This study was performed in order to investigate the difficulty in diagnosing retrobulbar disease with ultrasound. A retrospective study was accomplished to investigate the use of ultrasound in patients with suspected retrobulbar problems, and how often the examination is diagnostic. The computer based patient files, at the University of Agricultural Science in Uppsala, were searched for dogs with suspected retrobulbar disease. During 1999-01-01-2004-04-14, 14 patients fulfilling the search criteria were found. The patient records were studied, and the written reports from the ultrasound examinations were compared with the printed pictures from the examinations.

SAMMANFATTNINGSjukhusinfektioner förlänger vårdtiden och fördyrar vården samt innebär ett ökat lidande för patienten. Urinvägsinfektion (UVI) är den vanligaste vårdrelaterade infektionen. Behandling med kateter à démeur (KAD) är omfattande inom akutsjukvården. KAD anses vara den främsta orsaken till vårdrelaterad UVI.Syftet med litteraturstudien var att beskriva faktorer i sjuksköterskans arbete som påverkar incidensen för utvecklandet av kateterassocierad UVI.Underlaget för resultatet utgörs av 24 vetenskapliga artiklar som på manuell och systematisk väg söktes i databaser. Analysen av artiklarna resulterade i sju ämnesområden som utgör delarna i resultatet.

The aim for the project was to develop a risk analyse tool for measuring the fire safety level in Cultural Heritage buildings of Visby, Gotland. In 1995 Visby were taken into the Unesco:s World Heritage List with the explanation ?Visby is an outstanding example of a Northern European walled Hanseatic town which has in a unique way preserved its townscape and its extremely valuable buildings? One of the demands for the tool was that it should be easy to use and result into a ranking level in examined buildings. The user of the tool is recommended to be personnel in the fire department. To develop the tool a Multi Attribute Decision Making (MADM) method was used.

White-Nose Syndrome, WNS, is an emerging fungal disease in the Northern American bat population causing mass mortality in infected hibernacula. Geomyces destructans is a newly discovered psychrophilic fungus causing WNS but the pathogenesis and epidemiology of the disease is not yet fully clarified. Geomyces destructans has been found in Europe but has not been a cause of mass mortality there. This study is the first investigation done to see if G. destructans is present in Sweden.

Sahlgrenska Academy at University of Gothenburg Department of Internal Medicine and Clinical NutritionAbstractTitle: Alpha-linolenic acid from flaxseed oil and effects on blood pressure ? A systematic reviewAuthor: Christine Hårdfelt och Liduina van SitterenSupervisor: Helen LindqvistExaminer: Anna WinkvistProgramme: Dietician study programme, 180/240 ECTSType of paper: Examination paper, 15 hpDate: April 9th, 2014Background: High blood pressure is strongly associated with an increased risk of developing cardiovascular disease, particularly stroke. ALA-fatty acids have previously been associated with decreased blood pressure. Flaxseed oil is very rich in these fatty acids and has also been highlighted as an affordable and sustainable source.Objective: To investigate whether ALA-fatty acids from flaxseed oil may affect blood pressure in people with high risk for cardiovascular disease.Search strategy: Two searches in PubMed and Scopus were performed. The sample was specified by using specific keywords.Selection criteria: The criteria for inclusion of studies required that flaxseed oil was compared with a control and that blood pressure was measured as an endpoint.

Celiac disease (CD) is an autoimmune disease, induced by an immune mediated reaction in the small intestine after ingestion of gluten and related prolamines. There is a strong genetic linkage and most important are the genes that encodes for HLA-DQ2 and HLA-DQ8. The European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) has developed new guidelines for investigation of CD in children and adolescents, which include genotyping for HLA-DQ2 and HLA-DQ8. Therefore, the clinical microbiological laboratory in Västmanland wants to introduce a method for analysis of these genes. Microarray is a newly developed method for determination of the alleles HLA-DQA1 and HLA-DQB1 that encodes for the ?- and ?-subunits of the HLA-molecules.

Bakterien Brenneria salicis lever i xylemet hos bland annat arter av Salix. Under vissa omständigheter ger den upphov till en vissnesjuka, internationellt känd som Watermark Disease. Utbrott av denna har aldrig rapporterats från Sverige, men då forskning visat att bakterien ofta uppträder som endofyt och inte patogen uppstår frågan om själva bakterien ändå inte finns i Sverige utan att orsaka vissnesjuka. Samma forskning visar nämligen att yttre faktorer kan förmå bakterien att övergå från en endofytisk till en patogen livsstil. Under antagandet att klimat och markanvändning är sådana faktorer och vetskapen att de är i förändring blir det angeläget att undersöka B.

Pyometra is a common and life threatening disease of intact bitches. The disease is caused by a hormonal influence on the uterus in combination with a bacterial infection. The most common treatment is ovariohysterectomy, but several medical options are available to maintain fertility or avoid surgery and anaesthesia. Drugs that can be used for medical treatment are for example progesterone-receptor antagonists, prostaglandins and dopamine agonist. The present study focused on treatment with the progesterone-receptor antagonistaglepristone in combination with antimicrobial therapy.

Benskörhet (osteoporos) och frakturer orsakade av osteoporos är ett stort globalt problem. Syftet med det tioåriga projektet ?Vadstena en benhård kommun? var att utvärdera om man med en befolkningsinriktad interventionsstrategi kunde minska osteoporos och osteoporosrelaterade frakturer i en kommun. Ett representativt urval av befolkningen i åldern 20-79 år, 15% av en population på 7800 personer, blev tillfrågade om att delta vid fyra undersökningstillfällen som innebar att fylla i en enkät och att bentäthetsmätas. Vid första tillfället deltog 70%, första uppföljningen 69%, andra uppföljningen 79% och vid den tredje uppföljningen 65%.Syftet med denna MPH-uppsats är att beskriva det praktiska interventionsarbetet utifrån dagboksanteckningar och att presentera befolkningens upplevelser av interventionsarbetet.Vi nådde uppskattningsvis 5000 personer (65%) av befolkningen med direkt information.De personer som fick individuella riskprofiler baserade på angivna svar i frågeformulär och bentäthetsvärden var de som gav mest positiv respons och kan tillskrivas en lyckad individuell intervention.Den grupp som varit med en eller flera gånger tidigare (interventionsgruppen) var de som vid sista undersökningen 1999, hade fått ökad kunskap om osteoporos (P<0,001).

A zoonosis is a disease or infection that is naturally transmitted between vertebrate animals and humans. The majority of infectious diseases that affect humans are zoonoses. Environments where wild animals, domestic animals and humans live in close proximity with no or small boundaries in the ecological system favor the transmission of diseases between animals and humans. The above described situation is more common in low income countries, where humans and animals live in high density and zoonoses are generally more common. The study was conducted in Cambodia.

Myxomatous mitral valve disease is a common disease in older dogs of small- to medium-size breeds. The mitral valve, and less commonly the tricuspid valve may be affected which causes them to leak blood from the ventricle to the atrium of the heart during systole. With increasing severity of mitral valve leakage the forward stroke volume ejected into the aorta decreases, which may lead to an increase in blood pressure in the pulmonary vein resulting in pulmonary edema. A decrease in cardiac output may lead to a decrease in blood pressure, but the body may respond in order to normalize the blood pressure. Franzén showed in 2007 that the systolic blood pressure was increased in dogs with severe mitral insufficiency.

Joint-related diseases including hip dysplasia (HD) and elbow arthritis (ED) can in advance cases lead to that the dog has to be put down, and these diseases are also the cause to expensive veterinary treatments of many large breeds, including Labrador Retrievers. The aim of this study was to make a follow-up study on the 271 Labradors, who previously participated in a study on the effect of nutrition and exercise on hip and elbow status in a birth cohort born year 2000. That study investigated the relationship between nutrition, exercise, and HD and ED. A follow up study on the same dogs at 5-6 years of age investigated the clinical effects of the radiological hip and elbow status at 1 years of age and if was effected by body condition score. This study took place in 2011-2012 and 187 Labrador retrievers participated.

AbstractEvidence based research has shown that organized parent support programmes have a goodeffect in strengthening the role of the parent and preventing problems during growth. Thisin turn has a great significance for Public Health.Komet is one of the evidence based programmes used in Sweden, based on Americanprogrammes and adapted to Swedish conditions.This qualitative study consists of interviews with six children between six and nine yearswith behaviour problems, whose parents have taken part in the Komet programme.With Grounded Theory as research approach the children?s experiences of the programmeand relations within the family have been looked into and analysed.The result of this study suggests that a space for growth of their own is a common need ofthe children, and that this can be achieved by giving them the opportunity to function in afamily environment where they are seen and understood.The Komet programme contributed to this by giving the family tools to strengthen relationswithin the family, create calm and make the children more visible.The self image of the children in this study had improved which gave them more room togrow in a strengthened family situation. This in turn improved conditions for good feelings,and sense of well being, of importance for child development and health..

This article presents a retrospective case study combined with a review of the current literature concerning canine gestational diabetes. A total of 14 cases have been collected from six different clinics in Sweden. There are few previously published reports on canine gestational diabetes. Gestational diabetes is a disease that rarely occurs in pregnant bitches. The condition is due to the rise of progesterone that occurs during the estrus cycle.

The Bovine respiratory syncytial virus (BRSV) causes bronchiolitis and interstitial pneumonia, predominantly in calves, and is a major cause of bovine respiratory disease worldwide. In humans, BRSV is paralleled by the closely related Human respiratory syncytial virus (HRSV), an important cause of respiratory disease, most severe in infants.The clinical signs and pathology during RSV infection is caused, not only by the direct effects of viral replication, but also by the response of the host immune system. The immunopathology of RSV has long obfuscated our understanding of the disease, and development of effective treatment and vaccines will be very difficult until greater knowledge is gained.One of the components of the immune system that has come into focus in RSV research the last few years, is the Toll-like receptor 4 (TLR4). The TLR4 receptor is well known as the receptor that binds lipopolysaccaride (LPS), and initiates the host response to bacterial infection. Recently, it has been shown that the fusion protein of RSV also interacts with, and up-regulates the expression of, the TLR4 receptor.