Mastitis, inflammation in the udder tissue, caused by S. aureus is a big problem in dairy cattle production. It causes suffering for the cow and curing or replacing the infected cow is costly for the farmer. It is known that beef cattle also suffer from mastitis caused by S. aureus.

Juvertumörer är de vanligaste tumörerna hos tikar och det finns olika typer av både benigna och maligna juvertumörer. De hormonella fluktuationerna som sker under östralcykeln driver utvecklingen av juvervävnaden och behandling med progestiner (syntetiska ekvivalenter till progesteron) för uppskjutande av löp har kopplats samman med förekomst av juvertumörer, vilket har lett till ett intresse för den hormonella påverkan på juvertumörutvecklingen. Hormonerna är i sin tur beroende av uttrycket av receptorer för att kunna ha effekt i vävnaden. Syftet med den här litteraturstudien är att utreda uttrycket av hormoner och receptorer för progesteron, tillväxthormon (growth hormone, GH) och insulinliknande tillväxtfaktor (insulin-like growth factor, IGF) i normal juvervävnad och i benigna och maligna tumörer, såväl som deras påverkan på juvertumörutvecklingen. De intracellulära signalvägarna för progesteronreceptorer (PR), GH-receptorer (GHR) och IGF-I-receptorn (IGF-IR) är kopplade till cellproliferation och genreglering. De komplexa nätverken av signalvägar interagerar med varandra och en obalans i uttryck och reglering av hormoner, receptorer eller molekyler i cellen kan leda till att tumörer uppstår. Vid progestinbehandling har ökade nivåer av GH och IGF-I uppmätts och högst nivåer sågs i maligna tumörer.

Syndecan-1 is a cell surface proteoglycan which participates in cell adhesion, differentiation, motility, morphogenesis and intracellular signaling. The two glycosaminoglycans heparan sulfate and chondroitin sulfate are covalently attached to the ectodomain of syndecan-1 via a tetra saccharide linkage sequence. However, the ectodomain can be modified having only one or neither of the glycosaminglycans attached. The glycosaminoglycans are capable of binding ligands such as fibroblast growth factors (FGFs) and support activation of receptors. The ectodomain is proteolytically cleaved from the cell surface by metalloproteinases in a process known as shedding.

The rising demand for electricity and heat raises a big challange for the society and engineers. Many products have been introduced to the market to supply more energy to the energy systems. Absolicon AB is a Swedish company that develops and markets a combined heat and power generating product. The product, Absolicon X10, uses a parabolic trough to concentrate the radiation of the sun onto a receiver. The receiveris equipped with mono crystalline solar cells and is cooled by a circulating liquid media.

Rabies kills about 55 000 people every year and more than 90% of infected humans are considered getting the disease from dog-bites. To control the disease and eventually eliminate human rabies, the most efficient and economic method is to keep the dog population vaccinated. The objective of this thesis was to evaluate the situation of canine rabies in two urban areas in Lilongwe, Malawi, where canine rabies is enzootic. In each area 200 household-interviews were conducted in September and October 2013. Focal points were awareness of the disease, human incidence as well as vaccination coverage in the dog population.

Promoters are genetic elements that facilitate the transcription of a gene and they have been found in front of non-coding RNA (ncRNA) genes in different organ-isms, e.g. the model plant Arabidopsis thaliana. A similar element, DUSE, has been found in front of ncRNAs in the social amoeba Dictyostelium discoideum and a part of this project has been to analyze the function of this putative promoter element through cloning and expression studies. A construct to analyze the func-tion of DUSE was successfully designed and introduced into D. discoideum but full expression studies were not finished because of shortage of time.

Tumour development occurs to a large extent because of dysregulation of the cell cycle. Of particular importance are defects occurring in the G1 phase. The reason why G1 is critical is because of the influence of several signals (external signals as well as cyclins and cdks) on this stage. The G1 phase can be divided into two parts, G1pm and G1ps. Each part has its ?own? restriction point which needs to be passed in order to progress to S phase.

The Swedish potential of electricity production from roof mounted solar panels has been determined in three steps: accessing the existing roof top areas, simulating the amount of electricity solar panels can produce on these areas and finally analyzing how large the necessary economical change is to make the solar cells profitable.The total existing amount of roof top areas are 319 square kilometers and the area distribution follows the distribution of people. This leads to an installed power of 47,9 GW which are expected to produce 49,0 TWh electricity per year. If the quality of the electricity is prioritized the highest the power is reduced to 3,7 GW, generating 3,8 TWh yearly, but if the hosting capacity is calculated from Sweden?s total electricity need, the capacity is 42 TWh per year.Today, solar panels are not profitable in Sweden for houses, even though there is a subsidy of 35 % of the investment costs, discounted in 25 years. The profitability is calculated with a cost of capital of 5 %, a price on electricity of 1 SEK/kWh and an investment cost of 20 SEK/Wp.

Promoters are genetic elements that facilitate the transcription of a gene and they have been found in front of non-coding RNA (ncRNA) genes in different organ-isms, e.g. the model plant Arabidopsis thaliana. A similar element, DUSE, has been found in front of ncRNAs in the social amoeba Dictyostelium discoideum and a part of this project has been to analyze the function of this putative promoter element through cloning and expression studies. A construct to analyze the func-tion of DUSE was successfully designed and introduced into D. discoideum but full expression studies were not finished because of shortage of time.

Promoters are genetic elements that facilitate the transcription of a gene and they have been found in front of non-coding RNA (ncRNA) genes in different organ-isms, e.g. the model plant Arabidopsis thaliana. A similar element, DUSE, has been found in front of ncRNAs in the social amoeba Dictyostelium discoideum and a part of this project has been to analyze the function of this putative promoter element through cloning and expression studies. A construct to analyze the func-tion of DUSE was successfully designed and introduced into D. discoideum but full expression studies were not finished because of shortage of time.

The dog is unique in the way that the adult weight can vary 100 folds between the different breeds. Despite this, most of the breeds reach adult size before two years of age. For the large-breed dogs this means a very rapid growth when some of them can have a weight gain of up to 150 times their birth weight. The most rapid growth occurs when the puppies are between three to six months old and that kind of rapid growth during such a short period of time makes these large-breed puppies very sensitive to deficits and excesses of energy, nutrients and minerals. Some examples can be excess of energy, excess or deficit of minerals such as calcium and phosphorus or deficits of protein. The rapid growth can also make the large-breed puppies predisposed to some diseases affecting the skeletal and joints.

Since 2003 Saudi Arabia is under attack from domestic Al Qaida-cells which, by random shootings of westerners and bombings of compounds and official state buildings, is trying to challenge the stability of the royal regime. According to Al Qaida, the Royal family is attacked because of their friendly relations to the US and for not implementing Islam in the Saudi society as profound as they ought to. Political analyst finds it obvious that the Islamic Al Qaida-cells by terrorism is trying to erode the stability in the kingdom.An important foundation for stability for any government is legitimacy. The aim of this thesis is to examine the royal legitimacy strategy in the state bureaucracy of Saudi Arabia. The question at issue is: how has the royal family constructed the civil, military and religious bureaucracies to maintain and promote stability and legitimacy?The thesis focuses on the on three different units within these three bureaucracies and it surveys the way they are staffed and organized to strengthen and maintain legitimacy for the royal family.

During the period 2002-2012, 74 people committed suicide within the Swedish judicial system. During the same period of time 702 self-destructive actions and suicide attempts were reported. The purpose of this work was to investigate and illuminate the causes which are responsible for individuals committing suicide while in custody or in prison. The theory of this  work is an ethnographic study of a special social context. A study of literature, statistics and earlier scientific research was used in this study.

In today?s society climate change has grown to one of the largest global issues. To reduce emissions of greenhouse gases, large changes of the energy system are required. An increasingly popular solution is investments in local production of renewable energy resources like wind, solar or geothermal power. The following report examines the possibility for implementing a solar power plant on the new hospital Nya Karolinska Solna. Two different technologies for extraction of solar energy has been studied, solar thermal collectors  to meet the need of heating and solar cells to satisfy the need for electricity linked to operating the hospital building.

Canine herpesvirus-1 (CHV-1) är det herpesvirus som är specifikt för hunddjur. I likhet med andra alfaherpesvirus ger det oftast upphov till en ofarlig infektion hos vuxna individer och en dödlig, systemisk infektion hos nyfödda. När den akuta infektionen är över går viruset in i en latent fas. I den latenta fasen finner man vilande virus främst i de lumbosakrala ganglierna, tonsillerna, öronspottkörtlarna och levern. Stress kan få infektionen att reaktiveras. Uppsatsens syfte är att undersöka hur viruset påverkar individer i olika åldrar, sjukdomens effekter på hundaveln och lämpliga åtgärder för att undvika sjukdom. Hos den vuxna individen ses oftast bara lättare luftvägsinfektion, ögoninflammation eller genitala förändringar.