Alternative splicing is a process that partly rejects the common definition of a gene ? that one gene codes for one specific protein. By variable combination of coding regions (exons) and exclusion of non-coding regions (introns), formation of several different mRNA-transcripts, and consequently several different proteins, can derive from the same gene. Alternative splicing is an important condition for the development of complex life forms, but it is also a highly sensitive process and inaccurate splicing is the cause of approximately 15 % of mutations that cause genetic diseases. This article presents four genes, BRCA1, BRCA2, ER? and ER?, and inaccurate splicing of these genes increases the risk of developing cancer, particularly breast cancer and ovarian cancer.

Syftet med studien är att utforska och utveckla kunskap om vilka beskrivningar av dyslexi som diagnos professionella med specialpedagogisk kompetens ger, samt deras upplevda erfarenheter av att utreda dyslexi.Metoden för insamling av data har varit intervjuer av specialpedagoger verksamma i två kommuner. Materialet har sedan analyserats och sorterats tematiskt.Resultatet av studien är att dyslexiutredningar utförs på olika sätt i olika kommuner beroende på hur man valt att organisera det och olika organisationsformer kan fungera bra. Deltagarna i studien använder LOGOS som en bas när de utreder dyslexi och deras erfarenhet är att det är en bra grund att utgå ifrån. Utöver det används intervjuer och observationer som utredningsmetod. Deltagarna anser inte att det viktigaste med utredningen är om eleven uppfyller kriterierna för dyslexi eller inte.

This is a case study on the functioning of political parties and the aim was to explain ?how? and ?why? the Swedish social democratic party changed their policies in the Middle East politics. I wanted to explain this process of change by using Angelo Panebianco?s framework for the analysis of political parties. Angelo Panebianco´s hypothesis is that all parties must be viewed as organizations to understand their functions.

Etiska aspekter av vårdyrket spelar inte en framträdande roll i sjuksköterskeutbildningen. Etik är den teoretiska referensramen för ett korrekt moraliskt handlande och sjukvård handlar om att ge rätt omvårdnad till en individ i behov av detta. När moraliska värderingar och verkligheten kolliderar kan en konflikt uppstå, vilket i sin tur kan leda till moralisk stress. Psykisk ohälsa har på senare tid ökat bland sjukvårdspersonal som en direkt följd av moralisk stress. Syftet med denna empiriska enkätstudie är att undersöka i vilken grad undersköterskor och sjuksköterskor upplever moralisk stress i det dagliga arbetet.

Background: According to the Swedish Social Board induced abortions are increasing in the modern day society. Nurses who work with in the gynecological department can come across patients seeking care for an induced abortion.Theoretical framework: The findings of the study will be discussed in relation to Peplau's nursing theory, ethical concepts and nursing concepts.Aim: The aim of the literature review was to illuminate the experiences of nurses working with induced abortion.Method: A systematic literature review with an inductive approach was chosen. The findings are based on seven qualitative and two quantitative studies. The articles were assessed through two different modified templates based on qualitative or quantitative design.Findings: Nurses and midwives experienced their work with induced abortions as emotionally stressful. However, it was highlighted that all women have the right whether to choose abortion or to proceed with the pregnancy.

The purpose of this master thesis is to understand how busy moms experience their grocery shopping trips and the in-store environment. In gaining this knowledge, we aim at being able to suggest ways to improve the grocery shopping experience of busy moms; and present insights that can help food retailers in targeting this consumer group in-store. Methodology: We use an iterative approach, and work with photo elicitation interviews. We let our respondents capture their experiences in photographs, which then aid in recalling their memories in follow up interviews. Theoretical perspective: We base our theoretical perspective on environmental psychology where we use the original M-R model, and include personal and situational variables suggested by Bäckström and Johansson (2006); where the latter variable includes the views by Turley and Milliman (2000).

The aim of this essay is to investigate the function and development of non-player characters (NPC) in the TV/computer game Dragon Age: Origins. The NPCs are analysed in order to see if their development is affected by the player character?s (PC) background and interactions. The game?s ethics is also investigated by studying how the NPCs treat the PC and what significance they give to his background and actions.The results show that the NPCs are affected by the PC?s interactions, and furthermore, that they are round characters, which is unusual in TV/computer games.

Protracted social conflicts, as those in Cyprus and Northern Ireland, are based on deep rooted perceptions of identity and definitions of "the other". According to the theory of discursive conflict transformation, war is primarily a social phenomenon, which is legitimated by a discourse of identity defined in terms of exclusionist boundaries and structural ideas of the social relations in society. In order to develop positive peace, the discourse of violence has to be challenged and the discursive structures that enable war have to transform into a counterdiscourse of inclusion and individuality. For the purpose of making a critical peace analysis, I have, with the assistance of established conflict theories, analysed the basic ideas behind the the Annan Plan and the Belfast Agreement and thus been able to interpret to what extent they may foster positive peace. I argue, that in order to provide basic needs on a group basis, power sharing arrangement, based on ethnicity or religion, exacerbates division rather than ameliorating it.

How does a social welfare officer know when a parent with mental illness or behavioral symptoms is harmful to the children? As a social you are confronted with different ethical dilemmas on a daily basis. The social welfare officers have to follow their own authorities, laws, guidelines and regulations while at the same time do everything to satisfy their clients? needs. This inconsistency can sometimes be difficult to handle.

This is a study about employment officers at the Swedish public employment service. The aim of this study was to examine how they understand and use their discretion in their daily work. We used a qualitative method and the data was gathered by semi-structured interviews with eight employment officers working at the same office in a small town in Sweden. Lipskys theory about street-level bureaucracy and Lazarus description of coping theory are applied to analyze the empirical data. The work for the Swedish employment officers have changed over the last years with an increasing focus on control and administration.

My purpose of this study is to investigate whether elementary school is available for students with the disability of autism. If the school is just as accessible for students with autistic syndrome as for students with asperger syndrome, or if the school is marked by equal treatment. I think this is important to highlight since I think it´s a deficiency in the school's accessibility for certain students, and dilemmas occurs regarding students in need of support. In order to provide a validated result according to me, I decided to conduct interviews with a few employees and ask all of them the same questions. The interviews I conducted was performed anonymously.

Thiswork is about the parents ' perception of their children's schooling and schoolsituation. It also addresses the important and fundamental conditions when itcomes to parenting and caring of children, which is an essential andcontributory basis for children's school situation. The work also deals withthe importance of good cooperation between school and home for the children tocome to the school grounds and with the desire to learn and develop. The aim ofthis work is that through a survey get a picture of how parents feel abouttheir child's school situation. But also look at how important interplaybetween school, parents and children to the school situation to be good.

In this essay, I discuss one of the recurring dilemmas for a working recreational pedagogue, namely the hard task of cooperation with parents. As a recreational pedagogue, I am required to work by the curriculum Läroplan för grundskolan, förskoleklassen och fritidshemmet 2011. This policy document talks about what my responsibilities are, including establishing collaboration with parents in terms of the children?s development and education. It happens, however, that the pedagogue and the parent's ethical positions differ.

With the ambitions to rehabilitate individuals with different kinds of work disabilities through work, the government owned Samhall AB has a long history as labour market measure in Sweden.To show Samhall AB its importance, the company has requirements to fulfill the goal that around 5 percent of their employees, at Samhall AB, every year shall be transferred to an employment outside the company, which is called transition. Unfortunately since this goal was introduced it also created several dilemmas. One dilemma is the long lasting female under representation in transitions from Samhall AB to the regular labour market.The essays main task is to investigate the factors behind the female under presentation in transition from Samhall AB through a genus perspective and by using quantitative and qualitative method.The main conclusions are that female under representation in transitions from Samhall AB are basically caused by structural factors. Samhall AB?s strong industrial tradition and particularly the strong segregation between female and males on the regular Swedish labour market may inhibit females in their transitions.

This essay describes how the author gradually gets a deeper understanding for his profession and the development of his professional skills, attitude and practice. The essay contains two main narratives representing examples from the author´s occupational practice, and through those narratives he tells how his practice alters and develops. These stories are also the basis for considering different aspects on how to get good models for practising a profession when you are a beginner, and how to manage ethical dilemmas. The starting point is when the author in the beginning of his career as a rural pastor is visiting a seriously ill parishioner at a province hospital. The course and the outcome of this call is surprising the young pastor, and the author tries to analyze the background to the outcome and assesses several possible explanations for the result of his call. The narrative is used to examine the attitude, the professional skills and the social and existential context for the author at that time. The patriarchal patterns in the parish are illuminated and questioned. In the second part of the essay the author investigates what will happen when pastoral cure transforms to psychotherapy, and how the author deals with phenomena in the therapeutical process such as idealization and secondary traumatization. On basis of texts written by among others Ingela Josefson, Fredrik Svenaeus, Christian Nilsson and Ulla Ekström von Essen the author seeks explanation for the development of his practical knowledge. With references to philosofers as Plato, Aristotle, H.G.