Mast cells have for a long time been known to accumulate around tumors (Maltby et al., 2009). Studies show that they may be important and sometimes essential in tumor angiogenesis, tumor growth and metastasis of tumors (Soucek, et al., 2007; Xiang et al., 2010). In an expression array study (Wensman et al, submitted manuscript) performed on mouse mast cells exposed to tumor conditioned medium, the gene 4-1BB was among the most up-regulated genes compared to control medium. 4-1BB codes for a membrane receptor protein of the tumor necrosis factor superfamily and has been shown to be important in T cell regulation in tumor diseases. This study was performed to investigate if human mast cells up-regulate 4-1BB when they get exposed to tumor conditioned medium.

In this thesis ? concerning didactics of literature ? I perform a reading and theoretical analysis of two pivotal works within reader-response theory, more precisely: Literature as Exploration (1938) and The Reader, the Text, the Poem ? The Transactional Theory of the Literary Work (1978), both written by Louise M. Rosenblatt. The object of this analysis is to examine whether Rosenblatts? theory and methodology can be used to accomplish understanding for ?the other?, what Martha C.

The aim of this Master?s thesis is to examine the librarians? perception of the users of children?s and young people?s literature. Questions posed in this study are: How are the librarians described according to appearance, personality and interaction with the users? How are the librarians described compared to former studies on the subject? Which perception can be seen, based on Douglas Rabers?s theory which describes the role the public libraries can take in the society? The study is based on content analysis. We have examined 15 descriptions of librarians in both picture books and literature for young adults, published between 1985 and 2006.

Feline infectious peritonitis (FIP) is a feline viral disease with high mortality. There is no cure or any effective vaccine available today. Many questions are yet to be answered about this disease and the immune response in affected cats. The aim of the study is to evaluate two different techniques for the study of cytokine profiles in cats vaccinated with a vaccine concept against FIPV. More information about the immune response in these cats could give valuable information to better understand the pathogenesis of the disease and the development of an effective vaccine.

It is popular to keep reptiles as pets in Swedish households. The number of households reporting reptile ownership is more than 15 000 (SCB, 2006). This means that a veterinary practice should consider how to take care of reptiles as patients. The aim of this study was to examine literature and studies concerning safe handling and restraint of reptiles as well as the effects of acute and long term stress response and to suggest a simplified plan for handling reptiles in a veterinary practice. The result of literary studies is that common recommendations for safe handling and restraint of reptiles is based on old techniques and experiences from safe handling of wild animals. The main concern is safety for the veterinary nurse and for the reptile. Stress studies indicate that acute stress response is not harmful for the animal i long term. On the other hand studies of the effect of prolonged stress are not conclusive.

This paper tests the information signalling hypothesis on a sample of firms making open market stock repurchases. Using an earnings-based valuation model, we find that a majority of repurchasing firms are undervalued relative to their economic value. This result is consistent with previous academic studies, which claim that undervaluation is the prevalent factor explaining the observed abnormal return following the announcement of a repurchase program. We do not, however, find any evidence that the repurchase is consciously made by management to provide the market with new information. .

In this study a multiple linear regression was carried out in the interest of analysing a number of variables effect on the final prices of apartments in Stockholm?s inner districts. The result may be employed to predict and observe percentage changes on the final price of apartments in Stockholm in the future. Five models were constructed after which they were analysed and compared. The construction of these models were supported by data from the real estate agency Erik Olsson.

The guest harbor on Utö, Utö Gästhamn, is currently using electricity for heating all of the water used in the showers and taps. Because of the large amount of visitors, especially during the summer months, the hot water usage gets very high and that is also the case for the electrical bills. During the year of 2011 the cost of electricity for Utö Gästhamn reached a total of 257 500 kr. Out of these 257 500 kr approximately 142 000 kr, 55 % of the total cost, were because of the water heating.The report is the result of a cooperation with Skärgårdsstiftelsen, the Green Islands-project and Utö Gästhamn where the mutual goal is to dimension a solar energy system, to promote the sustainable development.Initially the different techniques for the solar energy system are researched. The techniques are plane solar collectors, evacuated tube collectors, pool collectors and photovoltaic cells.

The purpose of this paper is to investigate in which aspects the public library is affected by its local community. This is re-searched by means of an exemplified case study of a Swedish public library in which we analyze governing documents and the library website with respect to environmental scanning and mar-keting of library services.The research questions are: How are the local community?s demands on the public li-brary being described in the governing document? How is the public library?s response to the demands of the local community being described in the operational plan? How are the demands of the local community, as shown in the governing document and the operational plan, re-flected in the marketing of library services on the library website?Our conclusions are that:The demands of the local community are described in a general fashion in the governing document, but there is a lack of concrete political guidelines.The public library's response to the demands of the local commu-nity is described to some length in the operational plan, but not with respect to economical factors.The demands of the local community are reflected to some length in the marketing of library services on the library website. Many of the overall themes that we identify in the governing document and the operational plan can be found in the marketing directed towards important target groups..

Magnesium is an essential mineral that is important for several physiologic and biochemical processes in the body. Deficiency of magnesium is mainly associated with grass tetany, but can also appear in cows during the indoor period. Since long it is known that potassium has a negative effect on the absorption of magnesium. Due to the fact that potassium fertilisation leads to a higher potassium content in forage, it is of interest to study interactions of potassium on the magnesium balance in dairy cows. There are few studies about magnesium feeding to dairy cows in Sweden and the purpose of this study was to investigate how much magnesium and from which feed-sources dairy cows in Sweden get their magnesium. Data was collected from seven farms in the northern part of Uppland and from seven farms in Skaraborg in Sweden.

AbstractThe aim of the studie was to investigate if the Pediatric Early Warning Score system, PEWS, is an useful instrument on a children's inpatient ward, regarding the detecting of deterioration in children's vital signs. For this, a quantitative descriptive design with qualitative elements was used. Method: Study specific questionnaires were distributed to 86 persons (helpnurses, nurses and doctors). Of these, 36 answered and sent back the surveys. Results: Of 36 responses 25 felt experienced a faster detection of deterioration of vital signs in the child.

Inledning: Enligt IAS 19 ska diskonteringsräntan för bestämmande av pensionsskulden bestämmas utifrån räntan på företagsobligationer. Om det saknas en fungerande marknad för företagsobligationer ska räntan på statsobligationer användas. Efter finanskrisen år 2008 ökade räntespreaden mellan dessa två räntor och det uppstod ett problem för länder utan en fungerande marknad för företagsobligationer, däribland Sverige.Syfte: Syftet med denna studie är att undersöka hur svenska börsbolags diskonteringsräntenivå har påverkats av finanskrisen år 2008. Samt vad detta har för konsekvenser på boalgens finansiella rapporter och dess annvändare.Metod: Undersökningen studerar korrelationen som sambandsmått för att mäta hur diskonteringsräntan förhåller sig till soliditeten i svenska börsbolag som redovisar förmånsbestämda pensionsplaner.Referensram: Denna del av undersökningen består av en genomgång av relevanta delar av regelverket (IFRS) samt centrala redovisningsbegrepp och principer.Teori: Teorin består av teoretiska resonemang kring accounting choice, accounting disclosure och earnings management.Resultat & analys: Undersökningens resultat visar att det finns en svag korrelation mellan och diskonteringsränta hos svenska börsbolag med förmånsbestämda pensionsplaner. Dessutom visar resultatet att svenska börsbolag inte längre har en diskonteringsränta i nivå med statsobligationsräntan.Diskussion: Diskussion förs kring hur svenska bolag förhållit sig till regelverket och redovisningsprinciper vid beräkning av sina pensionsskulder samt hur detta har påverkat intressenterna av den finansiella rapporten.Slutsats: Utifrån funna resultat kan slutsats dras att efter finanskrisen har bolag med en låg soliditet valt en högre diskonteringsränta.

[Saknas].

In an effort to evaluate the effects of restorations of float ways on population density of stream dwelling fish in relation to the changes in habitat, I studied the physical habitat restored and channalized sites and their population density of brown trout (Salmo trutta L.) in three streams in the municipality of Sorsele. The differences between the channalized and the restored sites where most noticeable regarding substrate which where generally coarser in the restored sites. The analyses showed that the proportion of habitat that where suitable to the age class 0+ where significantly lower in the restored sites compared to the channalized sites. Regarding age class ?2+, no statistical differences in habitat quality were found.

Uppsatsens syfte är att presentera ett synsätt över hur ledaren kan främja kreativa processer på reklambyråer. För att skapa detta synsätt behöver förståelsen om kreativa processer i en reklambyrå ökas. Studien utgår från att kreativa processer föranleder kreativ reklam. Vi vill understryka att vi både har ett teoretiskt och ett praktiskt syfte.Metoden är en kvalitativ mikroetnografisk studie. Uppsatsens empiriska insamling består av cirka 100 timmar observationer på en reklambyrå följt av fem kvalitativa djupintervjuer på samma byrå.