Clopidogrel is an antiplatelet substance that prevents blood coagulation in the arteries. It is an inactive pro drug that becomes activated after first-pass metabolism by the liver. The active metabolite of clopidogrel is 2-oxoclopidogrel, which is unstable therefore pharmacokinetic data is obtained by measuring the inactive metabolite clopidogrel acid in plasma. Clopidogrel is taken orally in tablet form. The aim of this project was to develop a LC-MS/MS method for quantification of clopidogrel and its metabolite in plasma. The method has been developed by optimizing the sample preparation.

Nanofiltration is a proper way of preparation of drinking water. The process has a lot in common with reverse osmosis where a semipermeable membrane is used to separate a pure water flow from the remaining water. A pilot plant was used to ensure that nanofiltration is a suitable technology for a specific waterworks station in Glemmingebro, Ystad. The purpose was also to find out if a pH-adjustment is needed for feed water in a possible full scale plant.  In this case nanofiltration is used mainly to remove sulphate and calcium since the raw water contains concentrations of these substances which exceed the limits for potable water. It is important to receive a high recovery (RC), otherwise the deliviery of water won?t be high enough.

Preventive measurements as well as clinical caries diagnostics are vital to retain a good dental health in the population. In order for optimal caries diagnostics radiographs are used. There is a great intra- and intervariation regarding cariesprogression. A large number of tools for cariesprevention at home or in the clinic are today used. The aim of this journal study was to compare the progression of carieslesions in the approximal area, diagnosed on radiographs, and preventive measures used to reduce cariesprogression between two examine dates on two dental clinics.

Drinking water is produced from raw water and is either from groundwater or surface water. This thesis aims to find out if the cleaning process of raw water is sufficiently effective. This is important because consumers are otherwise at risk of waterborne infection caused by pathogens. There are three groups of pathogens; bacteria, virus and parasite. These have different characteristics which mean that they require different water treatment to be separated.

Drinking water is produced from raw water and is either from groundwater or surface water. This thesis aims to find out if the cleaning process of raw water is sufficiently effective. This is important because consumers are otherwise at risk of waterborne infection caused by pathogens. There are three groups of pathogens; bacteria, virus and parasite. These have different characteristics which mean that they require different water treatment to be separated.

This report is a thesis on requests from Sandvik Mining and Construction (SMC) in autumn of 2012. The goal of this work was to study the feasibility of creating and implementing an Equalized preventive maintenance program in SMC maintenance operations and reduce downtime for preventive maintenance (PM). To investigate whether this was possible, the authors studied the current procedures for the PM. The authors have collected and analyzed all relevant information within the maintenance department reporting system as well as through interviews determined whether it is practical to introduce a Equalized PM programs. The authors had also studied the possibilities to entrust part of the maintenance work to the operators of the machine cells.

The purpose of this essay is to investigate how parents of children with ADHD or autism experience the transition between preschool and preschool classes. To get answers to my questions, I interviewed five parents representing three different schools in one municipality. I have chosen to use a qualitative research interview inspired by phenomenology. The results of this study show that parents perceptions differ, in terms of how well the transition work for children, and how support and treatment are at a transition. For children with a documented diagnosis, schools have an action plan for those in the gray area there are no procedures.

Kulturvårdscentrum was a project that had great significance for local folklore societies in Bohuslän.Bohusläns museum was i charge of the project that lasted from 1987 until about 2001 when most ofthe original staff have retired. The staff was mainly recruited from a large shipyard, Uddevallavarvet,at it's closure due to recession. Financing was largely made by the government to help outthose unemployed who otherwise should have a hard time finding a new job. At start there was about25 employees who where trained for one year by staff from Swedish museums, conservation studios,and teachers the university. The education was aimed at serving local folklore societies, and dealingwith their special problems.

The aim of this research is to develop a better understanding of how preschool-teachers respond to children in preschool, when they show that they want to have some influence. I have concentrated this study on how the preschool-teachers respond to the children in the gatherings and when the children are playing freely indoors, where the questions at issue are:How do the preschool-teachers respond to the children?s initiative for participation in the gathering and while playing freely?There have been four preschool-teachers and 14 children who have taken part in this study. The children who took part are in the ages of three to five. The study was done at a section in a preschool in middle Sweden.The method used in this study is unstructured observations.

Compressed air is a low efficiency media, and is thus very expensive to produce. This thesis work began by mind mapping how to create savings on the compressed air system at Billerud Skärblacka AB. Certain issues have been chosen for further studies.In order to identify the consumption of compressed air at PM 8 and 9, several measurements were made. At PM 8 there were not found any pressure drop, only large pressure variations for short periods of time. The causes of these pressure variations were not established.

Drinking water is produced from raw water and is either from groundwater or surface water. This thesis aims to find out if the cleaning process of raw water is sufficiently effective. This is important because consumers are otherwise at risk of waterborne infection caused by pathogens. There are three groups of pathogens; bacteria, virus and parasite. These have different characteristics which mean that they require different water treatment to be separated.

The wastewater treatment plant at GE Healthcare's facility in Uppsala deployed a three step vacuum evaporator in 2007. The purpose of this was to pre-treat wastewater containing amines. The purpose of this thesis was to optimize thisprocess by reducing the amount of concentrate without releasing more nitrogen tothe environment and to examine if density could be used as a measurement of whenthe process should be ended.To create a foundation for optimization six test cycles were conducted with samples taken from all three steps. Both concentrate and condensate were tested as well as the incoming solution. Furthermore, the thesis has been expanded with a benchmarking part examining two different evaporators.

Large areas have been ditched in Sweden during the past 100 years to improve the forest production. Ditching and also maintenance of old ditches are operations having mainly negative effects on water quality, flora and fauna and changing characteristics of soil. The purpose of this study was to suggest a method for inventory of the need for ditching maintenance in old forest ditches that takes biodiversity, water protection and forest production into consideration. Inventory methods from five Swedish and Finnish forest companies, agencies and organisations were compared. Their employees were interviewed about their handling with ditches, forest production and nature conservation.

Consumer generated advertising is a new phenomenon in the landscape of communication. Tools such as the Internet enable the consumer to create and spread messages for brands without the permission or control of the brand owner. We carried out a quantitative experiment to investigate the effects of how companies choose to handle these activities as well as how expectations of these consumer generated ads differ from traditional advertising. The findings show that strong brands may benefit from these activities if handled the right way and the brand owner adapts it?s reaction to the content of the ad.

The aim of this research is to develop a better understanding of how preschool-teachers respond to children in preschool, when they show that they want to have some influence. I have concentrated this study on how the preschool-teachers respond to the children in the gatherings and when the children are playing freely indoors, where the questions at issue are:How do the preschool-teachers respond to the children?s initiative for participation in the gathering and while playing freely?There have been four preschool-teachers and 14 children who have taken part in this study. The children who took part are in the ages of three to five. The study was done at a section in a preschool in middle Sweden.The method used in this study is unstructured observations.