Mast cells have for a long time been known to accumulate around tumors (Maltby et al., 2009). Studies show that they may be important and sometimes essential in tumor angiogenesis, tumor growth and metastasis of tumors (Soucek, et al., 2007; Xiang et al., 2010). In an expression array study (Wensman et al, submitted manuscript) performed on mouse mast cells exposed to tumor conditioned medium, the gene 4-1BB was among the most up-regulated genes compared to control medium. 4-1BB codes for a membrane receptor protein of the tumor necrosis factor superfamily and has been shown to be important in T cell regulation in tumor diseases. This study was performed to investigate if human mast cells up-regulate 4-1BB when they get exposed to tumor conditioned medium.

This masters thesis is a study of how the expression quality literature is used in widespread newspapers and magazines. Wittgensteins idea of language games is used as a theoretical starting point. The analysis of 37 articles draws a picture of five language games that are called; the taking over, the polarising, the example giving, the gender critical and the ironic language game. The expression that quality literature is most often put in relation to is popular literature. The line between the two is sometimes distinctly drawn in the articles and sometimes quite vague.

The aim of this thesis is to analyse the possibility to identify the FRBR entity expression from existing catalogue records performed within the context of Swedish cataloguing rules. The empirical study uses a sample of records from the catalogue within the library at the University College of Borås. To begin with, the thesis reports some of the earlier discussion about the FRBR model. That gives an understanding of which problems the model has and justifies the study?s delimitation towards expression.

Social media has recently expanded dramatically, as more people are using different media such as blogs, Facebook and Twitter, to express their opinions. This increases the possibilities to spread information and an unclear legal regulation in this area can create adverse consequences. Freedom of expression is a constitutional right, which forms an important cornerstone of a democratic society. Public employees? freedom of communication means that they can submit information to the media, without fear of reprisals from the authorities.

Abstrakt All around the world there are a lots of people that suffers from chronic pain. One great factor for the devolopment of chronic pain is the phenomen fear-avoidance/kinesophobia that appear to have negative effects on rehabilitation of chronic painproblems. The aim of the present study was to describe and identify how patient that took part in a rehabilitationprogram in year 2004 and 2005 with focus on behaviourchanges estimate their fear-avoidance/kinesophobia and examine if there was any changes estimate fear-avoidance/kinesophobia respectivly before and after and respecivly before and 12 month after the rehabilitationcourse. The study had a describing prospecitive design. Data was collected by the Swedish version of Tampascale for kinesophobia.

This is a bachelor?s essay in the landscape architect programme in Alnarp. The purpose of the essay is to describe discussions about security in planning contexts in Sweden. Written material from three levels of the discussions has been studied: Swedish research, governmental directives and practisers. I have tried to obtain a variation in types of material.

When children are hospitalized they will face a new and unknown environment. Many children experience this situation as stressful and with fear. It is important that the nurse is aware of this fact in order to facilitate the hospitalization for the child. The purpose of this study is to investigate the fear that children feel when they are hospitalized, and to investigate the meaning of being well prepared for clinical examinations and procedures. The method used was a literature review.

Syftet med denna enkätstudie var att jämföra två olika förklaringsmodeller för tinnitusbesvär; fear avoidance och acceptans. Förutom att undersöka sambanden till tinnitusbesvär, testades även modellerna mot utfallsmåtten tinnitusvigilans och livskvalitet. Då nivå av depression och ångest är kända prediktorer för tinnitusbesvär, användes de som kontrollvariabler. Även processerna mindfulness och värderad riktning testades. Deltagare i studien var 362 patienter med tinnitus som någon gång mellan åren 2004-2011 varit i kontakt med Öronkliniken Hörselvården vid universitetssjukhuset i Linköping.

There is an expression called ?grief of climate? that refers to feelings of powerlessness and heaviness related to the environmental problems of today. A feeling that every move we make has bad consequences for nature. This essay is an investigation of how art in general and jewellery art in particular can be a way of discussing and visualizing current environmental problems and the complex relationship between human and nature. I am discussing how artworks dealing with a dark and dystopian picture of the relation can be seen as the memento mori of our time.

The purpose of the following essay has been to identify four men?s momentums of their volunteer access to treatment for their disruptive gender-based violence. The questions that have been asked in the entrance of this field have been divided into the following questions: (i) is it possible to identify the processes of change that leads to turning points into the interviewed men's treatment of violence, (ii) how do the interviewed men, themselves, reflect on their turning points into treatment, and (iii) are there other, implicit, interpretations and analyzes of men's access into treatment that I can discern in their stories? As a point of departure of the analysis one theoretical perspective has been used to explain and analyze men?s access to treatment, the sociological life course perspective, focusing on the concept of turning points.The method to approach this field has been qualitative interviews with a life story oriented approach which means that, focus has been to let the four interviewed men describe their lives from early childhood to their adulthood and from their histories identify contingent processes to their access of treatment. The study resulted in a division of two parts, one part consisting the processes that have been identified by the men?s stories of present tense of violent outbursts.

Introduction The genetic skin disease epidermolytic ichtyosis is caused by mutations in either keratin gene 1 or 10 and leads to blisters and hyperkeratosis of the epidermis. At cellular level the disease is seen as aggregates in the keratin filaments. Since medicines are hard to investigate and produce mainly due to lack of reproducible model systems, there is no good treatment available for this disease today. In this article we describe how an in vitro model consisting of cells from a stable cell line transfected with expression plasmids to mimic patient cells, may be a possible alternative for screening compounds for therapies. The first step was to generate an expression plasmid required to complete the in vitro model.

The purpose of this study was to examine young women?s perception and fear of sexual assault. An additional aim was to analyze the women?s view on guilt and responsibility in rape related questions. Two focus group interviews were executed with undergraduate women aged 22-32 years.

In this essay, I want to achieve an accessible and applicable entrance to Alexander Technique as a method for learning to use the body in such a way as to allow emotional expression in music. It is necessary to see the real need of Alexander Technique for the active musician, and therefore important components of music-making will be presented. These components are presented from an Alexander-perspective in order to produce a clear picture of the method of application.The prerequisite for emotional expression in music is musicians and music listeners with the ability to generate, and respond after emotional impressions. Alexander Technique provides an approach to make it easier for musicians, especially guitarists, to express emotions in a performance situation.After years of practice and obtaining musical knowledge and practical skills at the instrument, it is common that muscle tension and ingrained patterns contribute to limited expression. Muscle tensions arising from pressured situations such as auditions, competitions and concerts.

Aim: The aim with the thesis was to examine elderly peoples? motives towards physical activity. Method: A qualitative approach has been adopted with a purposive sampling procedure. Four half structured interviews have been conducted using a thematic interview guide. Results: The fear of being overweight and not being able to take care of themselves were announced as important aspects, since it motivated them to perform physical activity.

In couples diagnosed with unexplained infertility, the woman has normal ovulatory cycles and no organic pathology, and the man has normal semen. The period during which the implantation of an embryo can occur is defined as the window of implantation (WOI). For infertile women, disturbances in the endometrium maturation are hypothesized to impair the uterine receptivity for embryo implantaition. However, there are still no methods found to predict endometrial receptivity.Hemoglobin related-proteins hypothesized to be involved in embryo implantation have been found in the endometrium in both fertile and infertile women. The aim of this study was to determine whether there were differences in the expression of hemoglobin-related proteins, hemoglobin-?, cytoglobin, fetal hemoglobin and haptoglobin in the endometrium of fertile and infertile women.