Vectors based on lentivirus backbones have revolutionized our ability to transfer genesinto many cell types. Lentiviral vectors integrate into the chromatin of target cells and do not transfer any viral genes causing vector replication. Both of these features arecommonly used in gene therapy and have been used clinically in individuals sufferingfrom cancer, infections and genetic diseases. It has been discovered that T-cells can be genetically modified to be used as effective weapons against cancer: therefore virus mustbe produced to deliver the gene of interest into the T-cells. In this project, lentiviralvectors have been produced to transfer the gene coding for a chimeric antigen receptor(CAR) which is directed to CD19 on B-cells.

The aim of this Master?s thesis is to examine how the introducing of municipal library plans has influenced some compulsory schools in Malmö. I wanted to know if the library plan is a possible way to improve the quality of the school library. Through qualitative interviews with four school librarians and four headmasters, I investigate their knowledge of the library plan and their opinion of the possibilities to realize the directions of the plan. The theoretical framework is based on a model of organizational culture by Bakka, Fivelsdal and Lindkvist.

There are several methods avaliable to find areas of interest, but most fail at detecting such areas in cluttered scenes. In this paper two methods will be presented and tested in a qualitative perspective. The first is the darg operator, which is used to detect three dimensional convex or concave objects by calculating the derivative of the argument of the gradient in one direction of four rotated versions. The four versions are thereafter added together in their original orientation. A multi scale version is recommended to avoid the problem that the standard deviation of the Gaussians, combined with the derivatives, controls the scale of the object, which is detected.

This thesis aims at exploring a national collaborative gateway-service, PictureAustralia, hosted at the National Library of Australia. This will be done by means of investigating some underlying principles for descriptive standards and conventions as of the library discourse which is the objective of bibliographic control and access. The reason to do this is to bring some main features of these principles into the context of a cross-institutional cooperation between libraries, galleries/museums and archives in a picture database service. The attention will lay on the objectives of what functions the system is designed to perform to give access, as defined by Elaine Svenonius in the Intellectual Foundations of Information Organization 2000, and how these objectives will affect this particular database-service collocating performance, which is a system- and logical approach. Though, this study will be done in an explorative and qualitative way, by a case-study, which is to examine some sample metadata records emanated from different institutions in this project.

The increase in sales of the so called smart phones has meant that there has also been a requirement to determine new applications for which they are suitable. One of the largest platforms for smart phones is Android and the task of this thesis is to develop an application for a company that wishes to create interactive radio for the Internet. In addition to ordinary radio features, the company would like the application to be able to present images and a small web page called Canvas. The overall aim ,of this thesis, is to build a fully functional media player that is compatible with the majority of the commonly used Android based mobile units. To fulfill the overall aim, nine explicit goals were targeted.

The purpose of this essay is to examine at how to portray characters in the stories and narratives which depicts one of these children's books and if they really have something to ethnicity and its identification to be done.The Research questions is: What are the different identification markers given, to the reading child in the books, which might indicate that the story depicts people of different ethnicities? How are the characters portrayed in the story and which role is assigned to the main character? What story is portrayed and is it relevant to an identifier can occur?The conclusions of the five children's books shows that it is important with identifications markers, to show that there are different ethnicities. For example the analysis revealed the specific features of the illustrations and how the books portrayes someone with a different ethnicity and cultural background as something exotic.In the texts, the analysis showed how it occurred ethnic differences, by explicitly demonstrating differences between the characters. It was found that the characters were produced mostly as good, happy, curious, suspicious and unsympathetic. Common to all the main characters was that they had been placed, in one for them unusual context and that they were trying to assimilate to the new situations.Depictions consisted of realism and fiction.

This study is about the work around festivals and traditions that takes place in multicultural preschools. The purpose of this study is to describe and reflect upon the work around festivals and traditions in multicultural preschools from the view of five preschool teachers who are active in their profession.  The purpose is also to investigate which festivals and traditions that are given attention at preschool and for what reason according to the preschool teachers.The method of research chosen in this study is qualitative in the form of individual interviews with the intention of obtaining and interpreting the descriptions and reflections of the informants around the subject. The results will be analyzed from an intercultural perspective.The results show that all investigated preschools celebrate the traditional Swedish festivals Christmas, St. Lucia?s day, Easter and Midsummer, and that these festivals take up lots of space in terms of time and labor.

The aim of this thesis is to investigate the attitudes of librarians towards young people's approaches to libraries and reading. The study also includes statements of the young as regards their own library usages and reading habits, as well as the attitudes of youth leaders. The latter are compared to the statements of librarians, and serve as referential frameworks. 28 interviews were performed, of which 22 with young people. The interviews and the following discussion were based on five themes; the library as a room, usages of the library, reading habits, the library as an institution, and library changes and developments.

Purpose/Aim: To find power structures within the blog network.Material/Method: Using keywords to find all available blog posts about the National Defence Radio Establishment from the blog search engine Twingly, and thereafter using the same blog search engine to find inlinks from other blogs, to those posts. The data is set into the context of the small-world networks models of Duncan J. Watts and rich-club models of Sergi Valverde och Ricard V. Sole.Main results: 5183 unique blogs have written about the subject in 22779 blog posts to which 28128 inlinks from other blogposts are made. Just over one fifth of the blogs are linkted to each other in one big network, where the remaining blogs stand without any ingoing or outgoing links.

The purpose of this Masters thesis is to examine literature on current media events. We see a close relationship between this literature and the media society where we relate Manuel Castells theory of the network society. In this thesis we have chosen books which give different views on three major media events in Sweden: 1 the assassination of Anna Lindh, the former Swedish Minister for foreign Affairs; 2 the Knutby murder and; 3 the Tsunami disaster in Southeast Asia. These books combine fact and fiction in their writing which in media science is called faction. This form of writing has similarities to genres like new journalism and documentarism and can be problematic for the reader in terms of genre expectations because of the mix of fact and fiction.

The purpose of this study was to investigate how Islam and Muslims are portrayed a) in results from studies on Swedish teaching materials, and b) in articles in Swedish media newspapers. The study was conducted through two separate studies. In the first study, five previous research reports on how Islam and Muslims are portrayed in Swedish teaching materials were analysed in order to discern the main results regarding the portrayal of Islam and Muslims. In the second study, newspaper articles from 11 Swedish newspapers were analysed in order to discern which central themes emerge in the description of Muslims and Islam in said newspaper articles, as well as which properties and features are attributed to Muslims and Islam in the articles studied. In both studies, the data was analysed inductively through a qualitative content analysis.

Street art can be defined as an artistic expression, often anonymous and illegal, which is constructed in the public environment. The purpose of this essay is to provide a broad and balanced picture of what street art can mean. The aim is to examine street art as a phenomenon. What features has the phenomenon and in what ways is it important for the creators, spectators and place? This paper focuses on graffiti.

SAAB Aerotech division FGR in Arboga builds and develops equipment and components used in both military and civilian applications. To build a test system for a specific project that SAAB is responsible for requires a simple signal generator that can provide a pulse modulated signal. The need to buy a new advanced signal generator for example from Agilent is not as profitable as the instrument is expensive and contains features that SAAB does not require in their applications and test systems. That was the reason why SAAB offers two students a thesis where the goal is to construct a signal generator in accordance with what SAAB requests.This thesis contains several different phases. The first step was a meeting with our supervisor Mats Bergman and by reading the data sheets for components to be used in the project, with these information and specifications that we have received from SAAB we started to construct the signal generator.What we did during the construction work was to simulate and draw a schematic to be able to design the circuit board.

Vi har i en tidigare kurs genomfört en uppgift innehållande bråk, då vi upptäckte att elever hade svårt att lära sig framförallt sammansatta bråk. Vi blev intresserade av att ta reda på hur man skapar förutsättningar för att eleverna ska lära sig bråk, vilket är denna studies syfte. Studien syftar även till att upptäcka vilka aspekter som är kritiska för att lära sig bråk samt ta reda på hur dessa kan varieras i undervisningen vid elevernas lärande av bråk.I studien används en learning study som kan ses som en typ av aktionsforskning där lärare forskar i sitt eget klassrum. Inom learning study används variationsteorin som är en guidande princip för att förstå och skapa förutsättningar för lärande. Lektionerna som genomfördes av oss, blivande lärare, vid tre olika tillfällen videofilmades.

I approach the subject of adult readers of young adult fiction through an analytical framework influenced by Cultural Studies, implicating that young adult fiction is caught up in a system of distinction between popular literature and high literature. I contrast this with theories that suggest that there has been a loosening of this hierarchy and that they now coexist, even borrowing features from one another. I also examine questions of ideology, namely the ideology of mass culture, the ironical attitude and the ideology of populism. I also use Andreas Huyssen?s theory of mass culture as a woman, seeing as popular literature often tends to be categorized with feminine traits.