Equine metabolic syndrome (EMS) it?s a clinical condition that includes obesity, regional adiposity, insulin resistance (IR) and laminitis. A similar syndrome exists in human medi-cine, the metabolic syndrome (MS), were systemic hypertension also is a prominent fea-ture. The systemic hypertension seen in humans with MS is partly due to a vascular endo-thelial dysfunction with an enhanced endothelin-1 (ET-1) mediated vasoconstriction. There are indications that systemic hypertension might be a feature in EMS as well but if ET-1 is involved in the development of the systemic hypertension in horses is not known.

ABSTRAKTSyfte och mål: Att jämföra olika tekniker vid trakeal intubering av obesa patienter. Bakgrund: Fetma blir vanligare och behovet av kunskap inom vården ökar för att på ett säkert sätt ta hand om dessa patientgrupper. Anestesisjuksköterskan ska kunna hantera, prioritera och ta snabba beslut vid akuta tillstånd och förebygga komplikationer som kan uppstå. Kunskap och beredskap inför akuta situationer är av stor vikt för att hantera den svåra luftvägen och kunna ge en god och säker omvårdnad genom anestesin.                                                                   Design: En litteraturstudie med kvantitativ ansats genomfördes.

The incidence of many of the most common diseases in dairy cattle has been proven to be highest during the time closest to calving. It is possible that the current breeding strategy with 12 month calving intervals increases the risk for disease in dairy cattle, which is problematic concerning both animal welfare and for economic reasons. The economic incentives behind a calving interval of 12 to 13 months have mainly been based on milk- and feed- costs and no costs due to diseases or fertility disturbances have been included.The aim of this study was to see if a lengthening of the calving interval would result in lower disease frequency. The hypothesis is that cows with a planned calving interval of 15 months have a lower disease incidence than cows with a calving interval of 12 months due to less number of calvings. Therefore the difference in disease frequency should be larger when compared over a long period of time, such as over lifetime, since cows with a longer calving interval experience fewer calvings.The study was performed between August 17th, 1994, and January 24th, 2007.

AbstractTitle: The debut of gluten ? Does timing of gluten introduction affect the risk ofceliac disease in high-risk children?Author: Sandra Hagwall Frohm and Maria IngmarSupervisor: Frode SlindeExaminer: Mette AxelsenProgramme: Programme in dietetics, 180/240 ECTSType of paper: Bachelor?s thesis in clinical nutrition, 15 hpDate: May 26, 2015Background: Celiac disease is a chronic disease in which the intestinal mucosa is damaged bygluten exposure, and the only treatment is a lifelong gluten-free diet. The disease affects about1 % of the population worldwide, but the majority are undiagnosed. Ingestion of gluten and thegenotype HLA-DQ2/8 are required for disease development, although additional genetic andenvironmental factors are believed to be of importance. One hypothesis is that timing of glutenintroduction in infants affects the disease risk.

Atopic dermatitis (AD) is a complex, often lifelong allergic disease affecting around 10 % of both dogs and humans. The hallmark symptom is severe pruritus, causing a lowered quality of life. Mast cells (MCs) are known to play an important part of the immunopathogenesis, promoting a faulty T helper cell type 2 (Th-2) response which follows by a production of specific immunoglobulin E (IgE) antibodies towards environmental allergens (Ag). To further investigate the role of MCs and its mediators in the progression of AD, a low-calcemic vitamin D3 analog (MC903) was used to induce AD-like symptoms locally on the ears of two different knock-out (KO) mouse strains. The first strain was Wsh-/- mice deficient in MCs.

Diabetes mellitus is a rising epidemic throughout the world and there is currently great interest in quantifying the beta-cell mass (BCM) in vivo non-invasively. In the present experiment, the feasibility of in vivo imaging of the glucagon-like peptide-1 receptor (GLP-1R) in beta-cells was examined, using the positron emission tomography (PET) tracer [68Ga]Ga-DO3A-VS-Cys40-exendin-4 as a marker, in native pancreatic beta-cells of a porcine diabetic animal model and healthy controls. Eight Swedish high-health domestic pigs were randomly assigned to be either controls or made diabetic using streptozotocin (STZ). The experiment proceeded during eight weeks, starting with an acclimatisation period. Once the pigs had been socialised they underwent surgery for the insertion of a jugular vein catheter, allowing induction of diabetes with STZ, intravenous (i.v.) injections and stress-free blood sampling. Development of diabetes was confirmed by clinical examinations, blood glucose values and insulin-staining of pancreatic sections post mortem. The diabetic pigs were insulin treated and responded well.

Sahlgrenska Academy at University of GothenburgDepartment of Internal Medicine and Clinical Nutrition3AbstractTitle: How does isoflavones in combination with soy protein impact cholesterol levels in hypercholesterolemic postmenopausal women relative to milk protein?Author: Emma Edberg och Emma NilssonSupervisor: Lena HulthénExaminer: Anna WinkvistProgramme: Dietician stydy programme,180/240 hpType of paper: Examination paper, 15 hpDate: 2014-05-26Background: Hypercholesterolemia is a major risk factor for cardiovascular disease and the number one cause of death among women in Western countries. Declining levels of estrogen at menopause could be a contribution factor. Isoflavones is a vegetable substance, with structural and functional similarities to the human estrogen. This is a potential reason for possible cholesterol-lowering effects.

Gastric and intestinal disorders are common and costly human health problems worldwide. Helicobacter pylori are a gram-negative, pathogen bacteria and the most common cause of duodenal and gastric ulcer in the stomach the intestinal mucosa. Prolonged infection and colonization can lead to chronic gastritis and stomach cancer. H. pylori are present in the gastric and intestinal mucosa of half of the world population and a relation between infection and low socioeconomic status has been shown.

Porcine circovirus type 2 (PCV2) is a common virus present in most parts of the world. PCV2 has been pointed out as the major causative agent to post weaning multisystemic wasting syndrome (PMWS) that affects pigs after weaning. The clinical symptoms of PMWS are impaired growth, diarrhoea, respiratory problems and increased mortality. At autopsy enlarged lymph nodes with depletion of lymphocytes are commonly found. Since 1991 PMWS has spread all over the world and was first described among Swedish pigs in 2003. Although PCV2 is widespread, only some pigs develop PCV2-related diseases. Why this is and what other factors that are required in order for the disease to develop is yet unknown. The main theories involve other infections, for example PRRS, and management issues but also genetic differences between pigs and/or virus strains have been suggested.

Sahlgrenska Academyat University of GothenburgDepartment of Internal Medicine and Clinical NutritionAbstractTitle: The effect of naturally existent beta-glucan in adults with hypercholesterolemia. - a systematic review with focus on the Swedish food market.Author: Ida Edman Hellberg, Frida HanssonSupervisor: Mette AxelsenExaminer: Anna WinkvistProgramme: Dietician study programme, 180/240 ECTSType of paper: Examination paper, 15 hpDate: May 01, 2014Background EFSA states in 2010 that there are good evidence that three grams of beta-glucan/day from oat as a part of a balanced diet, has a positive effect on total cholesterol and LDL.Objective Evaluate if there is evidence for primary treatment of lifestyle related hypercholesterolemia with products naturally containing beta-glucan.Search strategyIn February 2014 the databases PubMed and Scopus were used for article research. The search terms used were; cholesterol level, beta-glucan, hypercholesterolemia, oat and barley.Selection criteria Articles, written in Swedish and English, on RCT-studies conducted on otherwise healthy adults with hypercholesterolemia (serum cholesterol >5,0 mmol/L) were included. The intervention product must naturally contain beta-glucan, and an equally product should be retailed in Swedish grocery stores. The control group needed to be supplied with a placebo product and the participants could not be on any lipid-lowering medication.

Kattpest är sjukdom orsakat av felint panleukopenivirus (FPV), vilket är ett smittoämne som regelbundet ger upphov till sjukdomsutbrott både inom Sverige och i övriga världen. Sjukdomen drabbar främst unga individer där en mortalitet över 90 % kan observeras. Gällande fetal och neonatal infektion har FPV en affinitet för nervceller och infektionen ger klassiskt upphov till cerebellär hypoplasi. Infektionen yttrar sig med neurologiska symptom som ataxi, hypermetriska rörelser, inkordination, tremor och blindhet. Gällande adulta individer påvisar FPV istället en affinitet för celler i benmärg, gastrointestinalkanal och lymfoid vävnad, vilket inducerar immunosuppression, panleukopeni och segmentell enterit.

Inflammatory airway disease (IAD) is a respiratory disorder that most commonly affects young horses performing at a high level. The clinical signs are often mild but the disorder can cause a marked decrease in performance to a point where the horse has to be taken of training and competing. The aetiology underlying IAD is not yet fully understood. One current theory is that a type I-hypersensitivity reaction due to allergens in the environment is the cause in some horses. The most reliable diagnostic method is a bronchoalveolar lavage (BAL) since it reflects the inflammatory status in the most distal parts of the lungs, which are affected in IAD.

Working as a veterinary nurse includes advising animal owners, helping them to make discisions through well-based facts and experience. Preemptive spaying of the healthy bitch brings many advantages and disadvantages. It leads to cessation of gonadal hormone production, and how the exact extent the surgery affects the dog is not yet fully understood. The sex hormones mainly control the reproductive system, but receptors of these hormones are found in many tissues of the body, and have complex relationships with other hormone systems. Spaying decreases the metabolism although the bitch gets an increased appetite, which enhance the risk of obesity, unless the owner restricts food intake.

Milk fever, or parturient paresis, is the second most common disease in Swedish dairy cows. The disorder is associated with the onset of lactation when some cows are unable to meet the metabolic demands of calcium to support milk production and therefore develop a state of hypocalcaemia. Clinical hypocalcaemia (milk fever) may lead to coma and death in severe cases but subclinical hypocalcaemia has also been shown to have negative effects on e.g. feed intake and production and to increase the susceptibility of the cow to develop secondary diseases. The nutritional strategy applied precalving is of great importance in preventing milk fever and e.g.

Equestrian sports and the interest in horses have existed for hundreds of years. It is only in the last thirty years the technological development have enabled closer studies of equine locomotion. The production of both soft- and hardware that manages to capture and analyze the fast movement of the horse has resulted in a large increase in locomotion research. Even though the interest in horses and the different disciplines they compete in is great, there is a small understanding in how the rider influences the movement of the horse in different types of training. There are several studies available where horses moving freely without the influence of a rider have been studied. What happens with locomotion and ground reaction forces when a rider and equipment are added is not well studied. The objective of this study was to investigate if there are any differences in the ground reaction forces between sitting and rising trot. The study contained seven horses. Six Grand Prix dressage horses and one dressage horse competing at intermediate level.