Ataxi är då hunden har svårt att koordinera sina rörelser och orsakas av att nervsystemet inte fungerar som det ska och degenereras. Degeneration av cerebellum och då specifikt purkinjecellerna och granulacellerna ger en form av ataxi kallat cerebellär ataxi. Denna typ av ataxi uppvisas genom att hunden (Canis lupus familiaris) står bredbent, har muskelkramper, obalanserad gång och ögonrullningar. Den genetiska bakgrunden till cerebellär ataxi hos hund finns beskriven hos flera raser, däribland beagle, finsk stövare, old english sheepdog, gordonsetter och coton de tuléar. Hos alla dessa raser nedärvs sjukdomen autosomalt recessivt och de orsakande mutationerna ger olika dysfunktioner inom nervcellerna som gör att de inte kan fungera som de ska och degenereras.

Fryst eller kyld sperma används ofta vid artificiell insemination på hund. Skador kan uppstå på spermierna under frysningsprocessen. För att spermierna ska bibehålla sin viabilitet och undvika skador tillsätts spädningsvätskor som bland annat innehåller sockerarter, antibiotika, glycerol och äggula. Äggula skyddar spermierna mot frysskador och bidrar till en ökad spermieöverlevnad, dock är mekanismen bakom detta ej helt klarlagd. Att äggula ingår i spädningsvätskan kan medföra en risk för mikrobiell kontamination och innebära ett problem vid internationell handel med sperma.

Determination of serum thymidine kinase 1 (TK-1) activity is used as a tumour marker in both human and veterinary medicine. TK-1 is an intracellular enzyme involved in a salvage pathway of DNA synthesis. The expression of TK-1 is cell cycle dependent and the activity increases markedly after the G1 to S transition in the cell cycle and then declines rapidly in G2. The pronounced proliferative activity in tumour cells result in a higher TK-1 enzyme activity within the cell. The fact that the increased TK-1 activity can be measured in serum makes TK-1 a useful marker in diagnostics of neoplastic diseases and it provides information regarding prognosis and treatment effectiveness. In human medicine a radioactive based test is used to determine the TK-1 serum activity.

This thesis within the field of Integrated Product development at the Royal Insitute ofTechnology, performed at Primary Development Dishcare at AB Electrolux, is supposed to finda solution to enhance the hygiene inside an Electrolux dishwasher. The outcomes of this thesisare functional prototypes to evaluate the efficiency of disinfection by the use of Ultra VioletLight and Ozone.The thesis has followed Electrolux Primary Development process, with delivarables andcheckpoints.Ultra violett light with a wavelength of around 264 nm penetrates through the cell wall ofbacteria and micro organisms and causes a molecular rearrangement of the cells DNA. Thisprevent the bacteria from reproducing and it is considered dead. Commonly used UV-C lampstransmits the wavelength 254 nm which is very close to the optimum for germicidal action.A competitive brand have reacently launched a dishwasher claiming to achieve greaterdisinfection with an UV feature. This dishwasher was tested during the thesis and proven tohave a very low effect on the hygienic result.Two prototypes were devolped and tested for UV disinfection of dishware.

During the milling of Sandvik Coromant?s world leading Drill with replaceable inserts,the CoroDrill880©, burrs appear around the milled surfaces. The burrs are removedusing different methods, one of which is deburring with special brushing machines thatare integrated into milling cells. The machines of the type Sinjet, use a Siemensguidance system. The deburring results are not satisfying and manual deburring isrequired afterwards.

SammanfattningBakgrundDet är i Sverige svårt att tillgodose behovet av cirka 450 tjänstehundar och gällande hälsa är uppfattningen bland användarna att hundarnas fysiska hållbarhet blivit sämre. Med hänsyn till att det lider brist på tjänstehundar och att de tas ur tjänst tidigare än önskat vore det av stort värde att kunna förlänga en polishunds tjänstgöringstid. Ett sätt att förverkliga detta kan vara att använda undersökningstekniker vilka tidigt kan fånga upp lindriga förändringar i rörelsesymmetri, förändringar som kan vara ett första tecken på smärta. En tryckmätningsmatta kan registrera små förändringar i hur hunden belastar sina ben, förändringar som är svåra att se med blotta ögat. Det kan därför vara av intresse att ta fram ett normalmaterial för tjänstehundar så att det med tryckmätningsmattans hjälp tidigt går att upptäcka om en stoisk tjänstehund har ett förändrat rörelsemönster.Syfte & hypotesSyftet var att använda en tryckmätningsmatta för att skapa ett normalmaterial för en tjänstehundspopulation gällande parametrar registrerade med tryckmätnings-mattan.

Photovoltaic Systems in Sweden has longbeen heavily dependent on subsidies and grants to bring in a profit for the investor. Production of excess electricity is a major reason for this as the compensation for excess electricity today is low. However, there are businesses that have an electricityneed that are particularly suitable for solar electricity. These businesses have an electricity demand when the sun shines the brightest and if the Photovoltaic System is properly scaled, the excess electricity can be minimized. A golf club is that kind of a business and this thesis aims to examinate the solar power potential for golf businesses in Sweden.Nine golf clubs was selected from different locations in Sweden.

Since early civilization, herbal tea has been used as remedies for an abundance of different diseases. Among these herbal remedies, peppermint (Mentha piperita) was used for its effect on bowel related ailments. Even though peppermint was not described until late 17th century, it has been used since 1000 years before Christ by the Egyptians. In present day it is still considered a remedy for stomach pain etcetera, and much of the recent research is concentrated on the positive effects of peppermint on pain and bowel diseases. A large section of the research is also reviewing positive effects of peppermint on cancer, allergy and also on its potential as antibacterial agent.

Working as a veterinary nurse includes advising animal owners, helping them to make discisions through well-based facts and experience. Preemptive spaying of the healthy bitch brings many advantages and disadvantages. It leads to cessation of gonadal hormone production, and how the exact extent the surgery affects the dog is not yet fully understood. The sex hormones mainly control the reproductive system, but receptors of these hormones are found in many tissues of the body, and have complex relationships with other hormone systems. Spaying decreases the metabolism although the bitch gets an increased appetite, which enhance the risk of obesity, unless the owner restricts food intake.

Bergvik Skog is one of the leading forest companies in Sweden who use airborne laser scanning for forestry information. They utilize laser data retrieved by the Swedish National Land Survey to describe the forest holdings and facilitate planning for thinning and final felling operations. However, the possibility to identify stands with clearing needs by using laser scanning data has not been tested in a large scale. The data used in the current study are field data from The Swedish National Forest Inventory in combination with laser data from the Swedish National Land Survey acquired in 2009. The collected data is used to find one or several laser variables that best describe the relationship of the field measured samples with clearing needs.

Bröstcancer/juvertumörer hör till de vanligast förekommande tumörsjukdomarna hos människa, hund och katt, men vad som orsakar uppkomsten av sjukdomen är till största delen okänt. Hos möss har man funnit ett virus ? MMTV ? som orsakande faktor. MMTV, Murine Mammary Tumor Virus, är ett retrovirus som kan verka som ett endogent virus eller som exogent agens med möjlighet att nedärvas till avkomman, bland annat via modersmjölk. Infektion sker via aktivering av B-celler, T-celler och andra lymfocyter som tar sig till juvervävnaden och infekterar denna.

Today, buildings utilize 40 % of the total energy consumption. New energyrestrictions and directives have entered the construction industry. Photovoltaic is asustainable, clean and quiet solution that integrates well in the urban environment buthave not yet reached a breakthrough on the Swedish market. The conditions for solarenergy production are often set in the early planning stages where they rarely arebeing prioritized.This master of engineering project focuses on identifying problems regardingimplementation of photovoltaic in city development projects and giving suggestions topossible improvements in the planning- and construction process. It also givesrecommendations on how the conditions for energy production can be optimized inthe early zoning stage.By conducting simulations with PVsystV5.21, on three ongoing city developmentprojects in Umeå, Malmö and Stockholm and by carry out and analyzing interviewswith city planners, constructors and architects, some conclusions have been made.Several improvements, both politically, with changes in the subsidization systemand/or instatement of a new law with feed-in tariffs, and within the solar- andconstruction industry itself, with better communication between different parts of theprocess as well as better use of experience, can be made.

The aim of the project was to develop a method to investigate differences in adhesion of microorganisms to materials that contains lignocellulose. The method was tested on a gram-positive (Micrococcus lutea) and one gram-negative (E-coliJM109) bacteria.The study was begun by cultivation of the two microorganisms. The cultivation was done to calculate the generation times of the bacteria and to obtain growth curves. Cells from these cultivations were also frozen (-70ºC) and later used for inoculation.At STFI-Packforsk AB the total charge on the mass was measured and later a conductivity titration on the mass was executed as well, all to find out more about the different properties of the mass. Properties that in a later part of this study could possibly be linked to the adhesion of cells to the pulp.

The present study discusses the metabolism of ethanol in the human body from the ingestion of ethanol to the excretion of its break down products water and carbon dioxide. Ethanol is a small molecule, soluble in water as well as in organic solutions. It is quickly distributed to every section in the body, where it exerts a direct toxic effect on the cells. Ethanol cannot directly leave the body efficiently so it needs other metabolic pathways. The molecule is metabolized by oxidation, predominately in the liver.

Canine dilated cardiomyopathy (DCM) is a disease with high morbidity and mortality and with a high prevalence in certain breeds. Predominatly large breeds are affected, such as Great danes, Newfoundlands, Deerhounds and Dobermanns. One exception is Cocker spaniels, where both American and English Cocker spaniels are affected in a quite high frequency. Cardiomyopathy is characterised as a disease that affects the myocardium and gives an impaired heart function. To diagnose DCM following criteria have to be observed: 1. Dilation of the left ventricle. 2. Reduced systolic heart function. 3. Increased sphericity of the left ventricle. To be certain of the diagnosis, alternative reasons for the symptoms such as lung- and heart diseases with other etiologies have to be excluded Two different types of DCM have been found upon histological examination.