This master thesis comprises analysis and dimensioning of a keyed joint between a generator axis and a hub with aid from the FEM-software ANSYS Workbench 13.0.The generator axis is a part of a hydroelectric power station that generates electricity with a reactions turbine, a Kaplan turbine. The existing keyway consists of one parallel key with the width 90 mm and height 45 mm. Due to a planned increase of the power of the generated power with 32 % a design study was needed to see if the keyed joint would be suitable for the extra force. Because of the fact that the axis diameter is bigger than the standards covers/recommends a the keyway had to be re-dimensioned. In an earlier assignment from Skellefteå Kraft AB to Sweco Energuide the keyway was planned to be properly dimensioned, but no final solution was approved.During this master thesis a number of different numerical tests were made.

Platelets are important for the healing of damaged blood vessels since they have an importantpart to play in the coagulation process. At the same time, the blood must be kept fluid and notcoagulate at the wrong time. Therefore there are factors that effect the aggregation of plateletsin a positive or a negative way.Previous investigations have shown that platelets during stirring conditions produce reactiveoxygen species (ROS) that weaken the inhibiting effect of nitric oxides (NO) on platelets andthat the drug Dexamethasone (Dex) can reduce the ROS-production.The aim of this project was to investigate if glucocorticoids, in this case Dexamethasone,could restore the inhibiting effect of NO on platelets and if there was any decrease in ROS-production.The result of the ROS-measurements showed a great variance and it was difficult to draw anyconclusions from them, but a clear decrease in ROS, as previous reported, was not shown. In the aggregation experiments the inhibiting effect of NO was observed through the drug S-nitroso-N-acetylpenicillamine (SNAP), a NO-donator.From the aggregation experiments, the result seemed to be that SNAP during longerincubation time lost its inhibiting effect, probably because the cells become desensitized.With superoxid dismutase (SOD), the effect of SNAP increased, both in the experiment withlonger and shorter incubation times. Dex seemed to reinforce the aggregation in relation toboth SOD and SNAP.

Investors? use borrowing as a way to profit from leverage advantages in their portfolios.When investors borrow with their securities as safety for the loan and the value of thesecurities decrease the investor can get a portfolio with more credit than what is covered bythe value of the securities and risk huge losses. To what extent an investor is allowed toborrow with his portfolio as safety depends on the bank or broker and varies between theproviders. By studying available material and in addition to that making an empirical study Iattempt to find out the reason for the varying degrees of leverage possibilities between thebrokers and how the degree of maximum borrowing on the securities are decided. Thefindings show that decision of leverage degree on a security is made after first making aquantitative analysis of the stocks volatility and liquidity and thereafter make a qualitativeanalysis of the company.

Staphylococcus aureus is the most clinically important Staphylococcus species and is associated with high mortality in patients with positive blood cultures. S. aureus bacteria may cause a variety of disease manifestations ranging from minor skin infections to life-threatening conditions such as pneumonia, meningitis, osteomyelitis, endocarditis, toxic shock syndrome (TSS) and sepsis. This microorganism belonging to the gram positive cocci may also be part of the normal flora. In Sweden, penicillinase-stable penicillins are the primary alternatives to treat S.

Inledning: Sjukvården är beroende av frivilliga bloddonatorer. Det behövs alltid fler bloddonatorer då vi med dagens sjukvård kan utföra alltmer avancerad kirurgi samt rädda och hjälpa allt fler sjuka samt skadade, med hjälp av blod från frivilliga donatorer.Syfte: Syftet var att undersöka vilka skäl som anges till att inte donera blod, samt undersöka om viljan att ge blod skiljer sig beroende på kön, ålder och om man har yrkes- eller studieanknytning till sjukvård. Syftet var också att undersöka vilka faktorer potentiella blodgivare anger som motiverande till att donera blod.Metod: Denna uppsats baseras på en kvantitativ tvärsnittsstudie, bestående av en webbenkät som delats av författarnas på det sociala mediet Facebook. Enkäten vände sig till personer som enligt blodcentralens kriterier får donera blod, totalt inkom 90 svar, med ett bortfall på totalt 11 personer. Enkäter analyserades sedan kvantitativt med hjälp av statistikprogrammet SPSS.Resultat: Studien visar att den vanligaste orsaken till att respondenten inte gått och donerat blod är att de tillfrågade har tänkt på det men att det inte blivit av.

Studies have shown that stress is common in the nursing profession.Purpose: The aim was to investigate nurses' experience of stress in the work environment at the University Hospital in Uppsala and how nurses deal with this stress and whether the perceived stress experienced affect patient safety and in what way. Method: The study had a descriptive, qualitative design based on nine interviews. The selection criteria for the study was that participants were nurses and that they had worked at least one year within the profession and that they had experienced stress in their work environment. Data from the interviews was analyzed using the qualitative content analysis method by Graneheim and Lundman. Results: The analysis resulted in three categories: "Stress in the workplace?, "stress management" and "patient safety? and showed that all participants had experienced stress repeatedly in their workplaces.

What affect if an incident is reported?- an interview study with nursesABSTRACTEveryday in health care, there are incidents which can harm patients. However, reporting these incidents is not always a positive experience. The number of incident reports which are documented are a lot fewer than the number of incidents that actually occur. The purpose of the present study was to describe factors that affect nurses? decisions on whether to report an incident or not.

Passagerarna behöver mera tid än säkerhetsinformation eftersom passagerarna har så bråttom att komma ombord, boka bord och handla tax-free. Därmed missar passagerarna viktig säkerhetsinformation som alltid ges vid avgång via fartygets högtalarsystem. Det finns klar och tydlig säkerhetsinformation ombord. Det viktiga är sättet att ge information än att ge mera information. Idag informeras passagerarna via videoskärmar, utrymningskartor på hyttdörrar, via högtalarsystemet ombord, säkerhetsbroschyrer i hytter och information, välutbildad besättning och det är väl skyltat ombord.

Report of diploma work conducted at the Swedish Radiation Safety Authority (SSM) as part of the bachelors program in Nuclear Engineering at Uppsala University.All nuclear power plants in Sweden are obliged to report any deficiency in their barriers or the defense in depth in obedience to SSM?s regulations concerning safety in nuclear facilities. In addition, there is an international system for reporting such events. The purpose of this thesis is to study the Swedish report system and to analyze the differences between Swedish and international event reporting.In the Swedish system, SSM?s regulations are effectuated by means of event reports classified as category 1-3, designed individually at each Swedish facility.

What affect if an incident is reported?- an interview study with nursesABSTRACTEveryday in health care, there are incidents which can harm patients. However, reporting these incidents is not always a positive experience. The number of incident reports which are documented are a lot fewer than the number of incidents that actually occur. The purpose of the present study was to describe factors that affect nurses? decisions on whether to report an incident or not.

Pyometra, chronic purulent metritis in metoestrus, is a common disease in intact bitches. About 25% of all bitches in Sweden have contracted the disease before ten years of age. Clinical signs of the disease are varied, and the course may be either slow or acute. The diagnosis is most commonly made by radiographical or ultrasonographical examination of the abdomen in combination with blood biochemical and hematological analyses. The safest and most efficient treatment of pyometra is surgical ovariohysterectomy.There is room for improvement of both diagnostic tools and possible prognostic indicators for pyometra.Mast cells are large leucocytes, with granule that contain inflammatory mediators.

The purpose with this study was to investigate how the behaviour and physiological parameters differ between high ranked and low ranked cows, and between cows in an automatic milking system verses conventional milking parlour. The study was carried out at the Kungsängen research Centre, Department of animal nutrition an management, Swedish University of Agriculture Sciences, Uppsala. Twelve cows, the six highest and the six lowest in social rank were selected from the automatic milking system for the experiment. Ten cows, the five highest and five lowest in social rank were selected from the conventional system. Blood samples were taken during milking and resting.

Cardiovascular disease is the leading cause of death in the Western world. For persons who have had a myocardial infarction the following rehabilitation and the group training, which is a part of this, are very important. The cardiac rehabilitation is designed to limit the physiological and psychological effects of cardiovascular disease. Purpose: This study aimed to examine how patients with cardiovascular disease experienced group training in relation to the International Classification of Function, Disability and Health, ICF. Method: A qualitative interview study was performed according to Malterud, inspired by the Grounded Theory method.

Staphylococcus aureus is the most clinically important Staphylococcus species and is associated with high mortality in patients with positive blood cultures. S. aureus bacteria may cause a variety of disease manifestations ranging from minor skin infections to life-threatening conditions such as pneumonia, meningitis, osteomyelitis, endocarditis, toxic shock syndrome (TSS) and sepsis. This microorganism belonging to the gram positive cocci may also be part of the normal flora. In Sweden, penicillinase-stable penicillins are the primary alternatives to treat S.

The calcium homeostasis in the body is normally strict regulated to be kept within very narrow limits. This regulation is due to the action of parathyroid hormone (PTH) which is synthesized in the chief cells of the parathyroid glands. In different diseases, the calcium homeostasis is disturbed and this could either be due to a dysfunction of the parathyroid gland itself, or it could have a completely different explanation. To investigate disturbed calciumhomeostasis, ionized calcium and PTH can be analyzed from a blood sample. There are a lot of different assays to measure PTH in humans.