In a time of economic turmoil and financial crisis profitability matters rise higher and higher on company agendas. Many companies are pressured to find profitability to avoid layoffs or even bankruptcy. Profitability essentially depends on the margin on the product or service sold and the costs associated with selling these products or services and hence these areas are of vital importance if companies are to improve profitability. Previous research has focused, for the most part, on product profitability while customer profitability has received less attention. This study is based on a case study of a Swedish publishing house and aims to investigate how the company?s Cost-to-Serve varies between its distribution channels.

This thesis has been focused around the Diels Alder reaction with the goal to design an enzyme catalyzed reaction pathway. To achieve this goal computer aided enzyme design was utilized. Common traditional methods of computational chemistry (B3LYP, MP2) do not do well when calculating reaction barriers or even reaction energies for the Diels Alder reaction. New calcu- lation methods were developed and tested. This was the focus of the first part of the thesis, by choosing a small system, extensive and heavy calculations could be done with CBS-QB3.

 The luxury market has steadily grown from the industrial revolution and onwards. Changes in society, trends and the increased living standards has enabled more people to consume luxury goods.The world is going through a major economic crisis at the moment. Studies shows that companies that have focused on added value rather than lowering prices has survived past financial crisis. It is also obvious that companies act very different during times of crisis. Adding to the problem is trends that point to a more careful consumption and environmental awareness.

The aim of this study was to compare the effect between the drugs rituximab and infliximab in rheumatoid arthritis (RA). RA is an autoimmune disease that affects the peripheral joints and is associated with exacerbations. Various immune reactions in the body cause inflammation of the joints which further results in cartilage and bone damage. The diagnosis is made by the classification system "The 2010 American College of Rheumatology (ACR) / European league against rheumatism (EULAR) classification criteria for rheumatoid arthritis", which is an update of the older system called "The 1987 American College of Rheumatology classification criteria for RA". Approximately 0.5-1% of the population is developing the disease, but it varies slightly between different parts of the world.

Background: The prevalence of dementia increases both in Sweden and in the rest of the world. People with dementia often display some types of behavioral and psychological symptoms. These symptoms include, among other things, aggressiveness, inactivity, activity disturbance, anxiety, hallucinations and depression. The symptoms can create a negative impact of those with dementia, their caregivers and their next of kin. Aim: To describe the effect of non-pharmacological treatments have on the behavioral and psychological symptoms of people with dementia.

During the past twenty years the immigration to Sweden has changed significantly. Earlier immigration mainly focused at filling the vacancies in the Swedish industry, today immigrants primarily come to Sweden as Refugees. This change of immigration combined with the restructuring of the Swedish industrial sector has resulted in great a deterioration of the chances for immigrants to gain entry to the Swedish labor market.This study aims at examining how the cooperation between authorities in the municipal of Hörby in Sweden fosters integration. The study primarily examines how the cooperation between authorities in a integration project can contribute to a better integration to the labor market.Through a qualitative study, five persons who occupy important roles in the project have been interviewed. The results of these interviews have been complemented by internal documents as well as extern material to validate the results.The most important findings that have been revealed are the importance of language in the process of gaining entrance to the Swedish labor market.

This report is a study of Swedish traditional ships and their safety organization. The focus is on how the non-profit organizations that operate the traditional ships can adapt to current regulations in the best way. Initially a background on traditional ships, their organization and regulations that regulates them will be presented.The study is focused on which parts that can be more important in the safety organizations for traditional ships. The questions also includes if a non-profit organization might affect the safety and how the role as designated person should be handled in these organizations. Furthermore the study addresses how a non-profit organization that operates traditional ships might improve their safety organization.The information is gathered by interviews with persons that work with safety, controls safety organizations or is active in organizations that operate traditional ships.

The purpose of this essay has been to study the different discourses that are expressed in social welfare secretaries? assertions when they assess cases with elements of honour-related violence, intimidation and oppression. To do so I have used a discourse analysis theory and technique, based on three qualitative interviews with social welfare secretaries. The interviews were focused on vignettes, which were all fictitious cases with various elements of honour-related violence. One of the interviews was a focus groupinterview with four participants, while the other two interviews were individual.

In many of the world's countries, there is a national organization responsible for marketingthat country as a tourist destination. Through their offices, these organizations work towardsthe creation of effective strategies and a deeper understanding of local markets. Usingqualitative methods such as interviews, observations, and thematic analysis, we managed toinvestigate how the Czech and the German national tourist offices operate, and whatstrategies they are implementing to increase the volume of tourism. The study focused on theanalysis and comparison of the organizations' goals and communication channels.The results show that the investigated tourist boards operate in a similar manner with smalldifferences concerning choice of strategies and communication channels. These discrepanciescan be partly explained by differences in the organization's ownership forms and theconsequences that follow that fact.

Old people's life situation when receiving municipal help and care in theirlast period of life is sparsely investigated from their own perspective. Thepurpose of this study was focused on the thoughts of the aged people andtheir personal experiences on what quality is within the geriatric care. Inthis qualitative study, 10 elderly people aged 75-90 years wereinterviewed from 3 different nursing homes within Solna Municipality.Qualitative interviews, with the emphasis on their present life situationespecially what brought about a good life, were performed. The interviewswere analysed using qualitative content analysis. The implication of theterm ?meaningful existence? is individual and differs from person toperson.

Syftet med föreliggande litteraturstudie var att beskriva på vilket sätt licensierade vårdhundar kan fungera som ett komplement i omvårdnaden av barn med autismspektrumtillstånd. Syftet var också att beskriva kvaliteten av artiklarna utifrån den metodologiska aspekten urval. En litteraturstudie med deskriptiv ansats genomfördes utifrån två artiklar med kvalitativ ansats, två artiklar med kvantitativ ansats, fyra artiklar med kvalitativ ansats och kvantitativa mätningar, samt två artiklar med kvantitativ ansats och kvalitativa inslag i form av observationer. De inkluderade artiklarna hade publicerats mellan åren 1989 och 2013. De databaser som användes för artikelsökningen var Academic Search Elite, Cinahl och PubMed med sökorden: Dogs, Child, Autism Spectrum Disorders, Animal-assisted, Service dogs, Autism samt Therapy Dogs.

The aim of the study is to gain a deeper understanding of how young people's current identity is affected by their criminal background. We also want to understand the impact of resources in these young people?s social networks (that is their social capital) on their life course and formation and reformation of their identity. The theoretical frameworks used (as a tool to be able to analyze the empirical data) are theories of stigma, identity and social capital. The empirical study was conducted using semi-structured interviews that focused on questions about the life-story of informants.

The purpose of this study was to examine how teachers practice Arne Tragetons theory of using computers as the first writing instrument in reading and writing development. We wanted to clarify how the work from using Tragetons theory was applied while investigating if and how other methods of reading and writing instruction were used. Our interest lays in how the teachers accomplished the knowledge of this theory and also how the choice of this approach came about. To investigate this we used interviews with a qualitative nature, where seven active teachers were interviewed. They worked in three different schools in years one to three, they were all women and had various long experiences of work on the computer writing tools.

BackgroundNumber of patients treated with medicine that has an anticoagulation character is constantly increasing. Chronic atrial fibrillation is the most common diagnosis being treated, but other diagnoses such as venous thrombosis), pulmonary embolism, stroke, coronary stent thrombosis and arterial thrombosis treated. There are a variety of anticoagulant drugs. In Sweden Warfarin is used as standard medicine for oral anticoagulation therapy.PurposeThe purpose of this study is to examine and reflect nurses' experiences of working on anticoagulation clinic, and if he / she claims to have access to the necessary skills and resources to carry out a safe care.DesignThe study has a qualitative design with semi-structured interviews which were analyzed with an inductive approach. The interviews included six respondents.FindingsThe results showed that nurses who worked at anticoagulation Clinics had no specific training to operate these clinics.

How do we perceive literature? In our times computer games and Internet have made us grow more comfortable to the usage of non linear storylines. But how does this apply to printed literature?In this essay, called ?From a to b through d h and o. Non linear storytelling in our time? I have focused on nonlinear literature from different time periods and I have studied novels such as James Joyce?s Ulysses as well as works by William S.