Background:  Heart failure is a multidimensional phenomenon with high mortality. Heart failure is treated with angiotensin converting enzyme (ACE) - inhibitors or angiotensin receptor blockers (ARBs) that counteract neurohormonal stimuli that occur in heart failure, as well as providing vessel dilatation, which reduces symptoms and the need for hospitalization and increases survival. Despite this, only about 50% of heart failure patients survive 6 years after diagnosis with drug therapy, and as heart failure is increasing globally, due to improved care and treatment and increasing life expectancy of the population, there is a great need for new drugs such as LCZ696 that acts by dual inhibition of the renin - angiotensin - aldosterone system and neprilysin inhibition.Objective: The aim of this literature study was to evaluate the efficacy of current treatment and possible future treatments on mortality and morbidity in heart failure patients.Results: The examined articles show that treatment with ACE inhibitors in patients with symptomatic heart failure reduces the risk of total mortality by 16% over 3.5 years, reduces all-cause mortality or hospitalization due to heart failure with NNT (number needed to treat) = 10.4 over 3.5 years and increases median survival by 9.2 months over 12.1 years in patients with asymptomatic heart failure. Treatments with high-dose ACE inhibitors reduce mortality and hospitalization because of cardiovascular causes and hospitalizations from any cause by NNT = 30 over 3 years. Beta-blockers reduce sudden death and total mortality and cardiac death or non - fatal myocardial infarction with NNT = 38 and NNT = 23, respectively, over 12 months.

Our project is meant to produce a generic medicine for stomach ulcers and heartburns. As Astra Zeneca's patent on Nexium expires in the United states in 2012, our clients wants to take advantage of the market and with using the same active substance as Nexium contains we want to produce a new generic drug, that we named Bluezec..

AbstractTitle: Anabolic Androgenic Steroids ? An analysis of how AAS is portrayed in Swedish media.Author: Jens SundénTutor: Philip LalanderKeywords: AAS, Anabolic steroids, social problems, media, drug abuse, genderThe purpose of this study was to investigate how Anabolic Androgenic Steroids (AAS) are portrayed and described in the media, how AAS is constructed as a social problem, and how society in a social context uses knowledge and power for disciplinary and educational means. The study is based on the perception of AAS as a constructed social problem and analyzes the discourses surrounding AAS depicted in three Swedish newspapers. The sample was prepared on the basis that it represents different aspects of daily Swedish press. The method used in the paper is a discourse analysis with social constructivism and gender as theoretical tools used to analyze the sample material.

Upper secondary schools programme - a qualitative study about the collaboration of the Youth- and family team, the upper secondary schools and the police to prevent drugsAuthor: Åsa GöranssonSupervisor: Björn JohanssonThis essay discuss drug preventative work performed by the members of the ?Upper secondary schools programme?, which is a part of the Youth- and family team of the Social Services. They perform this work in collaboration with the police and upper secondary schools in Örebro.The purpose of this essay is to investigate and describe this collaboration. More specifically, the purpose is to study the contents of documents of the municipality of Örebro concerning drug prevention aimed at youths through collaboration and compare with the actual work that is carried out by the Youth- and family team through collaboration. Further issues dealt with are possible improvements and if the parties concerned feel a need for a documented structure concerning their way of working.I have used a qualitative method and I have interviewed members of parties concerned.

The purpose of this study was to get a client perspective of the different ways to exit from a different role as a drugabuser, and furthermore, how to maintain a drugfree life.The questions of issue were:- What kind of social-psychological conceptions rules the process?- Which motive powers are essential to maintain drug-independence?- Are there any difficulties on the path to social adaptation?Our research was based on interviews with eight persons; five men and three women, from a treatment home in the south of Sweden. The method we used was semi-structured and with a thematic questionnaire. We chose this form due to the fact that we did not want to influence the interviews, as we wanted to know the persons opinions.The result of our study showed that the interviewed persons have some difficulties to adjust in the society and to find new friends especially the interviewed persons with maintenance treatment. Marginal problems as, for example, the lack of not having a work or a home can complicate a further development for the group with maintenance treatment.

AbstractBackground. The need for drugs delegation is increasing as more and more sick people are cared for at home and too few nurses working in home health care. Because of this, the number of delegations per nurse is often unacceptably high.Aim. The aim of this study was to describe the public health nurses´ experience in drugs delegation to home care staff in home care.Method. In this study a qualitative method with an inductive approach was used.

Karlsson. A (2015). Importance of spirituality and social support for quitting narcotics - Experiences of the12 step program. Bachelor thesis in Public Health science. Department of work- and public health science.

Aim: The aim of this study was to examine whether addicted in society maintain their personal dignity. Many studies about this issue have beenfocused on how hard it is to be an addicted, but few have focused on how an addicted handle this situation. Our preconception before this study was that addicts are a stigmatized group not treated with dignity. With this as starting point, our aim has been to let the addicted with their own words describe how they handle their situation and witch strategies they use to uphold their dignity.Method: A qualitative approach is used; we have condicted five semi structured in- depth interviews. The information we have obtained through interviews, we have in the analysis weighed against the theories we believe are relevant to our preconception.We have then categorized the collected information after those themes we found central in the interviews and which we have found can be related to the main questions of this study.Result: The results show many strategies about how people with drug- and alcohol abuse handle their situation.

This study examines the connection between Sweden`s crime rate and financial aid, focusing on the effects of social spending on different types of criminal activity in the Swedish municipalities between 2000 and 2022. Using theories such as social support theory and utility maximization, the study investigates the relationship between economic assistance and crimes like theft, attempted murder, drug offenses, and assault. The results suggest a complicated relationship: financial aid is associated with a rise in drug offenses and assaults but a decrease in larceny and robberies, when controlling for all observed and unobserved time invariant factors in the municipal factors (a fixed effects panel data model). However, when we test our model for robustness, the effects disappear meaning that other factors that are time varying in the municipality are biasing our estimates. Examples for this may be factors like peer pressure, substance addiction, and socioeconomic conditions that have a considerable impact on criminal conduct, financial aid alone may not be adequate to curb crime.

Karlsson. A (2015). Importance of spirituality and social support for quitting narcotics - Experiences of the12 step program. Bachelor thesis in Public Health science. Department of work- and public health science.

Karlsson. A (2015). Importance of spirituality and social support for quitting narcotics - Experiences of the12 step program. Bachelor thesis in Public Health science. Department of work- and public health science.

The purpose of this study was to investigate the kind of treatment strategies used by Swedish Veterinarians with cattle practice when treating calves with symptoms of pneumonia. A questionnaire, consisting of seven questions, was sent to one hundred veterinarians who have had practice with cattle and are employed by the Swedish Board of Agriculture. The survey was answered by a total of 73% of the Veterinarians. Of the respondents, 73 % use Penicillins as their first choice of drug for treating calves with symptoms of pneumonia, and as their second choice 64 % use Tetracycline. Supplementary treatment such as NSAID (non-steroidal anti-inflammatory drugs) and/or SAID (steroid anti-inflammatory drugs) are used by 97.5 % of the respondents.

Karlsson. A (2015). Importance of spirituality and social support for quitting narcotics - Experiences of the12 step program. Bachelor thesis in Public Health science. Department of work- and public health science.

AbstractTitel: Hjälpen till ett drogfritt liv- En kvalitativ studie om återfall och återfallsprevention.Writers: Jonna Håkansson och Louise Hag.Keywords: Abuse, addiction, relapse, relapse prevention.   Abuse is a major problem and leads to negative consequences for the individual, such as illness, criminality and death. It?s also a big problem in the society, because the most common crimes are drug-related and the consequences lead to high economic costs. In order to overcome an addiction, treatment is often required.

Itraconazole is a third generation azol, a fungicide which acts by inhibiting ergerosterol synthesis in the fungal cell membrane, and thereby disturbing fungal regeneration. It has proven to be less toxic, to have a broader spectrum of activity and to be more potent than its predecessor ketoconazole. Itraconazole is only available in therapheutics approved for human use. Pharmacokinetic studies has been performed in humans, dogs, cats and laboratory animals. Although itraconazole has been used tentatively with good effect against fungal infections in horses, no pharmacokinetic studies have yet been done.