The data acquisition system COMET developed by Saab AB contains a unit for signal conditioning and A/D conversion, called KSM. The varieties in signal conditioning constitutes of a number of specific PBAs and maintenance as well as reconfiguration of these are complicated not to mention costly. This thesis has aimed to investigating whether the signal conditioning circuits can be replaced by a general purpose, programmable solution. If so, how can this be done? The development has been carried out by evaluating ideas through the use of a laboratory environment and has resulted in an analog design for laboratory purpose.