Our study aims at investigating the unit manager?s, within LSS, perceiveddiscretion, when people with Down´s syndrome develop Alzheimer?s disease. We wanted to know what they perceive as limiting factors or facilitators in order to meet changing and/or emerging needs, as well as how they interpret their discretion in relation to this. We have conducted semi-structured qualitative interviews with five unit mangers within LSS.When analyzing the interview material, we have used a theoretical approach from a street-level bureaucracy and from the unit managers? perceiveddiscretion point of view.Our study?s result demonstrate that the unit managers are experiencing a wide discretion and do not feel a need to widen their identifieddiscretion..

Amyotrophic lateral sclerosis is one of the major neurodegenerative diseases, causing an ascending paralysis that usually kills the patient within a few years from disease onset. The motor neurons show aggregates of proteins which in approximately 20 % of cases of the familial form contain mutated SOD1 protein. Trehalose is a disaccharide which has been shown to reduce protein aggregation and increase viability in cell models and alleviate symptoms in animal models of several neurodegenerative diseases associated with protein aggregation. When given orally to the SOD1G93A mouse model of ALS, trehalose failed to slow down the disease progression, which has led to questions about the uptake and distribution of the molecule in this mouse strain. The aim of this study was to investigate whether significant levels of trehalose reach the central nervous system of the SOD1G93A mouse after oral administration. This was performed by a trehalose assay of the brain of trehalose treated animals. A glucose assay was optimised for use in small samples of brain lysate after the digestion of trehalose into glucose by trehalase, and the difference in glucose concentration before and after digestion represented the trehalose level.

Trycksår är ett utbrett problem inom vården och innebär ökat lidande för patienter, en ökad belastning för vårdpersonal och en merkostnad för samhället. Syftet med den här litteraturstudien är att undersöka vetenskaplig litteratur för att finna de metoder som har god effekt avseende att minska risken för uppkomst av trycksår. Metoden är en litteraturstudie baserad på elva vetenskapliga artiklar. För att uppnå evidens har en modell enligt Goodman i sju steg använts som inspiration. Resultatet visar att användande av viskoelastiska madrasser i kombination med vändning av patient var fjärde timma ger ett bra skydd men även kännedom om riktlinjer och hur dessa implementeras är avgörande för hur preventionsarbetet får genomslag på varje enskild avdelning..

Bakgrund: Crohns sjukdom och ulcerös kolit är två huvudtyper som utmärker inflammatorisk tarmsjukdom. Inflammatorisk tarmsjukdom påverkar mag- och tarmkanalen och har ett oförutsägbart sjukdomsförlopp. Inflammatorisk tarmsjukdom debuterar vanligtvis i åldern 15-30 och kan ge ogynnsamma konsekvenser i personens dagliga aktiviteter eftersom han eller hon är upptagen med att exempelvis studera, skapa karriär eller bilda familj. Sjukdomarna har flera gemensamma särdrag där de förekommer i så kallade skov med perioder med försämring då tarmslemhinnan blir inflammerad och sårig, vilket leder till symtom som exempelvis blodiga eller slemmiga diarréer, viktnedgång, buksmärtor och trötthetSyfte: Syftet med uppsatsen är att beskriva konsekvenser av att leva med Crohns sjukdom eller Ulcerös kolit hos vuxna personer.Metod: En litteraturöversikt. En litteratursökning gjordes som ledde till sex granskade artiklar.

Bakgrund: Truppgymnastik är en relativt ung tävlingsgren inom gymnastik med ursprung från de Nordiska länderna. I Sverige är det den mest utövade formen av tävlingsgymnastik med flest rapporterade  skador i nedre extremiteten samt återkommande besvär i ryggen. Tester i syfte att förebygga skador är efterfrågade och få studier har utvärderat tester för idrottande barn och ungdomar.Syftet med studien var att beskriva en grupp unga truppgymnaster utifrån bakgrundsvariabler, och rörelsekontroll med screeningtestet Performance Base Matrix samt att mäta förekomst av muskuloskelettala skador under en period på sju månader. Metod: Nitton unga truppgymnaster (flickor,7-9 år) genomförde screeningtestet Base Matrix i syfte att bedöma deras rörelsekontroll vid låg respektive/ low threshold och hög belastning/ high threshold. Testerna analyserades visuellt och genom videoupptagning. Resultatet av testerna dokumenterades i ett protokoll som bearbetades on-line samt för beräkning av procentuell förekomst av sämre utförd test i form av svaga länkar.

I denna uppsats försöker jag förklara vad ungdomsbrottslighet innebär, vilka faktorer gör så att man som ungdom utför brottsliga handlingar och hamnar i kriminella gäng samt hur man på bästa sätt kan förebygga ungdomsbrottslighet. Jag har gjort en litteraturöversikt och sedan behandlat informationen med hjälp av två tidigare teorier, sociala bandteorin och inlärningsteorin. För att få mina frågeställningar besvarade har jag fokuserat på ungdomar och hur det kommer sig att de väljer en kriminell väg. I diskussion och resultat stycket presenterar jag vad jag kommit fram till i analysdelen och analyserar resultatet med dem valde teorierna. I uppsatsen tar jag även upp om det finns någon koppling mellan maskulinitet och brottslighet och iså fall vilken..

Working as a veterinary nurse includes advising animal owners, helping them to make discisions through well-based facts and experience. Preemptive spaying of the healthy bitch brings many advantages and disadvantages. It leads to cessation of gonadal hormone production, and how the exact extent the surgery affects the dog is not yet fully understood. The sex hormones mainly control the reproductive system, but receptors of these hormones are found in many tissues of the body, and have complex relationships with other hormone systems. Spaying decreases the metabolism although the bitch gets an increased appetite, which enhance the risk of obesity, unless the owner restricts food intake.

Staphylococcus aureus is the most clinically important Staphylococcus species and is associated with high mortality in patients with positive blood cultures. S. aureus bacteria may cause a variety of disease manifestations ranging from minor skin infections to life-threatening conditions such as pneumonia, meningitis, osteomyelitis, endocarditis, toxic shock syndrome (TSS) and sepsis. This microorganism belonging to the gram positive cocci may also be part of the normal flora. In Sweden, penicillinase-stable penicillins are the primary alternatives to treat S.

ECG-Screening for young elite athletesAbstractBackgroundSudden cardiac death (SCD) during physical activity is a frightening and emotional tragedy that draws huge media attentions when it occurs. Fortunately it is a relatively uncommon occurrence but happens nonetheless to young athletes who often seems to be in perfect health. SCD is used as a term for sudden unexpected complications on the cardiovascular system that leads to a deadly outcome normally within the first hour of onset of symptoms and the cause is some sort of underlying cardiovascular disease that gets triggered by physical activity.Normally athletes gets divided into two groups dependent on age, over and under 35 years, and this studies focus is on the younger group since it is often during this period athletes are at the elite level. It is also in this category the most unexpected sudden deaths occur that is not due to coronary atherosclerosis, which is the dominant cause of death, and drastically increases, for people over 35 years old.AimThe aim of this study was to scientific and unbiased analyze peer-reviewed clinical articles todescribe the pros, cons and cost to implement an ECG-screening as a standard before physicalactivities for specifically defined elite athletes.MethodA systematic review was performed and after all data collection 21 articles was chosen to beused as a base for both background and analyze. At the end 10 articles was fulfilling the criteria to be used at the analyze and later the results.ResultsThe implementation of ECG-screening has reduced SCD in Italy by 89 % between the years 1979-2004.

ECG-Screening for young elite athletesAbstractBackgroundSudden cardiac death (SCD) during physical activity is a frightening and emotional tragedy that draws huge media attentions when it occurs. Fortunately it is a relatively uncommon occurrence but happens nonetheless to young athletes who often seems to be in perfect health. SCD is used as a term for sudden unexpected complications on the cardiovascular system that leads to a deadly outcome normally within the first hour of onset of symptoms and the cause is some sort of underlying cardiovascular disease that gets triggered by physical activity.Normally athletes gets divided into two groups dependent on age, over and under 35 years, and this studies focus is on the younger group since it is often during this period athletes are at the elite level. It is also in this category the most unexpected sudden deaths occur that is not due to coronary atherosclerosis, which is the dominant cause of death, and drastically increases, for people over 35 years old.AimThe aim of this study was to scientific and unbiased analyze peer-reviewed clinical articles todescribe the pros, cons and cost to implement an ECG-screening as a standard before physicalactivities for specifically defined elite athletes.MethodA systematic review was performed and after all data collection 21 articles was chosen to beused as a base for both background and analyze. At the end 10 articles was fulfilling the criteria to be used at the analyze and later the results.ResultsThe implementation of ECG-screening has reduced SCD in Italy by 89 % between the years 1979-2004.

Bakgrund: Osteoporos har under de senaste decennierna utvecklats till en av de stora folksjukdomarna. I Sverige drabbas cirka 70 000 människor av osteoporosrelaterade frakturer varje år och av dessa är det främst kvinnor som drabbas. Risken för att en svensk kvinna någon gång under sin livstid skall drabbas av en osteoporosrelaterad fraktur är 50 %. Hur snabbt en kvinna förlorar benmassan samt hur stor benmassa hon har från början är avgörande för om hon kommer att drabbas av osteoporos och därför är prevention i ett tidigt skede viktigt. Syfte: Syftet med litteraturstudien var att belysa preventiva åtgärder för premenopausala kvinnor som kan förebygga primär osteoporos.

Causes of thrombocytopenia in dogs ? a retrospective study of 123 cases The purpose of this retrospective case study was to determine which diseases are associated with thrombocytopenia in Swedish dogs. Records of 123 dogs with thrombocytopenia were evaluated. The most common cause was neoplasia-associated thrombocytopenia (32%). The largest proportion within this group was unspecified neoplasia.

The aim of this report is to improve the fire safety at Hallsta Paper Mill in Hallstavik, Sweden. In order to do so large parts of a fire-protection management system for the paper mill has been created. The report begins with giving a general description of management structures and fire-protection management systems. An account is given for how management structures are designed, and how they should be implemented, maintained and updated. Thereafter follows a description of what routines and instructions should be included in a fire-protection management system..

This student report is about canine atopic dermatitis It includes a description of the immunologic mechanisms and how the reaction affects the body. The symptoms are various, most common is pruritus, erythema and alopecia and directly associated with the immunologic reaction. The diagnostic process includes symptoms, physical findings, differential diagnosis, intradermal test and serological test. The options of treatment are several and vary for each patient. The report includes hyposensitization, medical treatment such as corticosteroids, antihistamin and cyclosporine, topical treatment, fatty acid supplements and environmental treatment. The prognosis is individual for each patient due to their different response to the treatment. It may take a while to find the right combination of treatments to achieve satisfactory control of the disease..

ECG-Screening for young elite athletesAbstractBackgroundSudden cardiac death (SCD) during physical activity is a frightening and emotional tragedy that draws huge media attentions when it occurs. Fortunately it is a relatively uncommon occurrence but happens nonetheless to young athletes who often seems to be in perfect health. SCD is used as a term for sudden unexpected complications on the cardiovascular system that leads to a deadly outcome normally within the first hour of onset of symptoms and the cause is some sort of underlying cardiovascular disease that gets triggered by physical activity.Normally athletes gets divided into two groups dependent on age, over and under 35 years, and this studies focus is on the younger group since it is often during this period athletes are at the elite level. It is also in this category the most unexpected sudden deaths occur that is not due to coronary atherosclerosis, which is the dominant cause of death, and drastically increases, for people over 35 years old.AimThe aim of this study was to scientific and unbiased analyze peer-reviewed clinical articles todescribe the pros, cons and cost to implement an ECG-screening as a standard before physicalactivities for specifically defined elite athletes.MethodA systematic review was performed and after all data collection 21 articles was chosen to beused as a base for both background and analyze. At the end 10 articles was fulfilling the criteria to be used at the analyze and later the results.ResultsThe implementation of ECG-screening has reduced SCD in Italy by 89 % between the years 1979-2004.