Diabetes mellitus is a rising epidemic throughout the world and there is currently great interest in quantifying the beta-cell mass (BCM) in vivo non-invasively. In the present experiment, the feasibility of in vivo imaging of the glucagon-like peptide-1 receptor (GLP-1R) in beta-cells was examined, using the positron emission tomography (PET) tracer [68Ga]Ga-DO3A-VS-Cys40-exendin-4 as a marker, in native pancreatic beta-cells of a porcine diabetic animal model and healthy controls. Eight Swedish high-health domestic pigs were randomly assigned to be either controls or made diabetic using streptozotocin (STZ). The experiment proceeded during eight weeks, starting with an acclimatisation period. Once the pigs had been socialised they underwent surgery for the insertion of a jugular vein catheter, allowing induction of diabetes with STZ, intravenous (i.v.) injections and stress-free blood sampling. Development of diabetes was confirmed by clinical examinations, blood glucose values and insulin-staining of pancreatic sections post mortem. The diabetic pigs were insulin treated and responded well.

Opioids are considered the "golden standard" in pain management for both humans and small animals, but is used less often in equine medicine - probably for fear of side effects. Are there any studies that suggest that side effects are a major problem, or is it lack of experience which is the greatest obstacle to use? As early as 1937 it was shown that morphine and morphine derivatives provide analgesia in horses. For species other than horses used opioids often both pre-, intra-and postoperatively. They relieve pain effectively and are often included in the anesthesia protocol.

The object of investigation in this essay is the epic novel sequence Jernbanan written by Sara Lidman. More specifically the investigation takes on the idea of a ?sam-vett? as it is formulated in Jernbanan. The ?sam-vett? is an idea about the undivided unity of man, nature and animal, and with a kind of primitive trait.

The purpose of this essay is to examine the approach of the EU towards the reform efforts of Turkey and Bosnia and Herzegovina in the countries ambitions for EU memberships. The question formulation of the essay is whether there is differences in Turkey?s and Bosnia and Herzegovina?s qualifications for an EU-membership from an EU perspective. In order to better answer the question, we use two part questions. One is about the criterias and qualifications that need to be met in order to get a membership.

The purpose of this essay is to outline the aspects of the rule of law that can be applied to credibility assessment in the asylum procedure, and more specifically what factors influence the assessment of credibility in practice. To evaluate this procedure, a multidisciplinary method has been used. Secondary data has been collected from previous academic research and from legal documents such as the Swedish Aliens Act. Since the area of study lacks a reflection on how credibility issues are dealt with in practice, primary research in the form of qualitative interviews has been conducted.Key findings suggest that the Swedish asylum system does offer a fairly inclusive refugee law and rights protection relating to the rule of law. However, the study also suggests that the decision maker's own subjectivity, lack of training relating to trauma and torture victims as well as a rigid system of regulations contribute to credibility assessments being arbitrary and discretionary, in violation of the rule of law..

Infection with the bovine lungworm - Dictyocaulus viviparus - is occasionally a problem in Swedish cattle herds. The infection could act in synergism with other infections such as Corona virus to create a poorer welfare and productivity in cattle. Studies have shown that a diagnosis can be made with both the Baermann method and with an ELISA. In Norway diagnosis of BVDV on a herd level is attained through pooled serum samples. The question was raised whether pooled serum samples could be used in a similar fashion to attain status on a herd level for lungworm.

Syftet med denna studie är att undersöka hur musiker ser på begrepp som ljudnivå, musikupplevelse och relationen mellan dessa. Underlaget för studien är sex intervjuer med musiker och ljudtekniker, med och utan hörselskador. Studien byggs på sex kvalitativa intervjuer och är avgränsad till att i första hand behandla detta inom musikstilar vilka är baserade på trummor och bas ? pop/rock, jazz/blues.Studiens resultat visar att parametrar som t.ex. genre, lokal, ljudteknik, ljudtekniker och arrangör har inverkan på det ljud och den ljudnivå som uppnås vid en konsert.Vidare redovisas respondenternas syn på relationen mellan ljudnivåer och musikupplevelse.

Petro-electric IFVs (Infantry fighting vehicles) or hybrid-IFV?s are not a new phenomenon. During the 1900?s Germany as well as the U.S both tested vehicles constructed with hybrid technology. In spite of several identified advantages, no serving hybrid-IFV exists today.

This master thesis deals with questions concerning facts and fiction in the world of Beatrix Potter's rabbits. The purpose is first and foremost to find the connections between the pet rabbits, that she used as art models, and the rabbits that came to life through her "tales".The method has been to gather facts through biographic reading, and to analyse Beatrix Potter's rabbit tales, using tools developed by Swedish picture book experts. The rabbit characters are thoroughly examined and so are the settings where the tales take place. Matters concerning Beatrix Potter's painting technique and illustration style as well as her literary and pictorial inspirations are dealt with.Conclusions are, that the fictive rabbit characters have indeed a lot to do with the fact that Beatrix Potter was interested in natural history and studied animal behaviour and anatomy in detail. For a long time rabbits, both wild and domesticated, were her favourite study objects which provided conditions for her rabbit fantasies.

I denna studie undersöker jag barn i förskolan mellan fyra och fem år. Vad de har för tankar i ett möte med för dem ett okänt djur, vattenloppan. Aktiviteten där jag även ställt frågor till barnen angående bl.a. vattenloppans utseende och livsmiljö. Samtidigt som jag filmat har jag kunnat observera två grupper som möter dessa djur antingen med hjälp av bild och video eller med verkliga djur.

The purpose of the research is to find out how the teacher of the pre-school looks at the value of the nature Pre-school. To get an understanding of what the nature pre-school enviorment can bring, we are talking about learning, knowledge, and experience combined with the everyday lessons learned from the natural world. The research is a stepping stone on the pre-school teacher?s thoughts and reflections of what a nature pre-school is. This is grounded in a view of how having options for alternative schools lead to wider research, and all conclusions where formed after multiple interviews and analysis.The results showed that the teachers involved are very positive to the nature pre-school environment and learning process.

Innovation has been identified as one of the key factors for economic growth long ago. However, the emergence of ?knowledge century? further strengthened the role of the concept since proper management of the knowledge is essential to make the best out of the innovative capacity of the companies as well as the countries. This necessitates a balanced intellectual property rights (IPR) systems, since these rights provide the basis to solve the market failures faced by innovating firms by creating property rights over knowledge. There is an inherent dilemma between invention and diffusion.

The purpose of this study was to do a narrative survey of the discussion about violence in partner relationships that is held in research literature. The question at issue was: How do research literature discuss violence in partner relationships, with focus on heterosexual relationships? The eight primary documents that have been chosen are written by researchers, professional therapists, National Counsil for Women's protection (Nationellt Råd för Kvinnofrid, NRK) and Swedish Government Official Report (Statens Offentliga Utredningar, SOU). To investigate the theories, discover the similarities and differences between them and how they can complement each other, the documents statements has been analyzed with a dialectic-hermeneutic approach and social constructionism and discourse theory.The research findings showed that the gender perspective theory, the psychodynamic theory and the social psychology theory have a few things in common, but that they on the whole are different and contradict each other. The gender perspective theory dominates the discussion but needs to be combined with the other theories to give a more all-embracing understanding.

Instrumental conditioning, the use of reinforcement and punishment, is used when training horses and these procedures may have different consequences regarding animal welfare. The aim of this study was to investigate what kind of reinforcers that are used in training horses and when these reinforcers are used. This study has its focus on positive reinforcement and its advantages and disadvantages. Interviews of five A-level and B -level equestrian coaches about their training methods were conducted to complement the literature search and give a greater understanding to why certain methods are used or not in training horses. The results show that negative reinforcement seems to be the foundation of training horses whereas positive reinforcement is used but not to the same extent.

Pets like dogs and cats have a considerable importance for humans and research demonstrate a variety of positive economic and social effects in society due to our pet companions. The presences of pets are increasing on a global scale with correlation to economic development in low- and middle income countries. For example dogs have doubled in India over a five year period. The feed industry for dogs and cats is also the fastest growing sector in the food industry and certain pets have a significant animal protein intake which, depending on the choice of resources may provide a high ecological footprint. Examples of environmental effects with distribution and manufacturing of pet food are increased greenhouse gas emissions, waste, use of water and energy.