Platelets are important for the healing of damaged blood vessels since they have an importantpart to play in the coagulation process. At the same time, the blood must be kept fluid and notcoagulate at the wrong time. Therefore there are factors that effect the aggregation of plateletsin a positive or a negative way.Previous investigations have shown that platelets during stirring conditions produce reactiveoxygen species (ROS) that weaken the inhibiting effect of nitric oxides (NO) on platelets andthat the drug Dexamethasone (Dex) can reduce the ROS-production.The aim of this project was to investigate if glucocorticoids, in this case Dexamethasone,could restore the inhibiting effect of NO on platelets and if there was any decrease in ROS-production.The result of the ROS-measurements showed a great variance and it was difficult to draw anyconclusions from them, but a clear decrease in ROS, as previous reported, was not shown. In the aggregation experiments the inhibiting effect of NO was observed through the drug S-nitroso-N-acetylpenicillamine (SNAP), a NO-donator.From the aggregation experiments, the result seemed to be that SNAP during longerincubation time lost its inhibiting effect, probably because the cells become desensitized.With superoxid dismutase (SOD), the effect of SNAP increased, both in the experiment withlonger and shorter incubation times. Dex seemed to reinforce the aggregation in relation toboth SOD and SNAP.

The purpose of this essay was to examine what consequenses of alcohol and narcotics that youth magazines describe and how the user and addict is described. My porpose was also to examine what situations the magazines claim that alcohol and narcotics are related to.The questions for my studie was:1. How is an alcoholic/drug addict /user described in youth magazines?2. What situations are related to alcohol/narcotics in youth magazines?3.

The aim of this study is to investigate social workers? attitudes toward alcohol abuse, regarding the relationship between the individuals? own responsibility of causing and solving its addiction. The thesis also aims to gain a deeper understanding of what the respondents perceive as important in the creation of these attitudes. In this qualitative study six social workers who all have experiences of working with clients suffering from alcohol abuse are interviewed. The results from the interviews are analyzed with social constructivism as theoretical framework, as well as theories regarding how attitudes are created.

Our study aims to investigate whether resilient children share common factors that could explain them not following the expected course of development for said group. The study also sets out to explore which strategies resilient children implement in order to cope with their situation.The study is based on the following questions:How do resilient children describe their experiences from growing up with parents with substance abuse problems? What risk and protective factors do they mention in their biographies?We use the system theory and Goffman's dramaturgic perspective as analytical tools.  The system theory could help us see the family as a system, while Goffman's theory might help us understand how resilient children find different strategies, and why they implement these strategies, to hide their family problems.The results show that the most important factors with a positive effect on resilient children were: to have somebody else important in their lives, to have goals in life, to have a safe haven, to think independently and to develop a high level of independence early in life..

There is little knowledge about abuse of anabolic androgenic steroids (AAS) in Sweden. Thispaper aims to explore, from a discourse psychological angle, how persons with experience ofanabolic androgenic steroids (AAS) construct there identities.The theory and method used as a frame for the paper is discursive psychology, depending on thefocus in the paper of human beings use of language in the construction of identities. Forcollection of data interviews were made. The six respondents al had experience of use of AAS.The interviews illustrated how users of AAS speak about AAS, and create there identity, inrelation to AAS. In the interpretation of data we used two different tools, used by discursivepsychologists, interpretative repertoires and subject positions.

Background:  Heart failure is a multidimensional phenomenon with high mortality. Heart failure is treated with angiotensin converting enzyme (ACE) - inhibitors or angiotensin receptor blockers (ARBs) that counteract neurohormonal stimuli that occur in heart failure, as well as providing vessel dilatation, which reduces symptoms and the need for hospitalization and increases survival. Despite this, only about 50% of heart failure patients survive 6 years after diagnosis with drug therapy, and as heart failure is increasing globally, due to improved care and treatment and increasing life expectancy of the population, there is a great need for new drugs such as LCZ696 that acts by dual inhibition of the renin - angiotensin - aldosterone system and neprilysin inhibition.Objective: The aim of this literature study was to evaluate the efficacy of current treatment and possible future treatments on mortality and morbidity in heart failure patients.Results: The examined articles show that treatment with ACE inhibitors in patients with symptomatic heart failure reduces the risk of total mortality by 16% over 3.5 years, reduces all-cause mortality or hospitalization due to heart failure with NNT (number needed to treat) = 10.4 over 3.5 years and increases median survival by 9.2 months over 12.1 years in patients with asymptomatic heart failure. Treatments with high-dose ACE inhibitors reduce mortality and hospitalization because of cardiovascular causes and hospitalizations from any cause by NNT = 30 over 3 years. Beta-blockers reduce sudden death and total mortality and cardiac death or non - fatal myocardial infarction with NNT = 38 and NNT = 23, respectively, over 12 months.

The purpose of this study is to examine how young people with experience of running away and/or getting thrown out look upon and understand the phenomenon. Another purpose of thestudy is to examine how the youth evaluate the help and support they did or did not receive at the time of their experience, as well as to examine what the ultimate help and support would be according to them. The study was done in a qualitative approach with the use of focus groups and individual interviews. The results were analyzed through the perspective of the ?sociology of childhood?.

The main objective of this study was to investigate the possible design of a horticultural therapy program in Swedish correctional treatment facilities. In the USA the use of horticultural therapy in offender rehabilitation is much more frequent compared with Sweden. The aim of these programs typically contains education for inmates. Research has been made indicating that these programs can have positive effects on psychosocial behavior and on vulnerability to substance abuse among incarcerated offenders. In this study the examples of these programs was categorized and analyzed from three perspectives; Vocational, social and therapeutic horticultural programs.

Bakgrund: Under år 2012 ökade anmälningarna av barnmisshandel. Barnmisshandel oavsett art innebär alltid en kränkning för barnet och om det dessutom sker av en anhörig har barnet förlorat den person som ska stå för den fasta tryggheten. Både fysisk misshandel, psykisk misshandel eller omsorgsvikt skadar barnet allvarligt och innebär stora hälsoproblem för barnet. Därför var det av stor vikt att identifiera barnet i ett tidigt skede för att kunna ge stöd och agera utefter behov. Syfte: Syftet med studien var att belysa distriktssköterskans erfarenhet av att se och identifiera kännetecken på ett misshandlat barn.

The aim of this essay was to describe how school social workers can help and support students with parents who abuse alcohol or other drugs. We wanted to see how school social workers room for action is presented and how it affects their work with students living with parents who are abusing. We used a qualitative method to elucidate how school social workers handle this issue in a more profound way. By conducting semistructured interviews with six school social workers in one province in southern Sweden we gained exhaustive and detailed answers. In the analysis we used street level bureaucracy and theory of recognition.

Our project is meant to produce a generic medicine for stomach ulcers and heartburns. As Astra Zeneca's patent on Nexium expires in the United states in 2012, our clients wants to take advantage of the market and with using the same active substance as Nexium contains we want to produce a new generic drug, that we named Bluezec..

Folkhälsovetenskapligt program.

Syftet med studien var att belysa faktorer som påverkar omvårdnaden av patienter med ett intravenöst drogmissbruk (IDU). Bakgrund: Sjuksköterskor har ofta bristande kunskap om droger och om hur man ska hantera den kliniska omvårdnaden av patienter som missbrukar droger. Bristande kunskap om drogmissbruk bland vårdpersonalen skapar rädsla vilket i sin tur kan leda till att IDU får ett sämre mottagande. Det förekommer även fördomar om denna patientgruppen bland personalen. Metod: studien genomfördes som en allmän litteraturstudie baserad på åtta vetenskapliga artiklar inom tidsintervallet 2003-2009, sökta i databaserna PubMed, PsyhInfo, ELIN@lund samt Cinahl.

The objective of this paper is to describe and analyze female irregular immigrants and their experience of how relationships with other people affect their lives and identity.A qualitative method is used in the study, because my main purpose is to analyse the respondents? lives and life experiences. The analysis is based on a symbolic interactionism perspective. The results are also analyzed based on previous research and the concepts underlying the paper; irregular immigrants, discrimination, power and identity.In summary, the respondents have a clear picture of how they live and experience their relationship to others and themselves and how this affects their lives and identity.Their experiences affect their lives and influence their behaviour and identity when they interact with others. Their own view of their situation means that they are afraid to seek care or report sexual abuse, threats or other similar conditions.

The essays main intent is to examine whether there has been a proper implementation of the Council?s directive 1999/70/EG into Swedish law regarding the requirement for measures to prevent the abuse of successive fixed-term employment contracts. To achieve this purpose there is a need for an examination of current law. The essay also has some secondary purposes. One of these secondary purposes is the question of whether the implementation of the Council?s directive 1999/70/EG has lead to a reduction of the workers employment protection, which is closely connected to my main question and the violation case.