Syftet med denna litteraturstudie var att enligt vetenskapliga studier, publicerade mellan år 2002 och 2007, beskriva omvårdnad av patienter med kronisk hjärtsvikt. Metoden som användes var en litteraturstudie med beskrivande design. Information hämtades från databaserna Medline, Academic Search Elite och Cochrane Library, samt ur Vård i Nordens webbarkiv. Sökorden som användes var ?chronic heart failure? och ?nursing?.

Amyotrophic lateral sclerosis is a progressive neurological disease which causes a slow degeneration of the body. Living with this disease means being exposed to severe strain and every day could bring new losses. Amyotrophic lateral sclerosis does not cause any harm to the intellect, the mind remains unaffected. The aim of this study was to achieve an understanding, and to shed light on the nature of positive life experiences of people living with amyotrophic lateral sclerosis. This literature study is based on detailed examination of three person's narrations taken from their autobiography and biographies.

Diabetes typ 2 är en kronisk sjukdom som ständigt ökar. Syftet med denna litteraturstudie var att beskriva patienters upplevelser av att leva med diabetes typ 2. Nio vetenskapliga artiklar analyserades. Analysen resulterade i fem huvudkategorier; upplevelser av att ändra livsstil, coping - ett sätt att hantera sin diabetes, upplevelser av en förändrad självkänsla, upplevelser av vårdpersonalens bemötande och framtidssyn. Resultat som framkom i studien var svårigheter med att ändra livsstil beträffande kostvanor, hantering av medicinering och fysisk aktivitet.

The purpose of this study was to describe how adolescents aged 12-18 years with inflammatory bowel disease experience their illness and what coping strategies they use to manage their illness and improve their wellbeing. The method used was a descriptive literature study, and the result of the study included 15 scientific articles. Our results showed that IBD affected the adolescent?s everyday life and social life with friends, family and activities. The adolescents also reported that they experienced a feeling of vulnerability, altered body image and that they saw themselves as different from healthy subjects.

The purpose of this degree project is to clarify how five Kenyan Life Skills teachers discuss about hiv and aids education. Furthermore, to reveal whether the validity claims in their verbal communication refers to facts, morality or personal experiences. This, I will study by examine the teachers knowledge of, and attitudes towards, the disease. The teaching methods they are using and the basis of their validity claims. I have chosen to use semi-structured interviews as method and the theoretical framework is based on Jürgen Habermas theory of universal pragmatics.My result shows that there is a dilemma about whether the respondents knowledge is sufficient or insufficient.

Breast cancer is the most common tumor disease among women in Sweden. About 7000persons, having a median age of 65, are diagnosed each year with this disease. Withmammography screening, breast cancer can be detected in an early stage which improves theoverall survival (OS). 20-30 % of the breast cancer tumors are overexpressing humanepidermal growth factor receptor 2 (HER2), which is a protein that stimulates cell proliferation.Trastuzumab (Herceptin®) is a humanised monoclonal antibody that targets the HER2-proteinand prevent the signals for cell proliferation.Trastuzumab has earlier been used for treatment of metastatic breast cancer. In the year of 2007trastuzumab was approved for adjuvant treatment of patients who has been medicated withsurgery and/or radiation.The aim of this study was to investigate the effects of adjuvant treatment with trastuzumab inHER2-positive breast cancer patients.

Most of the people in today's society have at least some knowledge about Alzheimer's disease to some extent. When a person with Alzheimer's disease is being taken care of at home, the relatives have to change their own priorities and readapt themselves to the existing situation. The primary aim of this study is to describe how the relatives experience their own situation in life. The secondary aim of this study is to describe how the relatives understand their own relation with the health care authorities concerning the help and support issues. The authors have realized this study using the analytic inductive method and have interviewed four informants using a semi structured interview guide.

Breast cancer is the most common tumor disease among women in Sweden. About 7000persons, having a median age of 65, are diagnosed each year with this disease. Withmammography screening, breast cancer can be detected in an early stage which improves theoverall survival (OS). 20-30 % of the breast cancer tumors are overexpressing humanepidermal growth factor receptor 2 (HER2), which is a protein that stimulates cell proliferation.Trastuzumab (Herceptin®) is a humanised monoclonal antibody that targets the HER2-proteinand prevent the signals for cell proliferation.Trastuzumab has earlier been used for treatment of metastatic breast cancer. In the year of 2007trastuzumab was approved for adjuvant treatment of patients who has been medicated withsurgery and/or radiation.The aim of this study was to investigate the effects of adjuvant treatment with trastuzumab inHER2-positive breast cancer patients.

Kroniska bensår är en både tids- och kostnadskrävande åkomma för samhället och ger sänkt livskvalitet för de drabbade. Läkningstiden kan variera från några månader upp till flera decennier och det finns inte i dag någon given behandlingsmetod. Elektrisk nervstimulering är en vedertagen metod för smärtlindring som i viss utsträckning även används med syfte att förbättra sårläkning vid kroniska bensår. Kunskaperna om dess användbarhet är dock dåligt spridd bland vård- och rehabpersonal. Syftet var att skapa en överblick av den publicerade litteraturen gällande elektrisk nervstimulering som kompletterande behandling vid kronsikt bensår.

This literature study describes the ways in which the spread of rabies can be prevented in India, what guidelines are set and also which methods have proved most effective. Every year rabies causes the death of around 20 000 people in India, which makes the prevalence in the country the highest in the world. The main source for human infection is bite wounds from infected dogs. People and animals can be vaccinated both prophylactic and post-exposure prophylactic (PEP), despite this the disease continues to claim high number of victims. The majority of those dying are young men and children from the poorer part of the population. Knowledge among the Indian population on rabies and its transmission routes, wound care and vaccinations is very limited.

Hypertrophic cardiomyopathy (HCM) is the most common heart disease in cats. Maine coon is one of the breeds where the disease is overrepresented. Studies have shown that HCM is inherited as an autosomal dominant trait in Maine Coon cats. This finding has led to cardiac screening using ultrasound in the breed. The results of the screening are used in a national breeding program constructed to reduce the spread and incidence of HCM in Maine Coon cats.

Establishing a reference interval for plasma fibrinogen in foals Fibrinogen concentrations were analysed in EDTA preserved blood plasma samples from 34 thoroughbred foals born in 2001 and 2002 at one stud farm. The foals were between 0 and 240 days old at the time of the sampling, and there were 19 fillies and 12 stallions in the group. The foals were examined for clinical symptoms of disease and their body temperature was measured before blood was sampled from the jugular vein. From totally 156 blood samples, 31 were selected as originating from clinically healthy foals, and used to determine a reference range for thoroughbred foals. Samples originating from foals showing clinical symptoms of disease or an abnormal body temperature at the time of sampling, were classified as coming from unhealthy animals.

Introduction The genetic skin disease epidermolytic ichtyosis is caused by mutations in either keratin gene 1 or 10 and leads to blisters and hyperkeratosis of the epidermis. At cellular level the disease is seen as aggregates in the keratin filaments. Since medicines are hard to investigate and produce mainly due to lack of reproducible model systems, there is no good treatment available for this disease today. In this article we describe how an in vitro model consisting of cells from a stable cell line transfected with expression plasmids to mimic patient cells, may be a possible alternative for screening compounds for therapies. The first step was to generate an expression plasmid required to complete the in vitro model.

The aim of the study was to describe what it's like to live with Multiple Sclerosis (MS) and experiences of social support and being received and met by health personnel. The method was a qualitative interview study of descriptive design and was analyzed using qualitative content analysis. Three women and two men (26-75 years) with MS from two municipalitiesin central Sweden participated in the study. The main results showed that the participants felt the disease limited everyday life. The majority described feelings of injustice being affectedby the illness, but they now have a new perspective on life.

Syftet med studien var att beskriva hälsorelaterad livskvalitet, ångest/depression och vårdtillfredsställelse hos kvinnor med bröstcancer tidigt i sjukdomsförloppet samt att undersöka om det fanns ett samband mellan dessa aspekter. Vidare studerades förklarande bakgrundsfaktorer; demografiska, socioekonomiska och medicinska faktorer samt psykosocialt stöd. Denna tvärsnittsstudie genomfördes som en enkätstudie kompletterat med medicinska data från Regionalt register för bröstcancer i Uppsala/Örebroregionen. Totalt 1574 förfrågningar om deltagande gick ut, varav 69 % valde att delta i studien. Niohundratrettiotvå kvinnor ingick i de slutliga analyserna (59 %).