Till alla godkända läkemedel skall bifogas information till vårdpersonal hur produkten skall användas säkert och effektivt. De metoder som används för insamling av data under en klinisk läkemedelsprövning, innan godkännande för försäljning, påverkar möjligheten att göra korrekta bedömningar av ett läkemedels bieffekter. Insamling av patientsäkerhets-relaterad data, ?incidenter? (?Adverse Events?; AEs), i kliniska läkemedelsprövningar är ett område förenat med många metodiska oklarheter och svårigheter. Internationella och nationella regelverk specificerar inte i detalj hur datainsamling skall utföras.

Statens väg- och transportforskningsinstitut (VTI) utför tillämpad forsknings- och utveck-lingsverksamhet inom samtliga transportslag. Inom VTI genomförs ett antal olika projekt inom en stor variation av områden. Det kan handla om t.ex. människors beteende i trafiken, en körbanas hållbarhet eller, som denna rapport handlar om, trafikflödet över en viss geografisk punkt under ett förutbestämt tidsspann.Detta gör att en stor varierad mängd data produceras inom de olika avdelningarna då VTI har ca 35 olika testsystem och instrument som producerar mycket varierad data. Data kan be-stå av allt från relativt enkla heltalsserier till stora komplexa matriser.

Purpose: The purpose of this study is to examine the difference in return between Swedish and Russian hedge funds while considering the risk taken.Method: This study is based on quantitative data on funds' historical returns from the electronic database Morningstar.se. Additional data is taken from the funds websites, the Swedish National Bank and Fondbolagens förening.Result and conclusion: All hedge funds, both the Russian and Swedish performed better thanthe index. The Russian hedge funds nevertheless performed better than their Swedishcounterparts in all three evaluation methods..

New method for measuring road quality- A statisticalstudy of the relationship between road quality andsocioeconomic development A new tool with implications for road maintenance has the potential to yield statistical data for road quality in a large number of regions. This thesis investigates the possibility to develop a method, from this data, for evaluating the effects of road quality on socioeconomic development.The thesis is essentially divided into two parts. Part one looks to qualitatively establish the link between socioeconomic development and road quality and the second part focuses on how to develop a method for evaluating the effects of road quality on socioeconomic development. A method was devised using categorical data and a multinomial regression model. This method provides a comprehensive overview of the complex relationship between a variety of different variables.

This report summarizes the development of a calculation program estimating the profitability of converting a peak-load oil-fired boiler to pellets. To convert an oil-fired boiler to pellets a new fuel handling system must be designed. Changes also have to be made to some other components. Since there are many different techniques for transportation, storage and treatment of the fuel only the most interesting techniques from Swecos experience and interest were included in the study.The capacity of the different parts in the system was dimensioned based on the power of the boiler after conversion. To estimate prices, installed power and dimensions manufacturers and distributers were contacted.

Allt större och större andel företag väljer att presentera och förmedla varor och tjänster via e-handel. En viktig aspekt vid e-handel är att kunden känner förtroende för e-handelsapplikationen och företaget. Denna rapport redogör för vilken inverkan multimediala inslag har för förtroendet av en e-handelsapplikation, vid initialt användande. En undersökning har genomförts med hjälp av en kooperativ utvärdering av fyra e-handelsapplikationer vilka innehåller olika typer av multimediala inslag har.Resultatet av undersökningen visar att multimediala inslag inverkar positivt på förtroendet för e-handelsapplikationer. Däremot finns indikationer på att för hög grad av multimedialt inslag inverkar negativt på förtroendet för e-handelsapplikationer..

The present study investigates the relationship between narcissism, using identified facets in the five-factor model for the grandiose and vulnerable narcissistic personality, and job performance. The results, based on analyses of correlations from previous studies, meta-analyses and norm-data, show general differences regarding the grandiose and vulnerable narcissistic facet profile and their respective relationship to job performance. The results confirm previous study implications of the facet level data?s ability to capture aspects of the personality that a broader measure misses. Similarly, the results demonstrated that facets could differentially predict job performance in both a negative and positive direction.

The aim of this thesis is to investigate the electric solar potential on the Swedish island Gotland. The Gotlandic habitations have been divided into four house categories. For each category energy demand, roof area, geographic orientation androof tilt have been decided. Solar radiation data have been collected from the Swedish solar radiation model STRÃ…NG (STRÃ…NG, 2012).The buildings characteristics and the solar radiation have been used as input values in common solar formulas, the solar potential for each building category have been summed up to a total electric solar potential for the region.The electric solar potential on Gotland was calculated to 242 GWh/year with solar data from 2010. Gotlands largest city, Visby, is marked as cultural heritage by UNESCO (UNESCO, 2012).

Background: According to us, obtaining reimbursement of expenses in connection with a representation is a ?forgotten? process, and we therefore find it interesting to look further into. In some cases we have not claimed for compensation since we consider the process as too complicated or that we lost the original receipt. Ernst & Young (2009) say in their research that within the financial management area, Swedish operations loses billions of Swedish crowns due to bad routines. Okada and Hoch (2004) mention that if time were not considered as a resource, time would not be a hinder.

Thesis purpose The study aims to examine the effects vertical and horizontal line extensions might have on the total parent brand equity in terms of strength and its baseline product regarding of market share, loyalty and penetration under an elapsed period of time. The study aims to investigate a number of actual conducted line extensions effect on the above mentioned aspects of Kellers (1993) definition of brand strength as a part of the total brand equity. Methodology The effect of a number of line extensions of the parent brands and the baseline products is being examined in terms of market share, loyalty rate, cannibalization and market penetration. The thesis is focused on the correlations between these different parameters during a certain elapsed time ratio in order to test our theoretically routed hypothesizes in a deductive manner. Occasional correlations are derived from an indexation of data collected from the Gfk database. Theoretical perspective The study is derived from Kapferers (2004) definition of brand equity, where he is dividing the concept into three parts. This study is focused on Brand strength in particular, which is one of the parameters in the above-mentioned theory.

This master thesis has been done at Enea Epact AB. The purpose of this thesis is to develop and implement a Link Quality Control algorithm for GPRS/EPGRS in the current testing tool. A Link Quality Control (LQC) shall take quality values from mobile stations and base stations and decide a codingsscheme that opimizes the throughput of data. The Advantage with LQC is that it adapts the used coding scheme to the channel quality. If the channel quality is too bad for the used coding scheme, a slower coding scheme with more redundancy should be selected.

I det här arbetet har jag undersökt möjligheten att synkronisera lagrad kalenderdata mellan två olika system.Mitt arbete beskriver ett API, som i ena änden kommunicerar med Xcerion Baxide-Web Services, och i den andra änden med en mobil enhet med implementerat stöd för Exchange ActiveSync (t.ex. en iPhone eller Android).Med hjälp av Exchange ActiveSync-protokollet kan man synkronisera bland annat kalender, kontakter, e-post, anteckningar och påminnelser mellan flera klienter genom en Exchange Server. Dock hamnade all implementation utöver kalendersynkronisationen av Exchange ActiveSync redan från början utanför examensarbetets ramar.Microsoft tillhandahåller en mycket detaljerad dokumentation över Exchange ActiveSyncprotokollet. Dessutom, bland annat med hjälp av Microsoft Exchange Server 2010 och programmetWireShark kunde trafiken från en redan fungerande implementation av protokollet avlyssnas.Kommunikationen mellan en klient och en Exchange Server kan antingen ske över HTTP eller HTTPS där data transporteras kodat i WBXML. Av säkerhetsskäl är det dock rekommenderat att en Exchange Server inte tillåter trafik över HTTP.Innan själva implementationen analyserades protokollets struktur samt vilka nödvändiga metoder som behövdes för kalendersynkronisationen.

High quality within a Lean production system begins with standardised work, which creates stable processes able to generate predictable output. If nonconformity from the standard procedures occurs, routines are needed to analyse, correct and prevent the nonconformity from occurring again. In that way, the nonconformity can be a trigger for continuous improvements toward more stable processes. In takted production lines, where the operator follows a standard sequence with tasks set to be completed within the takt time, a nonconformity leads to downtime in the operator?s sequence, and no value is added.

Flygets utsläpp skall reduceras med 50 % till år 2050, ? flygbranschen måste därför möjligöra för alternativa lösningar. Taxfreevarornas hanter-ing är en av flera behjälpliga lösningar som kan innebära miljö- och eko-nomiska vinster för flygbolagen Ett annat kontribut av en förändring är säkrare flygningar, både för kabinpersonalen och resenärerna. Uppsatsen forskningsfrågor är följande:Vilka orsaker bidrar till att taxfreehantering-en inte har förändrats? Hur kan innehållet och utvecklingen av tilläggs-tjänsten beskrivas och förstås? Hur ser konsumtionsbeteendet ut hos svenska flygresenärerna beträffande taxfreevaror? SyfteUppsatsens syfte är att bidra med kunskap om varför taxfreehanteringen inte har förändrats.

The aim of this study is through a teacher perspective illustrate and analyze how preschool teachers apprehend children´s learning in relation to the preschool yard.The main research questions asked were:How do preschool teachers apprehend the preschool yard in reference to it as a place?In what way do preschool teachers use the preschool yard in their work with the children?How do preschool teachers view the preschool yard and the significance it has on children´s learning?The research is based on data collected through interviews and observations at four different preschools in the same municipality. The research views place and people as social constructions, a theory of knowledge that is based on the view that the world, places and people are constructed in relation to each other. This perspective as well as previous research is used for analyzing the data collected through a qualitive study based on interviews. The data analyzed show that the preschool teachers involved in this research apprehend the preschool yard as a central part in the learning of young children.