Rheumatoid arthritis is an autoimmune disease, where joints are attacked by the own immune system, leading to chronic inflammation and destruction of bone and cartilage. Inflammation is a complex process, controlled by many different substances. One of them is adenosine, which has anti-inflammatory properties. In this project, three polymorphisms in different genes, involved in synthesis and signaling of adenosine, were genotyped for 188 patients with RA and 362 controls without RA. The results shows that for the polymorphism in A2a, a gene coding for an adenosine receptor, there was no significant difference in genotype distribution between the groups.

Denna rapport är en fallstudie som återspeglar framtagandet av en webbplats åt det norska Diabetesforbundet. Webbplatsen är ett community där personer skapar användarkonton och interagerar med varandra med hjälp av ett antal funktioner som finns att tillgå. Då själva utvecklingen av webbplatsen har varit huvudmålet med examensarbetet fokuserar denna rapport på att förklara den praktiska implementeringen. De tekniker och metoder som använts i det praktiska arbetet såsom kontextuellt utforskande och användbarhet definieras och förklaras för att sedan användas vid argumentation kring designval för webbplatsen. Den utvecklingsmetod som använts i det praktiska arbetet har varit en Agile Software Development-metod som kallas Extreme Programming.

Erythropoiesis is a complex and carefully controlled process which is mainly regulated by erythropoietin. Using flow cytometry cells in a blood sample can be analyzed one by one. ADVIA 2120 using flow cytometry for analysis of red blood cells (RBC) and reticulocytes. Red blood cell distribution width (RDW) is a component of the RBC method. RDW indicates size variation on erythrocytes and is measured as a percentage of the mean cell volume (MCV). By measuring the RDW anemia can be divided into makrocytic, microcytic or normocytic. Reticulocytes refract light more strongly than red blood cells because they contain some cellular debris. The number of reticulocytes in the peripheral blood reflects erythropoiesis in the bone marrow. The purpose of this project was that by approved methods to establish reference ranges for the parameters, RDW and reticulocyte counts.The individuals who participated in the study, n=124, were considered healthy and had varying ethnicity. Reference subjects had not donated blood the last six months and participation in the study was voluntary.The statistic evaluation includes examination of distribution, and reference ranges for both men and women were established using the 2.5:t and 97.5:t percentiles. The calculated reference interval for RDW was between 12.0 ? 14.3% and the calculated reference interval for reticulocytes was between 38.0 ? 112.8 x109 cells/L. The results showed a significant difference between males and females for the parameter reticulocytes was seen. The difference indicates that different reference ranges should be established for men and women (p<0,0001). No significant difference between males and females were seen for RDW (p=0,74) indicating that the same reference ranges can be used for both men and women. .

The music distribution in Sweden and the world is rapidly changing. The music industry, however, has been reluctant to change the way they distribute music. The consequence has been that illegal music files have been available for downloading to anyone with an Internet connection. Because of the illegal downloading a new law have been implemented in an attempt to stop this behaviour. Our theory is that in implementing the IPRED-law, the sites that were hosting most of the illegal material will experience a severe decrease in traffic.

 AbstractThis Master?s thesis analyses the dynamics of the medieval counterweight lever engine, ortrebuchet, a type of mechanical artillery. The purpose is to study the differences between different types of these machines, and see if computer simulations can be used to validate preserved advice on construction. Simulations include machines with a fixed counterweight, a hinged counterweight and a combination of both counterweights.Due to the almost complete lack of archaeological finds and insufficient historical source material there are still, after more than a century of research, many unanswered questions concerning the design and performance of these machines.The present study is based on an analysis by Jahsman (2004). A more detailed mathematical model employing Coulomb-friction is used.

The role of small businesses is fundamentally important for the economic development in countries. Within this context, business incubation is used as an entrepreneurship development instrument to promote and support new firms in the early stage of their existence. However, research in the field tends to disregard the perspectives of incubatee entrepreneurs. The performed investigation is based on interviews with entrepreneurs from two different business incubators at Swedish universities. This study uses a Situated Learning Theory (SLT) as a theoretical framework, to examine the entrepreneur's experience of the learning environment in a business incubator.

AbstractThe purpose of this minor thesis is to describe and systematize the Swedish debate about Sweden?s participation in the defence community of the European Union. Should Sweden take part of this or not? My aim is to describe the debate in a structured and legible way, so that the reader can get a comprehensive picture. The questions of the study are:· Which actors join in the Swedish debate about Sweden?s military participation in the EU:s defensive community; the possible common defence of the EU and the EU:s military crisis management?· Which arguments are delivered (for and against) in the debate?To be able to fulfil the aim of this study I have done an argumentation analysis.

The aim of this essey was to find out what kind of help problem gamblers can get at social service offices in the region Västra Götaland in Sweden. We also examined the knowledge regarding gambling problems at social sevice offices and who the head of the social service offices regarded having the responsibility for the question of helping problem gamblers. As a last question we wanted to know if the size of the population in the community had an impact on these questions. Central questions in our essey asked are:How much help does the social service offices in the region Väsra Götaland offer problem gamblers? Who has the responsabilety to help problem gamblers according to social service offices?What knowledge does the social service offices have concerning problem gambling?Does the population of the community have an impact on theese questions?This is a quantitative study made as a webbservey to the head of the social service offices in the region Västra Götaland.

The purpose of this study is to explore the factors affecting an individual's working life mobility and how this mobility is perceived by the individual. The study has a qualitative approach and the theoretical part is based on Castells', Giddens' and Bauman's theories of modern society and employment in relation to the individual. The study concludes that external circumstances in combination with internal driving forces are the reasons behind changing careers. The process is predominantly perceived as positive, especially education tends to strengthen self-identity. Work in general is regarded as important for a person's identity and new career changes are expected in the future..

I denna studie studeras den europeiska integrationen ur ett konvergensperspektiv där inkomstkonvergensen spanska regioner emellan får fungera som exempel. Med hjälp av ett paneldataset innehållande data på bland annat inkomst och tilldelade fondmedel från EU för 17 spanska regioner för perioden 1980-2004, gör vi konvergensskattningar med fixed effects och finner stöd för inkomstkonvergens på 2,7 procent. Denna inkomstkonvergens innebär att regioner med initialt låg inkomst i genomsnitt har haft en högre tillväxt än rikare regioner. Vi kan dock ej finna något starkt samband mellan de strukturfonder regionerna erhållit och denna konvergens..

The assignment is issued by Scania Maintence AB seeking a new approach to detect power changes in their industrial processes. The work has taken place at Ångströmslaboratoriet and tests have been performed at Scania AB Södertälje.Today?s society consumes enormous amount of energy. In both economically and environmental view, it is important that the processes are effective, with high power factor. There are many ways to measure power in the industry, what they all have in common is that the installation is advanced, requires time and planning.

Background: Basic hygiene is an important measure to prevent healthcare associated infections, save patients? lives, and reduce economic costs for health care. Healthcare associated infections are a threat to patient safety. In community care persons who are the care takers are a risk group and nurses must make sure that basic hygiene procedures are followed.Method: Literature studies with descriptive design, article search in databases Cinahl and PubMed. The results found are based on twelve chosen articles.Aim: To describe factors related to adherence to basic hygiene and how nurses in community care can help to improve compliance with these procedures.Results: In the nursing staff and leadership in health care interest in and the understanding of basic hygiene is described as being of most importance.

BackgroundThis paper is based on an issue raised by the organization Energigas Sverige, which together with the Ministry of Finance has posed the question about the fiscal impact of an increase in biogas production. Since the fiscal effects of an increased biogas production are both positive and negative, due to reduced use of fossil fuels, we want to investigate this further.PurposeThe purpose is to describe and explain the obtained fiscal impacts of an increased biogas production and based on our problem: ?What are the obtained fiscal effects caused by an increase in biogas production?? we could see the following fiscal effects: positive impact on employment, increased revenues of social security contributions and income taxes, reduced unemployment costs and reduced tax revenues on fossil fuels. These effects are summarized in a negative tax revenue of 2,6 billion SEK. Along the summarized negative effect we also accepted one of the two prepared hypotheses, which stated that an increase in biogas production leads to a negative fiscal impact. Design/Methodology/ApproachWe have chosen to work from an Anglo-Saxon scientific tradition and furthermore, we have a positivistic approach when we want to explain the relationship between cause and effect of an increase in biogas production and the following fiscal impacts.

Sammanfattningen syftar till att ge en övergripande bild om vad arbetet handlar om, för att skapa en nyfikenhet till att läsa hela arbetet.Studiens syfte var att analysera alternativa distributionssystem för petroleumprodukter från Gävle Hamn. Där vi har valt två slutdestinationer, norra Stockholmsregionen med Brista som ett alternativ och det andra alternativet är Västerås. De faktorer som vi har utgått från när vi har analyserat distributionssystemen är ekonomiska, miljömässiga och tekniska möjligheter.Den metod som användes var kvalitativ och det empiriska materialet inhämtades genom intervjuer. I studien har nio respondenter intervjuats, vi anser att de personerna har varit relevanta för studiens syfte. Resultatet har analyserats med hjälp av tidigare forskning och teorier inom ämnet.Resultatet visade att det skulle vara ekonomsikt, miljömässigt och tekniskt möjligt att starta upp petroleumtransporter till norra stockholmsområdet.

In Sweden has the temporary agency work industry settled in an explosive way since the deregulation of the unemployment agency monopole in 1993. The demand of civil right for the employer that is rented out confronts the entire labour law regulation with new challenges.The purpose with this paper is an investigation of the principle of equal treatment in The Swedish temporary agency work act and also to create a deeper understanding of the effects of labour and employment relationship. An investigation of relevant collective agreements will be done to highlight the difficulties the principal of equal treatment is exposed to. Further on is there a will to gain understanding for the wage concept and what possible can be included in the wage concept in relation to the principal of equal treatment in The temporary agency work directive. By using the dogmatic method, an approach to descriptive identifying relevant sources of law and clarify the legal situation in the area.In the conclusions it will be determined that the principle of equal treatment in The Swedish temporary agency work act have different effects depending on if the temporary agency or if the client corporation is tied to an collective agreement alternative if a collective agreement is completely missing.