Methadone is frequently used as an analgesic drug for dogs although there are very few studies describing the pharmacokinetics of methadone in this species. In man methadone has a long half-life and there are considerable differences in pharmacokinetics between individuals. The dose interval is lengthened when the drug is used fore longer periods of time due to prolonged half-life. Therefore the drug dose must be adjusted individually. The purpose of this study was to study the fundamental pharmacokinetics of methadone in dogs, and to find an optimal drug dosage.

Bakgrund: De människor som personalen möter inom vården har på ett eller annat sätt drabbats av sjukdom eller skada, fysisk eller psykisk. Sjuksköterskans uppgift är att främja hälsa och lindra lidande. Det kan sjuksköterskan göra genom att använda humor som kan lätta upp patientens tillvaro i en svår livssituation. Syfte: Syftet med denna litteraturstudie var att belysa vad humor har för inverkan på patienten och om den kan vara till nytta i omvårdnadsarbetet. Metod: Resultatet i litteraturstudien baseras på sjutton stycken vetenskapliga artiklar som söktes i databaser som var relevanta utifrån syftet.

Sahlgrenska Academyat University of GothenburgDepartment of internal medicine and clinical nutritionAbstractTitle: Does omega-3 mitigate skin symptoms in psoriatic patients? ? A systematic review about the effects of supplementationAuthor: Anita Borgmästars and Sara LinderSupervisor: Mette AxelsenExaminer: Anna WinkvistProgramme: Dietician study programme, 180/240 ECTSType of paper: Examination paper, 15 hpDate: May 22, 2012Background: Psoriasis is an inflammatory skin disease with high prevalency. Its treatment is time-consuming and associated with many side effects. Therefore alternative forms of treatment, among them omega-3 supplementation, have been investigated. Omega-3 is a family of polyunsaturated fatty acids whose metabolites participate in the regulation of inflammatory reactions in tissues and may therefore have a positive effect on skin symptoms in patients with psoriasis.Objective: To determine if omega-3 supplementation has a beneficial effect on skin symptoms in psoriasis compared to omega-6 supplementation by rating the evidence quality in available studies.Search strategy: The literature search was conducted in the databases PubMed, Scopus and Amed.

Superior Canal Dehiscence Syndrome (SCDS) is a newly described syndrome with symptoms including sound- and pressure induced vertigo, conductive hyperacusis and autophony. SCDS is caused by absence of bone overlying the superior semicircular canal and can be surgically treated. As the syndrome and surgical technique is new, it is of importance to study possible postoperative outcomes..

The aim of the project was to study the effect of oral administration of glucose and leucin on the resynthesis of muscle glycogen after intense exercise in Standardbred trotters. In a crossover design, 11 Standardbred trotters performed a standardized exercise test on two occasions in order to deplete muscle glycogen. The exercise test comprised a warm up period, 7 repeated bouts of exercise on an uphill 500 m slope, and a recovery period. After the exercise test horses received: 1) a solution of glucose and leucine via a nasogastric tube at 0 minutes and at 240 minutes post exercise and a single bout of glucose at 120 minutes post exercise or 2) water (placebo) at 0, 120 and 240 minutes. Blood samples for measurement of glucose and insulin concentrations were collected at rest, when the horses returned to the stables directly after exercise and throughout the 6 hour recovery phase. During the first recovery hour, samples were collected every 15 minutes and then every 30 minutes over the next 5 hours.

Syftet med litteraturstudien var att undersöka förekomsten av karies och parodontit hos personer med Morbus Crohn. Metoden som användes var en allmän litteraturstudie. Materialet till litteraturstudien samlades in genom sökning i databaserna Cinahl, PubMed och ScienceDirect. De sökord som användes vid litteratursökningen i samtliga databaser var ?caries?, ?Crohn?s disease?, ?periodontal disease? och ?periodontitis?.

The purpose of this study is to extend the understanding of how professionals in modern organisations want to be managed. We especially investigate professionals changing industries to describe if, and how, aprofessional in this situation is becoming a professional again after the change. This to find connections between intrinsic motivation and attitudes towards professionalism on one side, and applicable managerial methodson the other. Best practice in managing professionals is traditionally considered to be non-invasive methodologies such as indoctrination and training. Beyond that, operational-level management is usually considered to be bound to fail.The analysis suggests the following:? A professional changing industry will become professional again.? The driving force for becoming professional again is the strive for horisontal specialization, induced by higher education.? Management of professionals needs to account for the integrity of the horizontal specialization of the professional.

The incidence of damage to the claws and legs in piglets caused by the floor in farrowing pens is a widely known problem and very common in today's pig herds. Although the association between floor and damage has been known for over 35 years, no suitable solution has been found to reduce the negative impact. The purpose of this study was to make a literature study to document the experiences of the use of different types of flooring in farrowing pens and also, in an own study, examine if soft floor in farrowing crates could lead to reduced damage to the claws and legs in piglets compared to concrete floor. The study was conducted in two herds, A and B. In each herd, farrowing pens with concrete floor and concrete floor with polyurethane coating were compared.

Introduktion: Invandringen ökar konstant till Sverige och att vara född utanför Norden anses vara den största riskfaktorn för försämrad tandhälsa. Flera orala sjukdomar är en konsekvens av bristande munhygien, bakteriella beläggningar och tobaksbruk.Syfte: Syftet med studien var att kartlägga upplevelsen av den egna munhälsan, kunskapen om munhälsa, munhygienvanor samt tobaksvanor hos en grupp invandrare.Frågeställningar: Vilka är dessa personers munhygienvanor? Vilka är dessa personers tobaksvanor? Vilken kunskap har dessa personer vad gäller sjukdomsuppkomst och prevention beträffande karies, gingivit och parodontit? Hur upplever dessa personer sin individuella munhälsa?Metod: En enkätundersökning genomfördes på en skola i Stockholm som undervisar i svenska för invandrare (SFI). Totalt deltog 56 individer i undersökningen.Resultat: Resultatet visade en varierande kunskapsnivå gällande orala sjukdomars uppkomst och prevention. Beträffande munhygienvanor uppger 48,1 % att de borstar tänderna två gånger dagligen och 80,8 % använder tandkräm innehållande fluor.

Syfte: Syftet med denna studie var att beskriva uppfattningen hos sjuksköterskor med tjänst på särskilda boenden gällande deras arbete med tillämpningen av munhälsobedömningar och deras uppfattning om hur munvård utförs. Metod: Studien genomfördes med kvalitativ deskriptiv design. Data samlades in hjälp av intervjuer med sjuksköterskor (n= 6).  Intervjuerna analyserades med hjälp av innehållsanalys och fyra olika teman identifierades: Sjuksköterskors uppfattning om munvård, sjuksköterskors uppfattning om munhälsobedömning, sjuksköterskors uppfattning om munvår och munhälsobedömning i samband med palliativ vård samt sjuksköterskor uppfattning om samarbete med folktandvården. Resultat: Resultatet visade sjuksköterskorna uppfattade att munhälsobedömningar sällan utförs av sjuksköterskorna.

Syftet med denna studie är att undersöka hur en grupp typiskt utvecklade, svenska barn, i åldrarna fyra till tio år presterar på tre deltest i VMPAC, för att därmed skapa ett underlag för en referens för svenska barn i bedömningen av avvikande utveckling. Studiens frågeställningar är: 1. Hur presterar en grupp typiskt utvecklade, svenska barn, i åldrarna fyra till tio år, på tre deltest i VMPAC (Focal Oromotor Control, Sequencing Maintenance Control och Connected Speech and Language Control)? och 2. Förekommer det några skillnader mellan en grupp typiskt utvecklade, svenska barn, jämfört med den amerikanska normeringen i VMPAC och barn med verbal dyspraxi (CAS) undersökta inom ramen för en magisteruppsats (Björelius-Hort, 2009)? Oral- och talmotorisk förmåga hos 23 svenska barn i åldrarna fyra till tio år, som åldersmatchats mot barn med verbal dyspraxi (Björelius-Hort, 2009), testades med deltest två, tre och fyra ur VMPAC.

This thesis describes teh solution of two problems regarding safety on powered lawnmowers; protectning the users from injury when using the lawnmower in slopes, and when cleaning the cutting blade.The task was carried out through initial studies on a representative lawnmower. A generation of ideas followed with an evaluation to select the best solution. The winning concept was further developed to reach acceptable performance. The word resulted in a functioning prototype utilising an original way of detecting inclinations without incorrect signals. It c an serve as a platform for further development into a product.The work gives insightful experience of solving real-world problems, and especially to deal with situations where several variables and their effects are unknownPlease note that several parts of the work are confidential, and have therefore been removed from the thesis..

Handling of animals during anaesthesia is an important field in the profession as a veterinary nurse and in which intubation is an essential part. Hence, adequate knowledge is necessary for the welfare of the animal. The objective of this literature study was to make it useful and trustworthy for veterinary nurses. It is intended to describe and summarize existing scientificity with its benefits and disadvantages within the different areas of intubation techniques and alternative methods of inhalation anaesthetic supplementation for general anaesthesia in rabbits. Endotracheal intubation in rabbits can be complicated and technically demanding due to the anatomy of the oropharynx including the narrowness of this structure, a relatively large tongue, large incisors and a limited mobility of the temperomandibular joint. The obstructed visualization of larynx and the rabbit?s tendency to develop laryngospasm contributes to the difficulty of intubation. Rabbits are susceptible to tracheal injury and multiple intubation attempts can cause tracheal lesions due to repeated damage to the tracheal mucous membrane, although damage can occur after a single intubation attempt as well. An ETT (endotracheal tube) with or without a cuff can be used during orotracheal intubation in rabbits.

This thesis has been carried out in collaboration with two students at the Department of Dental Medicine at Karolinska Institutet in Stockholm, Sweden. The aim of this project was to construct a computerized decision support system to facilitate diagnosis of changes in the Oral Mucosa using information collected by the above mentioned students. A program which poses specic questions to the user was constructed with the Java programming language. Depending on how these questions were answered, one or more possible diagnoses were presented by the program. In order to conclude whether or not this program was of any use in terms of time savings, a series of tests were run and timed both when using the program and when not.

I de fall enskilda aktieägare tillfogas skada, genom organledamots handlande, innehar dessa rättigheten att påkalla skadeståndsansvar enligt 29:1 1 st. 2 men. ABL. I den svenska rättstillämpningen ter sig dock tillämpningen av paragrafen, i samband med indirekta skador, problematisk. Problematiken hänför sig till vilka regler, vars åsidosättande, aktualiserar tillämpningen av paragrafen tillsammans med aktieägares talerätt.Två tolkningar kan i fallet identifieras, vilka framförts inom doktrinen, varvid en begränsad och en mer liberal.