The WT1 gene is a complex gene originally known to suppress cancer in kidneys. Studies of WT1 knockout mice have confirmed the important role of WT1 in the pathogenesis of Wilms? tumour, a tumour which counts for 95% of all childhood renal tumours. In that case the WT1 gene acts as a tumour suppressor gene. Subsequent research has shown that the WT1 gene in many other cases acts as an oncogene, e g in leukemia or lung cancer (even though these cancer forms can emerge as a result of many other aetiological factors).

The object for this study is a company developing and manufacturing vehicles for heavy transportation. The company distributes their products on a global market. Therefore the company is required to have efficient internal production development processes in order to successfully beat the competition. The purpose of this master thesis is to study how this particular company intends to implement their standardized theoretical product development process within their organization and how well it is done. We intend to identify and specify if the process has any unexploited capacity.

Abstract  The development and onset of diseases such as cardiovascular disease (CVD) and Type 2 diabetes are closely linked to genetics and lifestyle factors including physical activity and diet. A cluster of metabolic disorders called the metabolic syndrome (MetS) is a high-risk factor in developing these diseases. Acording to the International diabetes institute, one fourth of the worlds adult population has MetS. These individuals are twice as likely to die from CVDs compared to individuals without MetS. Physical activity (PA) and exercise has been shown to provide a number of positive effects that are considered to reduce the risk of developing sickness and premature mortality among both men and women of all ages, independent of other risk factors.

This thesis has been performed at the system development company Verendus System AB, together with the home care company Basic Care Unit (BCU).The thesis has consisted of developing a web based informationsystem for BCU in which they can administrate their business. At the time of writing this thesis, BCU was using a windows-application to administrate their activities, which was both costly aswell as resulting in an unnecessary burden. The aim the thesis has thus been to create a platform-independent information system that simplifies and streamlines BCUs work by being user-friendly aswell as imposing some simplifying features.The students has been developing the system by the help of a work method they themselves developed. The method consisted of working in several iterations that each had several milestones. The method resulted in the students knowing easily when each iteration was finished or not.The thesis resulted in a working platform independent prototype.

This work has been made in cooperation with the municipality of Eslöv and the inventory area is a part of the deepening of the municipality plan of east Eslöv. The aim of the work is to test the principle of balance in the overall planning. Later in the detailed planning process a more detailed calculation is made and a suggestion of suitable measures for compensation is made. Then the method with green area factors can be used. The goal is to balance the negative influence on the environment from the planned impacts to gain a sustainable development of the city. The principle of balance means that the one responsible for the development also has to compensate for the negative impacts on nature and landscape that comes with the development.

The comprehensive aim of the essay is to discuss the abilities of developing individual, communicative and cooperative skills, related to The Swedish National Agency for Education, for pre-school children in Montessori and Reggio Emilia-inspired pre-schools. The importance of the choice of pre-school for lifelong learning is discussed and examined. The two educational profiles are presented and the theories of communication, collaboration and individual work are the basis for the analysis of the results. The collection of empirical data is done through observations and interviews with pre-school children. First, the informants construct a fantasy animal on their own and then together with a partner.

The purpose of my examination is contributing with knowledge about the relation between language- stimulation in preschool and read- and writes developing and teachers thought about that. In order to meet the purpose I read literature that deals with my matter and is based previous research. I also made qualitative interviews with three elementary school teachers and three preschool teachers who work within preschools that concentrate on development of language in a town in the middle of Sweden.  In this way I find out about their thoughts about what they think is important to work with about language in preschool and how the preschool teachers can work with the development of language to make it easier for the children in their read- and writes developing. The result shows that it is important to work with children?s development of language in preschool.

How affected are the sugar production in Mozambique and Tanzania by EU sugar regime? What does the EU sugar reform constitute in these countries?Using theories regarding free trade and anti-free trade, I am able to answer these questions. The aim of this paper is to study how the various sugar agreements with EU affect the sugar production in Mozambique and Tanzania. Therefore I am using a method called a most similar system design in this comparative case study. The conclusion is that the EU sugar regime is the main reason to how the sugar productions in developing countries are.

Human Computer Interaction (HCI) is a broad discipline that studies different concerns regarding interactive systems? development. One of the major interest points within the discipline is the reasoning behind building specific functionality into computers and the long-term effects that usage of systems will have on humans.Within Human Computer Interaction there are theories and frameworks how to involve a user in the process of developing new systems. In this paper focus is applied to the development process within developing applications for Enterprice Digital Assistants (EDA) and to what extent the end-users are involved in the process. Fazer Bageri AB has been choosen to represent a business corporation that uses handheld computers in their everyday tasks.The method used to gather information for this study has been by performing interviews and observations with key stakeholders at Fazer Bageri AB and MobiOne AB.

Resource-based learning or problem-oriented learning are teaching methods that are becoming more and more common in schools today. In order to make these teaching methods work there is a demand to make students information literate. The aim of this thesis is to find out how six teachers at six senior high schools apprehend their professional role of seeking, preparing and developing the course in history of literature. I have used phenomenography which is both a set of theoretical assumptions and a methodology. This means that by doing a limited number of qualitative interviews one is able to describe the variations of the conceptions that have emerged.

The Swedish automotive industry has since way back been struggling with bankruptcy, abroad buy outs and staff cuts. Competition and pressure on prices are two factors that affect the automotive industry. Because of this, the companies are pressured to continuously developing their work in addition to be able to compete on the market. The aircraft industry has successfully managed to implement additive manufacturing (AM) and for motorsport has several components manufactured with AM been used. When AM is used as a manufacturing method, there are a number of advantagesthat follows.

This thesis has been performed at the system development company Verendus System AB, together with the home care company Basic Care Unit (BCU).The thesis has consisted of developing a web based informationsystem for BCU in which they can administrate their business. At the time of writing this thesis, BCU was using a windows-application to administrate their activities, which was both costly aswell as resulting in an unnecessary burden. The aim the thesis has thus been to create a platform-independent information system that simplifies and streamlines BCUs work by being user-friendly aswell as imposing some simplifying features.The students has been developing the system by the help of a work method they themselves developed. The method consisted of working in several iterations that each had several milestones. The method resulted in the students knowing easily when each iteration was finished or not.The thesis resulted in a working platform independent prototype.

This thesis describes the universalization, improvement and further development of acompact crane support frame for flatbed trucks. The work has been conducted at Eloch Fordonsteknik AB (henceforth EFAB) in Uppsala.The aim of the work has been to shorten the assembly time of the product. By doingso, the product can be kept on shelf, which in turn results in shorter lead time. Thishas been done by universalizing the support frame to be compatible with most of thechassis EFAB works with. Additionally, the entire construction has been made lighter,which will make it a more attractive choice for customers.A pre-study was conducted and information was gathered internally, as well asexternally, in order to ascertain that no limitation or possibility was overlookedduring the course of the project.One such limitation has been the geometry of the truck bed that the support frameshall be compatible with.

This thesis investigates in which way principles and theories of usability is revelant when evaluating interactive systems for children aged 10-12. It also investigates whether there are specific factors that you should keep in mind while developing interactive products for the targeted group.The results of the qualitative study shows that priciples and theories of usability is relevant when evaluating interactive systems for the targeted group. However there is one concept that is more significant than the others. Our study shows that our targeted group is sensitive to time-consuming activities such as loading times etc. which has to do with the efficiency of the system.

Design for Six Sigma (DFSS) is a further development of the Six Sigma draft to carry through preventing quality measures in developing and designing of new products and processes. With increasing demands on enterprises development processes to be more safety and faster the need of DFSS arise as a product, process and service development concept in the organisations. Design for Six Sigma aims to improve and structure the development process of an organisation and consider the application of the innovation problem solving. The concept aims to leave the structure of the traditional Six Sigma concept and instead, from an innovative perspective, search for new solutions to existing problems. The concept constitute of a toolbox with a lot of quality tools that are divided into phases in a development model.