic milking systems were launched in the 1990?s and in the year 2010 the Automatic Milking Rotary (AMR) was introduced. As a rule there are no supervision personnel present during the milking event in systems with automatic milking. This means that there is a risk that cows can be incompletely milked in one or more udder quarters, for example if the robots fail in attaching the milking cups or if the cow kicks off the milking unit.

Exoner är de sekvenser i DNA vilka rymmer koden för proteiner i människan och i alla andra organismer. Intronerna, vilka utgör utrymmet mellan exoner, består av ickekodande sekvenser och kontrollelement. Exoner tillhörande en gen måste inte alltid inkluderas i den slutliga mRNA produkten, alternativ splicing tillåter exkludering av vissa sekvenser och gör att en gen kan ha mer än en mRNA produkt, därigenom kan en gen koda för flera olika proteiner. Alternativ splicing är ett fält som snabbt utvecklas och dess relevans för många sjukdomar har blivit uppenbar. Detta arbete går igenom ett flertal av dessa sjukdomar för att sammanställa ny forskning och tydliggöra rollen av alternativ splicing i dem.

Sweden is dependent on secure sea transport. Shorter disruption of imports of fuel and crude oil can be managed with an emergency stock, but a prolonged halt in imports creates problems. For industry, the vulnerability is greater. Fragmented production chains in combination with expenditure reductions in inventory causes a dependency on proper transport of intermediate goods in the manufacturing industry. A lengthy disruption thus involves disruption of production for both domestic consumption and for export goods containing imported parts.In order to secure shipping routes with a limited number of vessels, Mine Counter Measures (MCM) capacity is required, and according to the Armed Forces, developed with new sensors and autonomous vehicles.

When different type of programs are developed one wants to make these adjustable to future changes and requirements. It must be done a good design of the program from the beginning to make it possible to continue development of it without having to redo big parts of it to high costs. In the area of object orientation there are design pattern, which can be used to design systems that can be adjusted to new changes in an easier way. I have in this thesis chosen to take a closer look at how to design a program that sends SMS to cell phones through a system of an operator. One requirement on the program is that it has to be possible to change what operator to send though in an easy way.

This examination project has been performed in collaboration with Husqvarna AB, one of the world?s leading manufacturers of both commercial and professional garden products such as chainsaws, trimmers and lawnmowers. Husqvarna AB always strive to develop and improve new and existing products and components to ensure an attractive product and a competitive position on today?s market One of these components is filled balances. This is a component unique to the company and is one of the parts in their fuel-powered chainsaws.

The dry out criterion (MCPR) has been calculated for the most limiting H2-events for Forsmarks unit 2 and 3, at operating points that are normally not analyzed before each cycle. The operating points that normally are regarded as the ones with the lowest margin to dry out are the ones where the thermal power is the highest at agiven recirculation flow. This report shows that this is not the case for Forsmark 3. MCPR-values at partial power operating points are higher for the limiting case inside rather than on the boundary of the region of operation. It is therefore recommended that the method for determining the dry out criterion for Forsmark 3 is revised to account for this effect.