The ability to detect protein-based biomarkers, which are linked to different diseases like colorectal cancer, is very important as a diagnostic tool. Usually complex biological samples like blood are studied which will contribute to different technical issues when performing an assay. The aim with the project is to optimize and develop the high throughput protein detection technique Proximity Extension Assay, PEA, into a 96-plex panel, in hopes of discovering an expression profile for colorectal cancer. PEA was developed by Olink Bioscience and allows specific proteins in a sample to be quantitatively transformed into nucleic acid sequences that are subsequently detected and quantified with real-time PCR. Two proximity probes containing oligonucleotide sequences bind pairwise to target protein and when brought in proximity, a DNA polymerase will extend a hybridization arm from one probe over to the second forming a double-stranded DNA sequence that can serve as a template in real-time PCR.

For over 40 years, there's been a debate in Sweden of whether it's good or bad with maintenance therapy for heroin addicts. This method is far more acknowledged in other parts of Europe and in USA. The aim of this paper was to explore how public actors manifest their thoughts concerning the subject of the substitution program in Sweden. This approach includes the complex of problems that can be found in statements and the discourses that these operators stand for and support. In my analysis the philosophical thread was principally based on Michael Foucault ideas, but also on other theories related to social constructionism.

The aim of the study is to examine which present conceptions of sexuality there are in treatment of substance abuse for men. The intention is to examine how staff members in these environments perceive clients? sex and sexuality as well as studying if and in that case how they work with sexuality in treatment. A qualitative method formed the methodological approach and semistructured interviews were carried out for the collection of data. Four staff members from two different treatment institutions for substance abuse were interviewed.

ABSTRACTIn an intermediate section at a large university hospital are patients with subarachnoid hemorrhage (SAH) cared for. There are international, national and local guidelines how nutrition therapy should be implemented and how much energy each patient should be given when hospitalized. The purpose of this study was to examine the documentation and actions on nutrition in patients with SAH and to see if guidelines on nutrition were followed. The study was a quantitative, retrospective record review that was analyzed statistically and descriptive. 26 patients were included.

A water treatment unit consisting of two aeration basins, two settling tanks, a residence basinand a horizontal subsurface flow wetland were used to treat wastewater from an eggprocessing factory in Brazil. The aim of this paper was to determine the efficiency of thesystem in reducing nitrogen, phosphorus, BOD5 and TSS (among other parameters) andgetting a further understanding on different kinds of constructed treatment wetlands as well astheir nitrogen and phosphorus removal processes. The wastewater from the factory consistedof process water from manufacturing and water used for cleaning, no stormwater or sewagewater entered the system. Tests were taken three times a month from October 2013 ?til April2014.

Sahlgrenska Academyat University of GothenburgDepartment of internal medicine and clinical nutritionAbstractTitle: Can exclusive enteral nutrition replace steroid treatment in pediatric Morbus Crohn?Author: Hanna Rymark Lehnér and Josephine PetterssonSupervisor: Mette AxelsenExaminer: Anna WinkvistProgramme: Dietician study programme, 180/240 ECTSType of paper: Examination paper, 15 hpDate: May 23, 2012Background: Morbus Crohn is a chronic inflammatory bowel disease which periodically causes great suffering for the patient. There is solid scientific evidence that treatment with steroids effectively induces and preserves remission. However, side effects are many and a great risk for stunted growth and skeletal development exists in children. A widespread view is that exclusive enteral nutrition is as effective as steroids in pediatric Crohn´s.

Backgrund: Cancer är en av Sveriges och världens vanligaste folksjukdomar. När sjukdomen inte längre går att bota övergår vården från kurativ till palliativ vård. En del av patienterna i livet slutskede väljer att vårdas i hemmet och detta utgör en känslig period för både patienten och närstående. Närstående och familjemedlemmar vårdar och utför omvårdnadsuppgifter som annars skulle utföras av vårdpersonal. För att kunna utföra vården har närstående och anhörigvårdare stor behov av stöd.

Smärtlindring av cancersjuka är ett komplext och mångfacetterat område då cancer inte bara drabbar kroppen utan även själen. För att sjuksköterskan skall kunna smärtlindra patienter på ett så effektivt sätt som möjligt måste eventuella barriärer forceras genom pedagogik. Tio vetenskapliga artiklar har använts i denna litteraturstudie för att kartlägga en del av de barriärer en sjuksköterska kan stöta på i sitt pedagogiska arbete vid smärtlindring av cancersjuka, samt på vilka sätt dessa kan forceras. Resultatet visade att för att sjuksköterskan ska kunna fungera som pedagog i omvårdnaden av patienter så måste han/hon ha goda baskunskaper samt förmågan att se vilka kunskapsbehov som finns hos patienten. Resultatet visar även vikten av att patienten har god kunskap om farmakologisk smärtlindring..

Bakgrund: Varje år drabbas cirka 8000 kvinnor av bröstcancer och är därmed den vanligast förekommande cancerformen hos kvinnor. Den främsta behandlingsformen är kirurgi där man vanligtvis väljer att utföra en mastektomi, där hela bröstet opereras bort, eller bröstbevarande kirurgi. Förlusten av ett eller båda brösten ger ofta fysiska och psykiska konsekvenser. Syfte: Syftet med denna studie var att beskriva kvinnors upplevelser av sin hälsorelaterade livskvalitet och psykosociala hälsa efter mastektomi med eller utan rekonstruktion. Metod: En deskriptiv studie med kvalitativ metod användes.

In Sweden has the temporary agency work industry settled in an explosive way since the deregulation of the unemployment agency monopole in 1993. The demand of civil right for the employer that is rented out confronts the entire labour law regulation with new challenges.The purpose with this paper is an investigation of the principle of equal treatment in The Swedish temporary agency work act and also to create a deeper understanding of the effects of labour and employment relationship. An investigation of relevant collective agreements will be done to highlight the difficulties the principal of equal treatment is exposed to. Further on is there a will to gain understanding for the wage concept and what possible can be included in the wage concept in relation to the principal of equal treatment in The temporary agency work directive. By using the dogmatic method, an approach to descriptive identifying relevant sources of law and clarify the legal situation in the area.In the conclusions it will be determined that the principle of equal treatment in The Swedish temporary agency work act have different effects depending on if the temporary agency or if the client corporation is tied to an collective agreement alternative if a collective agreement is completely missing.

Water logistics has long been a problem in order to effectively carry out stump treatment in both thinning and final felling. It is important that the stump treatment? equipment is configured as well as a sufficient amount of water is carried out on the harvester to get a cost? effective treatment. The flow control of the equipment has improved and water can be dispensed more efficient, but still the amount of water on the machine is a crucial factor in the total cost estimate. The knowledge of the tools available to bring water as well as the internal logistics of loading and transport to the felling site is deficient. Increased focus on "smart" solutions to manage water cost is of great importance in order to combat Hetrobasidion spp in both thinning and final felling. The purpose of the study is to describe and summarize different solutions of water logistics at stump treatment in final felling.

BackgroundWhen women have breast pain this usually is not associated with myocardial infarction, which results in that they get less attention and wrong treatment. The nurse has an important role in informing and educating patients and families during hospitalization, which is usually short. Continuous training, written information and repetition for patient and family throughout the hospital stay are of considerable importance to clarify that the patient understands and to reduce the anxiety of being discharged.AimThe aim is to describe nurses' experiences of caring for older women with myocardial infarction.MethodsA qualitative method was used. The collection of data was done by six interviews with nurses in geriatric care and elderly care. Dataset has been processed based on a content analysis and divided into subcategories and main categories using meaningful units.ResultsNot having knowledge of older women with myocardial infarction was expressed as frustrating and nurses described how they were afraid to ask their colleagues.

The euthropthication of the Baltic Sea is a threat that is beginning to be taken seriously by the governments concerned. In Sweden, regulations concerning the allowed nitrogen (N) concentration in the effluent water from wastewater treatment plants are being tightened up. The Rimbo wastewater treatment plant has been imposed to reduce the annual mean concentration of total N in the effluent water to levels below 15 mg l-1. A more and more common way to reduce the nitrogen level in wastewater is to let the water pass through a wetland. This study investigates the possibility to build this kind of wetland at the outlet of the Rimbo wastewater treatment plant.A prestudy of the topography, soil characteristics and groundwater flow indicates that the land area in question is well suited for the construction of a wetland.

Varje år drabbas ungefär 50 000 personer i Sverige av cancer. Detta innebär att en halv miljon svenskar om året har en nära anhörig som drabbas. Cancersjukdomens inverkan på de närståendes liv är påtaglig. Förutom att bemöta och ta hand om patienten ska sjuksköterskan även uppmärksamma de närståendes upplevelser och behov. Syftet med denna studie var att beskriva närståendes upplevelser av att leva nära en anhörig som drabbats av cancer.

Young men who commit sexual abuse is a complex topic. This study is based on litterature on the subject and the material is processed through a qualitative content analysis. The study aims to study how the litterature describes the reasons why young men commit sexual abuse. It also aims to explore what is described to be effective treatment of young men who committed sexual abuse. The study found that most of the young men who commit sexual abuse comes from families where violence and psycohological abuse occurs. Many have themselves been victims of sexual abuse.