This literature study aims to examine the existence of cancer stem cells in breast cancer. The cancer stem cell theory states that there is a hierarchical organization within a tumour, in which a small subpopulation of the cells can initiate new tumours and maintain tumour growth whilst the bulk of the tumour cannot. These tumour initiating cells have shown to possess many characteristics similar to those of adult stem cells, which is why they are often referred to as cancer stem cells. Both cell types have the capacity of asymmetric division and have shown to possess mechanisms of resistance to both apoptosis and cancer drugs. The cancer stem cell theory elucidates many biological aspects such as the heterogeneity of tumours and the relapse of many cancers after what appeared to be successful treatments.

Propofol is an intravenously administered, hypnotic and short- acting pharmaceutical. One common sideeffect (>1:10) and therefore a disadvantage with propofol is the local pain that arise when the initial injection is given. Why the pain arise is not clearly understood. A majority of different pharmacological treatments, different doses and combinations, alternative administrations methods and physical interventions have been tried to reduce the pain when injection of propofol is given. One important task for the nurse is to relieve pain for patients.

The purpose of this paper was to examine how clients on the unit for adults at Södemalms district administration (Stockholm, Sweden) with severe mental illness and substance abuse differs from other clients with substance abuse at the baseline and at follow-up one year later. We have used a quantitative method and analyzed material from ASI-interviews performed at the adult drug abuse unit at Södermalm during the time period 2002-2010. At the baseline the clients with substance abuse and co-occurring severe mental illness have more problems than other clients, primarily in the area of mental health. They spend more time alone and are more likely to engage in illegal activities. Interviewers assess their situation as more serious and that they need more help in all of ASI's areas of life than other clients.

BackgroundResearch shows that the majority of patients feel anxiety before and during anesthesia. It has been shown in several studies that preoperative anxiety may cause adverse effects in the postoperative course. Nurse anesthetists have a key role in creating a safe environment and the opportunity to use different interventions to reduce the degree of anxiety.AimThe aim of the study was to examine which interventions may reduce anxiety in adult patients before and during both general, local and regional anesthesia.DesignSystematic literature review with a quantitative approach.ResultsSeveral studies indicate that gabapentin and pregabalin can reduce anxiety before and during anesthesia. The anxiety reducing effect appeared to be dose dependent. The naturopathic drugs Citrus aurantium blossom and Passiflora incarnata Linneaus were found to reduce anxiety before anesthesia.

The aim of this study was to examine young adult cannabis users? attitudes towards cannabis and their perception of the normalization of cannabis. The purpose was also to explore how their views of cannabis correspond with norms regarding cannabis. This study is based on interviews with five young adult cannabis users. The theoretical framework is based on Parker?s normalization thesis, Goffman?s notion of stigma, Becker?s definition of outsiders and the definition of social identity developed by Stone.

In Sweden approximately ten percent of all children grows up in a family where at least one parent is having an alcohol related addiction. Since 1998 the development of group activities for children in this situation has been immense. The aim of group activities is to break the child's isolation and make them feel that they are not lonely in their experiences, give them knowledge about addiction and relive the pressure of guilt and responsibility.In a comparative study we examined studied how two different group activity models one with the conception of illness and one without, use the children's network to support the group process. The aim was also to find each models definition of the "normal family", since we understood the groupactivity as a part in the normalization process. We reached our aim through interviews with group leaders and by literature studies.

The aim of the study has been to find out children?s librarians? views on and management of media that contains topics with a controversial nature and also to find out how this affects the public library as a democratic institution. We have conducted the study by interviewing six children?s librarians. By using Vestheim?s terms value rationality and instrumental rationality, we have been categorizing the answers from our informants and thus identified two different points of view.

Pastern dermatitis is a common condition among horses. It is a symptom, a reaction in the skin of the pastern rather than a diagnose. There are a lot of homemade treatments when you ask horse owners how they handle pastern dermatitis, but what does the science say about how it should be treated? Today there is a growing problem with antibiotic resistance, but how good are the veterinarians on testing for resistance before they describe antibiotics? Bacteria and fungus is seldom the primary cause for pastern dermatitis, the reaction is often secondary to environmental factors. It?s difficult to diagnose the primary factor and it´s even more difficult when the horse has been treated in different ways before the veterinarian gets involved.

The purpose of this study was to evaluate enantioselective analytical methods by separation of the enantiomers of four drugs (citalopram, zopiclone, tramadol and methylphenidate) and their metabolites. The analyses were performed with HPLC-UV with columns whose stationary phases were based on macrocyclic glycopeptides (Chirobiotic V, V2 and T) and polysaccharides (Lux Cellulose-1, Cellulose-2 and Amylose-2).The Chirobiotic V column showed high selectivity for citalopram and its metabolites. High resolution was obtained using a mobile phase consisting of methanol, acetic acid and ammonia. High selectivity for the enantiomers of zopiclone and its metabolites were obtained on the Cellulose-2 column using a mobile phase consisting of acetonitrile and ammonium acetate buffer.The enantiomers of tramadol were separated with the Amylose-2 column. However, changes in the pressure arose, probably caused by the additive NH4HCO3.

Alkoholmissbruk kan orsaka sociala och ekonomiska konsekvenser för familjer och resten av samhället. Arbetsplatsen som arena är viktig för folkhälsoarbete. Där finns möjligheten att fånga upp och påverka människor, som visar sig ha ett riskbeteende när det gäller alkoholkonsumtion. Mellan åren 1996 och 2004 ökade den totala alkoholkonsumtionen i Sverige när det gäller ren alkohol. Sedan avskaffandet av införselkvoterna har konsumtionen i landet fram till år 2010 successivt minskat.

?Medicines are available in different forms and often have different types of compound components. More and more drugs are found on the market. This means that professionals who handle different medicines must have access to more and more information.The information available includes information about side effects, active substances, interactions and pill identification. You may want to access different information, depending on your profession.

En lyckad social tillställning är beroende av gästernas humör. Värden har vissa verktyg hen kan ta till hjälp för att behålla en god atmosfär. I följande uppsats diskuterades möjligheterna alkoholen ger i jakten på ett framgångsrikt värdskap. Syftet med studien är att belysa alkohol som socialt verktyg vid mötet mellan värd och gäst med avseende att skapa ett lyckat värdskap.Uppsatsen är en litteraturstudie som har använt sig av fem vetenskapliga artiklar för besvara syftet. Resultatet som artiklarna visade var att alkohol i måttliga mängder gör människor mer sociala och avslappnade.

The aim of this study is to highlight drug experiences and the significance our interviewee?s ascribe to their drug experiences in conjunction to their everyday lives. In the concluding chapter of this study we have used the collective experiences of the participants to allow us to engage in a dialogue of why it is important to acknowledge the attributes and needs an individual attaches to his/her perspective drug in the field of social welfare in Sweden. Symbolic Interactionism as a theoretical approach is used as the framework for understanding responses of participants in this study. The word ?experience? is a comprehensive concept for the sensations that an individual feels.

Abstract P. Hed. (2011) What is health for men? Bachelor thesis. Gävle: University of Gävle, Faculty of health and occupational studies; 2011.

Payday loans are becoming a challenge of increasing gravity for society. Statistics show that the number of young adults with financial issues related to such loans has been growing over the past few years. Despite efforts to halt this trend, little is changing. Government mandated warning labels in commercials are typically used to inform about the risks associated with the consumption of certain goods and services, such as alcohol and tobacco. Despite issues related to payday loans, there is currently no legislation in Sweden mandating the inclusion of warnings in marketing of such loans.