The Bovine respiratory syncytial virus (BRSV) causes bronchiolitis and interstitial pneumonia, predominantly in calves, and is a major cause of bovine respiratory disease worldwide. In humans, BRSV is paralleled by the closely related Human respiratory syncytial virus (HRSV), an important cause of respiratory disease, most severe in infants.The clinical signs and pathology during RSV infection is caused, not only by the direct effects of viral replication, but also by the response of the host immune system. The immunopathology of RSV has long obfuscated our understanding of the disease, and development of effective treatment and vaccines will be very difficult until greater knowledge is gained.One of the components of the immune system that has come into focus in RSV research the last few years, is the Toll-like receptor 4 (TLR4). The TLR4 receptor is well known as the receptor that binds lipopolysaccaride (LPS), and initiates the host response to bacterial infection. Recently, it has been shown that the fusion protein of RSV also interacts with, and up-regulates the expression of, the TLR4 receptor.

Background: Type 2 diabetes is a disease which causes vascular damage, stroke and premature death.Oxidative stress may play a role in the development of insulin resistance and diabetes. Selenium is amineral involved in the protection against oxidative stress, and has been thought to be favorable in theprevention of the disease. However, this has changed since trials observed positive correlationsbetween high selenium levels and incidence of type 2 diabetes.Objective: To examine the studies that investigates seleniums effect on the incidence of typ 2 diabetesSearch strategy: Searches have been done in PubMed and Scopus.Selection criteria: Included studies were human studies in English/Swedish with RCT or cohortdesign with the aim to investigate the correlation between selenium and incidence of type 2 diabetes.Excluded studies were studies whose aim was to investigate the role of selenium in patients withexisting diabetes. Studies regarding pregnant women, animals or children and with in vitro design werealso excluded. Of the studies found in Scopus where MeSH terms were available, the ones who did notinclude relevant terms were excluded.Data collection and analysis: Studies were collected according to the aforementioned criteria.

ABSTRACT Epilepsy describes a neurologically caused condition which involves seizures. Epilepsy can be classified according to different types of causes and the nature of seizures can vary. Medication for epilepsy in dogs is limited in comparison with human medicine. Idiopathic epilepsy is the most common neurological disease and one of the most common genetic diseases in dogs. Because epilepsy has a higher prevalence in certain breeds, there is reason to suspect that it is a hereditary disease. The inheritance of idiopathic epilepsy is for most breeds not determined, except for a few variants of the disease.

Haptoglobin is an acute phase protein with important biological role because of its capacity to bind to haemoglobin. Haptoglobin exists in three major genetic polymorphism types: Hp1-1, Hp2-1 and Hp2-2, the distribution of which has been associated with abdominal aortic aneurysm (AAA), an asymptomatic aortic disease common among men older than 65 years.    Five different electrophoretic methods were tested according to their ability to separate the haptoglobin phenotypes. The detection was based on a produced hemolysate of blood in which haemoglobin binds to haptoglobin thereby forming a complex that can be detected by specific haemoglobin staining using TMB-dihydrochloride and hydro peroxide as substrate resulting in an azure-green color of the bands. Samples from 15 patients who had suffered surgery for not broken AAA, that is more than5.0 cmaortic diameter, and 15 samples from matched controls were analyzed.    Among the five tested electrophoretic methods best migration and separation was seen on the pre-cast agarosgel Hydragel HR on the instrument Hydrasys. The other four methods gave less successful results.

The prime aim of this thesis was to investigate whether high or low iodine intake during certain periods of life was, or was not a strong risk factor for the development of canine lymphocytic thyroiditis (CLT). And secondly, if a high or low selenium intake in a combination with high or low iodine intake also may have an influence on that risk factor. To investigate this, a dietary questionnaire was sent out to dog owners. The dogs were selected from an ongoing genetic study of CLT. The questions investigated brand and type of feed during different life stages (puppy, junior and adult) and also if there were any use of dietary supplements.

Background: Breast cancer is one of the most common types of cancer in the world and it usually affects elderly women. However, there are between 600-700 cases per year in Sweden where women under the age of 45 are diagnosed. Removal of the breast or part of the breast, hair loss, fatigue and nausea as a result of the breast cancer treatment has an emotional and physical impact on the women?s lifeworld. The nurse should build a relationship with the women to identify and meet their needs. Aim: To describe younger women?s experiences of getting a breast cancer diagnosis and life afterwards.Method: Four biographical books were analyzed to match the aim of the study.Result: The findings were that the women experience similar thoughts and feelings when it comes to living with a cancer diagnosis.

The aim of this study was to describe the importance of diet and physical activity related to Diabetes Mellitus (diabetes). Method used was a descriptive literature study based on empirical studies. The study shows that diet, physical activity and lifestyle-changes are very important factors when it comes to preventing and treating of diabetes. By the right diet and physical activity the treatment with medications in some cases can be superfluous and people with the disease could live longer and be healthier during their lifetime. Nurses have the responsibility to educate, inform and make sure that the diabetic patient gets the best care as possible specially suited for this individual patient.

Hjärt-kärlsjukdom är idag en av de största folksjukdomarna i Sverige med högst mortalitet till följd. Flera studier visar att uppföljning av patienter, informationsbehov och stöd till patienter efter utskrivning från sjukhusen till primärvården är otillfredsställande. Det finns endast ett fåtal studier som visar på patienternas egna upplevelser av att leva med hjärtinfarkt. För att kunna förbättra vården till dessa patienter är det viktigt att ta del av patienternas egna upplevelser av att leva med en hjärtsjukdom. Syftet med studien är att beskriva patienters upplevelser av att leva med hjärtsjukdom ur ett patient- och livsvärldsperspektiv. Metoden i studien är kvalitativ intervju.

Hypertrophic cardiomyopathy (HCM) is the most commonly diagnosed cardiac disease in cats. The phenotype varies from mild focal thickening to severe concentric hypertrophy at the left ventricle. Two separate myosin binding protein C (MYBPC3) mutations have been identified in Maine coon cats (A31P and A74T) and one in Ragdoll cats. All three of them seem to cause familial HCM in an autosomal dominant pattern. The purpose of this study was to investigate the presence of these three mutations in population cats of different breeds with HCM in Sweden. The results may show if HCM is present in the absence of these mutations.

Background: Contracting asexually transmitted disease is strongly associated with stigmaand shame. Stigma associated with these diseases has a significant impact on self-image andpropensityto seek care. Despitehigh incidencethere is a generallack of awareness about therisks and theeffectsthatthese diseases have on both mental and physical health. Health carepersonnel are experiencing difficulties to meet and care for these patients. Aim: The aim ofthis studyisto describe patients'experiences of health care after they were diagnosed with asexually transmitted disease.

Different forms of relaxing methods can be used in rehabilitation for individuals with tinnitus and Ménièré?s disease. Research continues to find convincing proof of effects from the different methods. This study presents methods of relaxing, massage and Mindfulness, as possible complementary rehabilitation tools.The purpose of this study was to investigate opinions about relaxing from professionals working with hearing care. A qualitative approach with phenomenological influence was chosen for the study.

Successful broiler production in hot climates requires knowledge of how birds are affected by heat stress. It is important with access to water and good ventilation to facilitate coping with the heat. It may be useful to reduce the consumption of feed during the hottest hours of the days, which together with a few hours of extra light available could improve both productivity and animal welfare. The vision in birds is superior to that of humans and most other mammals. Continuous light and light with low intensity can cause eye injuries, affect the eye development in young chicken negatively, as well as provide increased incidence of foot pad lesions. Access to light affects the production but also the welfare of birds.

Background: Atopic eczema has increased in the last decade among children. The nurse can have a major role to prevent the disease. Aim: the aim of this study as to describe the nurses´ work in primary care with prevention to families with atopi with focus on atopic eczema among children. Method: A literature review based on analysis of fifteen scientific articles was done. Results: If the child was breastfed both positive and negative effects were evident.

The price trend on rapeseed the latest years has led to an increasing interest to grow the crop among many farmers in Sweden. The price trend has resulted in more than a doubling of the oilseed area since the early 2000s. For many farmers it is an advantage to increase cultivation of rapeseed because of the high proportion of cereals in the crop rotation on many farms, but it is not just benefits. The risk of the fields being infected by clubroot increases within frequent rapeseed cultivation and it often leads to subtantial economic losses. Clubroot is caused by Plasmodiophora brassicae that is a soilborne pathogen in genus Protozoa and its resting spores can be found in the soil for up to 18 years.

Background: More than half of the elderly (65-84 years) in Sweden have problems with hearing. In some studiesit?s discussed if age related hearing loss or presbyacusis is a part of natural aging or if it depends on underlyingfactors.The purpose of this literature study was to analyse scientific papers which illustrate correlations between lessknown underlying factors and presbyacusis, defined from psychoacoustic and/or neurofysiological tests.Material and method; Literature study where scientific papers, relevant to the purpose of the study and thequestions at issue were found in the database PubMed.The result shows that cardiovascular disease, hormones, diet and drugs have an influence on presbyacusis. Thehealth condition of the individual and their lifestyle matters, likewise estrogen which according to the results of 2studies has a protective effect on hearing.Conclusion; The studies show that heart attack and high systolic blood pressure in women have a correlation topresbyacusis, but not in men, - the hormone estrogen, - some vitamins, antioxidants and diet have a protectiveeffect on hearing and studies show that smoking and alcohol have negative effects..