The dairy cow?s ability to resume estrus after calving and to conceive is affected by their metabolic status after calving. For high yielding cows there is a high risk that the feed intake will not be sufficient to cope with the increased energy demands after calving, and the cow will end up in a state of negative energy balance. Energy balance can be measured in various ways, for example by body condition score or by plasma concentration of several metabolic hormones and metabolites. After calving, endocrine pathways stimulate tissue mobilization; insulin signaling is blocked, the concentration of insulin-like growth factor-1(IGF-1) and leptin decreases, and the concentration of growth hormone (GH) increases.

Handling, loading, transport time and unloading in connection to transport of farm animals affect animal welfare. Induced effects include both psychological and physiological stress responses in animals. The physiological parameters may be measured through blood analysis while behavioural changes often manifest themselves through increased vocalisation, escape attempts and apathy. Physiological parameters are additional parameters of importance when measuring animal stress responses. The handlers behavior during transport has been shown to have major impact on animal welfare and the quality of meat. Animal friendly handling and driving of animals create a more manageable work environment for the handlers. To further increase animal welfare in connection to transport, stables should be built with well adapted drift passage and ramps on the transport vehicle.

Today the individual ventilated cage system (IVC-system) is the most commonly used system when housing rodents. IVC systems are designed to control both supply and exhausted air at cage level, as well as temperature and relative humidity in the cages. This creates an optimal environment for the mouse and at the same time a protection against the risk of cross-infection between cages and the outside environment. The aim of this study was to evaluate the health and welfare for two different strains of laboratory mice (NMRI nude mice and C57BL/6NCrl mice) in three different kinds of IVC-systems; Arrowmight, Allentown and Tecniplast. 108 mouse pups from each strain (in total 216 mice) were selected after weaning at an age of three weeks and tested during 5 weeks.

In many biomedical contexts, e. g. when evaluating hearing disorders, the data obtained can be described as pairs (x1, y1), ?, (xn, yn) where x is a quantitative variable and y a 0/1 variable whose probability of taking the value 1 is a monotonic function of x. One way of analysing such data is to perform probit regression; thereby two parameters, b0 (= the constant) and b1 (= the slope) are estimated; the interest centres around m = -b0/b1, i.

Rabbits carry a high risk of anesthesia related death. This study was part of a project to develop a form of total intravenous anesthesia (TIVA) with minimal effects on cardiac, respiratory and metabolic parameters. In the study, TIVA with sufentanil and midazolam (group TIVA, n=9) was compared with inhalation anesthesia with sevoflurane (group SEVO, n=9) in female rabbits undergoing surgery (ovariehysterectomi). All rabbits were pre-medicated with medetomidin and carprofen before anesthesia induction. Anesthesia was induced with TIVA (2.3 ?g/ ml sufentanil, 0.45 mg/ ml midazolam) at a rate of 4 ml/ kg/ h and the mean induction dose was 0.4 ?g/ kg of sufentanil and 0.1mg/ kg of midazolam.

As the number of people owning a smartphone rapidly increases so too does the opportunity for various researchers to exploit this technology. The possibility to recruit people to participate in research studies improves and with it the chance to get more diversified target groups in terms of age, socio-economic status, geographical location, etc.In this essay, I argue that the opportunities smartphones offer in terms of collecting research material is vastly underestimated in several areas, bearing in mind the advantages they present. In order to support my argument, I shall present a case study carried out in the research area of happiness ? an area where the use of smartphones has provided significant opportunities for research.In order to gather the advantages and disadvantages of this method of study from the participants? perspective, I have followed a happiness research study which is a collaboration between Umeå University and The University of Stockholm. I have interviewed the participants of this study in order to assess the advantages and opportunities that smartphones offer in research programs.Overall, the participants? opinion of this research method was generally positive and it was considered to be quite easy to participate in the study and respond to the questions asked.

The wide distribution range of our boreal pine (Pinus sylvestris L.) provides a great variation in growing conditions and climate/weather factors that influence the wood development of the trees. A great number of extensive studies have been conducted over the years in order to clarify growth trends of this and other species over more or less wide-ranging areas. In this thesis effects of weather factors were instead compared between different forest stands from the about same geographical location. The effects of precipitation, temperature and frost on the year ring characteristics of pine were studied in the research forest of Svartberget Vindeln, in northern Sweden. The stands differed in site index and silvicultural treatment; fertile ? high stem density, fertile ? low stem density, poor ? high stem density and poor ? low stem density.

In the next few years the pollutants loading at the Slottshagen wastewater treatment plant in Norrköping is going to increase due to the reason that one of the waste water treatment plant in the district will be shut down.A survey of how these different pollutants are divided in the treatment process is therefore necessary for mapping out both the loading and treatment efficiency.This can be achieved by studying mass balances.Mass balances were carried out for the water treatment process for the mechanical/chemical,biological and the chemical stage.The mass balance studies show that the treatment efficiency was very good. However in order for the mass balances to be quite consistent and to ensure complete coverage of results and conclusions i.e. more reliable results, sludge samples should be collected and taken at different times per day and the influent rate should be investigated.In this work mass balance has been set up in order to illustrate and identify the factors that should be considered and taken care of for further estimation using mass balances in the future. Furthermore this survey results in a calculating model for the mass balances at thisplant.This calculating model is used as a tool to facilitate future calculations for mass balances for the water treatment process at Slottshagens wastewater treatment plant.Moreover it provides a basis for carrying out further estimation of the treatment process in the near future.In this project the importance of some operating parameters was also taken in consideration.This calculating model can be modified so that calculations of such operating parameters i.e. sludge loading and sludge age can be easily performed.Such information can be used further to evaluate different operation alternative in order to ensure an optimal use of the treatment process with in the plant..

This thesis describes the redesign ofequipment designed for drying bags thatis used in Fresenius Kabis´manufacturing of their nutritionmedicine in Uppsala. The need of thistask arise during the start of thedevelopment of a new packaging line werethis equipment were meant to be used. Anevaluation of the bagdryers capacity andcapability was necessary.The work started with gathering ofinformation from suppliers of the usedcomponents and from the responsibleengineers for this equipment. Aneducation to learn how the equipmentworked and how to operate it were taken.That was followed by the creation of astudy plan were the tests were plannedto test different parameters effect onthe drying result and to see if thebagdryer managed to handle the bags ofthe correct format in the pace that theequipment should be designed for.The test results detected a need ofdesigning a unit with a function thatholds the bags in place while passingthrough the dryer in order to attainhigh quality results. The results werelater used for optimization of thedesign.

Gene technology has become more and more attractive in plant breeding during the last twenty years. This is probably because it can readily improve the existing commercial cultivars that have only one or a few drawbacks by modifying one or a few genes without changing the main genetic constitution. In this regard, gene technology is more effective than conventional breeding.The aim of this project was to analyze the fruit quality of the non-transgenic apple scion ?Jonagold? grafted on non-transgenic and rolB-transgenic apple rootstocks. The rootstocks used were M9-rolB1, M9-rolB2, M26-rolB and non-transgenic controls M9 and M26.

Methadone is frequently used as an analgesic drug for dogs although there are very few studies describing the pharmacokinetics of methadone in this species. In man methadone has a long half-life and there are considerable differences in pharmacokinetics between individuals. The dose interval is lengthened when the drug is used fore longer periods of time due to prolonged half-life. Therefore the drug dose must be adjusted individually. The purpose of this study was to study the fundamental pharmacokinetics of methadone in dogs, and to find an optimal drug dosage.

This thesis work resulted in a template for how the thermal spray process can be controlled through robot programs. The robots today and their programs need to be replaced, therefore a new structure which can be matched with the new robot systems is needed. The work is limited to only concern structured programming on the new robots on Thermal Spray Centre (TC) with the programming language Rapid. The basic data for the program was retrieved from interviews with concerned personnel at TC, from studies on process parameters for thermal spray and from existing specifications at Volvo Aero Corporation (VAC). The thesis work briefly describes the process thermal spray and the four methods used at VAC.

This masters thesis concerns a modeling project performed at Volvo Technology in Gothenburg, Sweden. The main purpose of the project has been to develop a physical model of the climate in construction vehicles that later on can be used in the development of an electronic climate controller. The focus of the work has been on one type of wheel loader and one type of excavator. The temperature inside the compartment has been set equal to the notion climate. With physical theories about air flow and heat transfer in respect, relations between the components in the climate unit and the compartment has been calculated.

Background: Examinations with the intent to assess neurological functions and level of conciousness are common in neurocritical care, but the effect on the patient is not entirely researched.Aim: The purpose of this study was to describe the patient?s situation at the neurological wake-up test concerning the environment, nursing interventions and the possibility given the patient to become awake, and if these conditions affect the outcome of the wake-up test.Methods: A quantitative observational study took place at a neurocritical care unit, where 20 patients were observed from interruption of sedation to the neurological assessment, which was performed by a neurosurgeon or a specialized critical care registered nurse. Nursing interventions, environmental factors and physiological parameters were documented.Result: Twelve intervention varieties to control patients? physiological parameters were used. CPP > 80 mmHg was found in 90 % of observations.

The main purpose of this thesis has been to find a way to evaluate the soil parameters for the Total sounding method (TS), such as the inner friction angles and settlement modules. This study only includes an analysis of soil profiles from the Stockholm region. The chosen location for the study is a proposed residential area east of Igelstaviken in Södertälje. Presently, the subject plot is located in a residential area and is also adjacent to a school area.Total sounding is originally a Norwegian soil testing method. The differences between the sounding methods (weight-, ram-, CPT-sounding) are for instance how the sound is driven into the ground and what kind of parameters that are registered.