Introduction The genetic skin disease epidermolytic ichtyosis is caused by mutations in either keratin gene 1 or 10 and leads to blisters and hyperkeratosis of the epidermis. At cellular level the disease is seen as aggregates in the keratin filaments. Since medicines are hard to investigate and produce mainly due to lack of reproducible model systems, there is no good treatment available for this disease today. In this article we describe how an in vitro model consisting of cells from a stable cell line transfected with expression plasmids to mimic patient cells, may be a possible alternative for screening compounds for therapies. The first step was to generate an expression plasmid required to complete the in vitro model.

Pupils learn in different ways, varied teaching is needed to encourage all pupils. Aesthetic can be a good tool in this work and dance is one of the aesthetic subjects that can be used in the education. Dance gives the pupils an awareness of their bodies and what they can express through it. The essay discusses diffrent angel of incidence of dance in school and its positive effects and examines what kinds of dance there are in the schools of Vänersborg?s municipal.

In this essay, I want to achieve an accessible and applicable entrance to Alexander Technique as a method for learning to use the body in such a way as to allow emotional expression in music. It is necessary to see the real need of Alexander Technique for the active musician, and therefore important components of music-making will be presented. These components are presented from an Alexander-perspective in order to produce a clear picture of the method of application.The prerequisite for emotional expression in music is musicians and music listeners with the ability to generate, and respond after emotional impressions. Alexander Technique provides an approach to make it easier for musicians, especially guitarists, to express emotions in a performance situation.After years of practice and obtaining musical knowledge and practical skills at the instrument, it is common that muscle tension and ingrained patterns contribute to limited expression. Muscle tensions arising from pressured situations such as auditions, competitions and concerts.

Syftet med den här uppsatsen är att undersöka hur svensklärare arbetar med och tänker kring integrering av bild som estetisk uttrycksform i svenskundervisningen. Uppsatsens undersökning baseras på semistrukturerade kvalitativa intervjuer. Resultatet i uppsatsen visade att svensklärarna ser positivt på att anlägga estetiska perspektiv på undervisningen. Lärarna påtalade att användningen och arbetet med bild som estetisk uttrycksform bidrar till att stärka den enskilde elevens självförtroende samt språkliga förmåga. Resultatet visade även att svensklärarnas arbete med bild som estetisk uttrycksform främst koncentreras till att framhäva de språkliga aspekterna.

In couples diagnosed with unexplained infertility, the woman has normal ovulatory cycles and no organic pathology, and the man has normal semen. The period during which the implantation of an embryo can occur is defined as the window of implantation (WOI). For infertile women, disturbances in the endometrium maturation are hypothesized to impair the uterine receptivity for embryo implantaition. However, there are still no methods found to predict endometrial receptivity.Hemoglobin related-proteins hypothesized to be involved in embryo implantation have been found in the endometrium in both fertile and infertile women. The aim of this study was to determine whether there were differences in the expression of hemoglobin-related proteins, hemoglobin-?, cytoglobin, fetal hemoglobin and haptoglobin in the endometrium of fertile and infertile women.

I chose to do this work because I believe that today?s industrial designprofessionals lack in their task of creating aesthetic experiences and aestheticdiversity.With my work, I want to question why the majority of today?s technical, massproducedeveryday products have such a similar design expression, andwhy alternatives are so few. Most of all, I take a critical attitude to today?sstereotypical industrial design aesthetics that I would describe as technical,masculine, and unnecessarily complex.I have designed a number of products that show alternative aesthetics in thissegment and as such I have chosen the vacuum cleaner. The idea is that mydesign will serve as an eye opener and demonstrate that there are alternativesto today?s homogeneous market.The result is three vacuum cleaners claiming three alternatives to currentofferings.

The development of quantitative, real-time PCR (qPCR) combined with the mapping of the canine genome opens new possibilities in veterinary medicine. This method provides a quick and accurate quantification of the expression of a specific gene at a given point in time and thereby also information of how the gene expression for a certain protein is influenced by various conditions and diseases. One possible area of application is identifying bio markers for cancer. Recently the protein serglycin (the core protein of an intracellular proteoglycan) was found to act as a selective marker for the disease acute myeloid leukemia in humans (Niemann et al, 2007). Serglycin is produced by most hematopoietic cells, although mast cells account for the largest amount of serglycin.

The aim of   the study has been to examine the duality that I seemed to find in Karin   Broos works, primarily on the basis of her renditions of nature. The   objective is to study the duality on various plans and to examine which   traces of Intertextuality that may exist.In the study of the duality   I have taken note of how nature is presented in terms of style and form, as   well as that I have seeked cultural references pictorial and symbolic. I have   also examined the images with reference to Intertextuality. The following   questions has been applied during the work:  How is nature produced in the paintings?  What place occupies nature in relation to the people, in the works?  What is being communicated by nature's participation in the works?As a method, and as a   tool for analysis and interpretation of selected works, I have chosen to use   Panofskys iconological interpretative method. As a guide to seek relations of   intertextuality the theories of  Julia   Kristeva has been useful, which  includes thoughts  that new images are created or re-created   in relation to other images all the time and in new contexts.As a result of the   study I have found some kind of expression of balance, though it did not   seemed to look that way from the beginning.

The focus of this essay is to investigate if there lies a difference between graffiti art that is placed in the public spaces and graffiti art that is sited in an institutional art setting; in this essay exemplified in a gallery space. My thesis is that graffiti art derives a great deal of its meaning and substance from its situation consequently making a change of cultural context also a change of connotation and understanding of the graffiti art itself.  Meaning that graffiti art situated in a communal space is different from graffiti art situated in the gallery space. They share Aesthetic expression but their connotations differ; i.e. one being illegal and the other permissible making their meanings dissimilar. I have used a comparison between site-specific art and graffiti art to further strengthen my thesis concerning the importance of understanding how a change of context critically changes the substance of graffiti art..

The goal of this paper is to analyze the influence of the EU on Turkish democracy. In order to achieve this aim, the paper concentrates on three areas, as representative institutions, opposition parties and freedom of expression. The impact of the EU on Turkey has been more explicit during the last decades. In particular since 1999 when the country became a candidate for membership, and that will eventually lead to Turkey joining the European Union. Thereby this paper will examine the demands EU set up for the country and how Turkey accomplishes these criteria.

The goal of this paper is to analyze the influence of the EU on Turkish democracy. In order to achieve this aim, the paper concentrates on three areas, as representative institutions, opposition parties and freedom of expression. The impact of the EU on Turkey has been more explicit during the last decades. In particular since 1999 when the country became a candidate for membership, and that will eventually lead to Turkey joining the European Union. Thereby this paper will examine the demands EU set up for the country and how Turkey accomplishes these criteria.

The aim of this study is to examine views of picture books for children that reviewers in Swedish daily press express in their reviews in 2009 and 2010. The following questions were posed in the study: Are picture book reviews based on pedagogical criteria and/or aesthetic/literary criteria? Are picture books reviewed from an adult perspective and/or from a child perspective? Which elements of positive and negative criticism are to be found in picture book reviews? This qualitative study is based on 45 reviews of picture books in Swedish daily press. The theoretical approach is developed from four ways of looking at children literature that professor Maria Nikolajeva has compiled. The method used is idea analysis, which is a form of text-analysis.

I have always been told that form follows function. But does it have to be that way? I decided to see it  from another angle.Kinesics is a term form non verbal komunication. In my thesis project I have been working with body language in furniture.  I believe that furniture, just like us, has an expression and a character. We often tend to desccribe furniture with the same words as we describe people, for example: "A relaxed chair" or "a cocky table".

Borderlands. A study of the aesthetic-practical environment, its pedagogical and therapeutical properties based on the outline of two practices/institutions: the workshops at Hagastiftelsen and the bookbindery at the Kristofferschool. The perspective on education, pedagogy and therapy taken is an existential one where the main aims of an educational-therapeutic intervention is to support biographical development and integrity. In the process action research in my own bookbinding workshop as well as hermeneutic research at the workshops at Hagastiftelsen where adults with autism and other neuropsychological disorders work have been the sources of primary empirical data. Secondary sources are patient-histories written by Oliver Sacks as well as autobiographical narratives of some adults with autism.

AbstractAim: The purpose of this thesis is to research how women think about fashion in relation to their self and to others. Can clothes be an expression of who we are who we want to be and how we look at others? What are the main characteristics in this type of communication and what kind of information can be distributed using this tool?Method/Material: InterviewsMain results: Clothes can work as a tool to show who we are and what we are, mainly on short term. We use clothes for different purposes, sometimes we what to be seen and really show who we are and what we stand for and sometimes we just what to go with the flow and not be seen at all. We will always have a physical need for clothes but it is also a natural and important part of our individual expression and our identity.Keywords: Fashion, Clothes, Identity, Lifestyle.