The purpose of this work is to do an investigation on the customers in the pharmaceutical sector; mainly general physicians who have taken part in the education events have any impact in their prescription behaviour after the participation in the program. The settings for this study are general practitioners in the Swedish market who have taken part in the education program held by Novo Nordisk in the treatment of diabetes disease. Methodology: The methodological approach adopted for this work is quantitative; using secondary data from the internal database from the company. The analytical model is tested through statistical analysis using the data?s obtained from the databases.

Inflammatory bowel disease (IBD) är ett samlingsnamn för en grupp inflammatoriska tarmsjukdomar och en av de vanligaste orsakerna till kroniska mag-tarmsymtom hos hund. Orsakerna till IBD är inte helt fastställda men tarmslemhinnans immunförsvar, bakterieflora, genetiska faktorer och miljöfaktorer anses vara centrala för tillståndet. En av de mest utbredda uppfattningarna är att sjukdomen uppkommer som ett resultat av bristande immunologisk tolerans som gör att immunförsvaret felaktigt går till attack mot harmlösa antigen. Syftet med den här litteraturstudien var att undersöka vilken roll Pattern recognition receptors (PRRs) har i IBD, hur tarmbarriären påverkar risken för sjukdomen, vilka förändringar av tarmfloran som setts hos IBD-hundar och hur floran påverkar sjukdomsuppkomst. Litteraturen menar att en defekt tarmbarriär är en av de nyckelfaktorer som hör ihop med IBD. Ökad permeabilitet i tarmen kan öka exponeringen, och därmed interaktion, mellan antigen och immunförsvar vilket inducerar inflammation. Oavsett om en defekt tarmbarriär uppkommer som en effekt av sjukdomen eller om det är en direkt orsak till IBD så är det troligen viktigt för att det ska bli kroniskt.

In this thesis, three separate experiments have been performed on different aspects of the interaction between the causal agent of clubroot, Plasmodiophora brassicae, and its hosts. In the first experiment the pathotype of the P. brassicae single spore isolate, which is currently used to construct a reference genome, has been classified using the ECD bioassay. The disease severity of infected plants was scored according to two different scales and the pathotype was determined according to three previously published guidelines. The results were compared to previous published studies describing the e3 isolate. The life cycle of P. brassicae is not well understood.

Background Calprotectin is a protein expressed in the cytoplasm inside the neutrophile granulocytes. During inflammatory bowel disease (IBD), the neutrophile granulocytes are involved in a complex interaction at the inflammatory area where they die and release their content into the intestinal lumen. Therefore, calprotectin in stool is a suitable marker for diagnosis and measurement of the disease-activity in patients with IBD. The most commonly used method to detect calprotectin in stool is ELISA, but the process of manual preparation of stool samples is time-consuming.Aim The objective of the study was to evaluate an extraction method that could replace manual preparation of fecal samples and to compare different methods for measuring Calprotectin in stool using two ELISA-methods from two manufacturers and one rapidtest.Methods For extraction of calprotectin from stool samples we used sample collector tubes from Epitope Diagnostics and fecal preparation kits from Roche. Two different ELISA-kits for measuring calprotectin concentration in stool were compared.

The aim of our thesis was to describe how the connection between co-dependent relatives and the alcohol-dependent influences the family into changes in their teamwork.Our purpose was also to answer the following questions: How is it living with an alcoholic? Are there any differences in how men and women feel and behave in their relationship with an alcoholic? Are factors like cultural belonging, genre or social class important for how the co-dependent relatives feels and behaves and handle their co-dependency?To answer these questions we made twelve thematic qualitative interviews with six adult children to alcoholics and six people married to alcoholics. We compared the results of these interviews with earlier research. We also applied System Theory and Goffman's Role Theory, as well as Bourdieu´s Capital and Habitus concept.We believe that co-dependency is a family divergence that is very similar to family disease, but that a change in attitude can trigger recovery. According to the interviews many spouses stand by their alcoholic husbands and do actions that perpetuate the alcoholic dependence and thereby hold back any recovery.

The virus-mediated disease Rift Valley fever (RVF) was discovered during an outbreak in Kenya in the 1930s. Since then it has spread to most parts of Sub-Saharan Africa, and in the last decades several outbreaks have caused economic and health issues in Africa, Yemen and Saudi-Arabia. The disease mainly affects domestic livestock, causing abortions, but is also a zoonosis. To be able to control the spread of the disease it is important with surveillance for better knowledge about the distribution and virus circulation even in inter-epidemic/epizootic periods. The human population is growing, and people and their livestock constantly move closer to areas with wild animals which act as reservoirs for different viruses. Also, humans and their animals often get within reach for arthropod vectors, hosting or carrying viruses.

The objective of this study is to understand how people with psychiatric diseases who are enrolled at a psychiatric clinic experience the recovery process and which internal motivations and external factors influence the process. The study is based on interviews with five people who have been enrolled at a psychiatric clinic. Another aim of the study is to understand how the importance of the outpatient care for the personal recovery and the improvement opportunities of the support from the rehabilitation unit that the interviewees see. The study is qualitative and abductive approach was chosen. This means that the study is based on empirical data supported by established theories.

Syftet med studien var att ta fram en utvecklingskurva för internationella toppsimmare inom simsättet frisim. Målet var att ta fram en generell utvecklingskurva för de fem åren innan en simmare uppnår 900 FINA-poäng första gången. Ytterligare en målsättning var att ta fram en mall för vilka nivåer en viss FINA-poäng motsvarar på internationella tävlingar d.v.s. vad som krävs för att placera sig som 8:e, 16:e samt sista kvaltiden till de stora internationella mästerskapen. Frågeställningar:Hur ser den generella utvecklingskurvan för Europeiska simmare ut 5 år innan de uppnår 900 FINA-poäng första gången?Vad motsvarar tävlingskval på SM, EM, VM & OS mätt i FINA-poäng i respektive grenar? Vilka FINA-poäng krävs för att sluta som topp 16 respektive topp 8 på SM, EM,VM samt OS i respektive grenar under de senaste mästerskapen?Finns det någon skillnad mellan de olika frisimsdistanserna?Metod: Resultattider för åren 2011-2014 sammanställdes med hjälp utav Swimrankings.net.

Bacillus anthracis is the causative agent of anthrax, a serious and globally distributed zoonosis affecting a wide range of wild and domestic animals, invariably also humans. However, although known to humans since biblical times, much remains to be elucidated concerning the ecology and transmission of this bacterium. Of particular interest is the Bacillus anthracis spore, the uptake of which is the predominant way to contract anthrax and which is legendary for its resilience in the environment and thus crucial for persistence and spread of the disease. Hence, the aim of this study is to review the natural transmission of Bacillus anthracis and investigate potential means by which soil persisting Bacillus anthracis spores reach concentrations sufficient to infect susceptible hosts. When reviewing the literature, three different theories can be distinguished. Firstly, ?the incubator area? hypothesis suggests that favourable soil factors, possibly in association with amoebas, may constitute an environment supporting repeated spore-bacterium-spore cycling, thus increasing the local amount of spores.

Introduction: Sex and education level has demonstrated effects on health status.Osteoarthritis is a widespread disease that causes reduced health-related quality of life and isthe most common reason for total hip replacement. Osteoarthritis was ranked as the 11thhighest contributor to global disability as reported in the Global Burden of Disease 2010.Aim: The aim of this study was to explore how sex and education level together affectedhealth-related quality of life after total hip replacement. The aim was also to examine whatdimensions of EQ-5D that changed.Methods: The study is a prospective observational study with a quantitative approach. Dataconsisted of education level, obtained from Statistics Sweden (SCB) and health-relatedquality of life before and one year after total hip replacement from the Swedish HipArthroplasty Register (SHAR). Health-related quality of life was measured with astandardised instrument, the EQ-5D, and the study population consisted of 39,141 patients.Results: Womens? EQ-5D-value, before and one year after surgery, were lower in alleducational categories compared with men.

The objective of this study is to understand how people with psychiatric diseases who are enrolled at a psychiatric clinic experience the recovery process and which internal motivations and external factors influence the process. The study is based on interviews with five people who have been enrolled at a psychiatric clinic. Another aim of the study is to understand how the importance of the outpatient care for the personal recovery and the improvement opportunities of the support from the rehabilitation unit that the interviewees see. The study is qualitative and abductive approach was chosen. This means that the study is based on empirical data supported by established theories.

Conjunctival swabs from 12 cats in a Swedish animal shelter were analyzed by real-time PCR for FHV-1, Mycoplasma felis and chlamydiae. The purpose of this study was to see whether and to what extent these agents can be detected and if they were detected from cats housed in quarantine or in the adoption department. Samples were first taken upon arrival at the quarantine and then a second sample was taken two weeks after moving to the adoption department, or upon presentation of signs of disease. The cats spent the quarantine period in two separate quarantines: five in a new quarantine (quarantine A) and seven in a room in the old shelter (quarantine B). The difference between these quarantines was that in B the cats were often mixed together ant the hygiene routines were not as good as in quarantine A.

The Swedish Red Polled breed is threatened by extinction and there are only around 1100 animals left. The breed was popular in the early twentieth century, but since then the numbers have steadily decreased. The overall objective of this study was to find out whether there may be economic incentives for preserving the breed. The milk quality properties are of major importance in the production of dairy products. Therefore we would like to establish if the Swedish Red Polled breed carries favourable alleles at loci of relevance for milk quality, to potentially make the breed more interesting for milk production.

Diabetes mellitus type 2 and chronic obstructive pulmonary diseases (COPD) are two of the most common diseases in the world and the amount are increasing. The treatments of these diseases are self care and a change of lifestyle. For this to be successful there is a need for the person to have knowledge about the diseases and a motivation for making changes in his or her lifestyle. Most of this information is given by the district nurse at the health centre. It is important to get a better knowledge of these persons experiences and how they used the information given to them.

On average half of the sows in Swedish piglet producing herds are culledannually. A significant portion of the sows are euthanized because of lameness orparalysis. Young sows and gilts are overrepresented in the category of animals,culled due to injuries in the musculoskeletal system. These injuries cause pain tothe animals. Early culling of sows/gilts also have economical consequences forthe producers.