Syntesdesign AB is an academic company that is supposed to enter the HIV drugmarket by manufacturing a "me-too"-drug with indinavir as the starting substance.Our task is to find 100 potential indinaviranalogues. Our further task is to suggesthow to perform a bondingassay to test the affinity for all these analogues. We willpresent a method, required equipment and calculated costs for the assay..

The purpose of this essay was to investigate which factors the individuals found important in the process of becoming a person with a drug-free life. The framing of the questions we had were to get the experiences, thoughts and wishes of the drug users. The survey was based on thematised qualitative interviews and focused in the personal stories of the interviewees. We interviewed four women and five men, all of which had several years of drug-abuse behind them. We found similarities and patterns and we could identify that the three most important things was the own motivation, will and that the drug-abuser had the possibility to change their social network and had the ability to find other important things in life..

This is a thesis project in the field of information technology which begins by evaluating existing food price comparison systems and subsequently aims to design an improved, web based system for said purpose. The system features interfaces for price reporting, price comparisons as well as various search and review functions. The objective is to create a system able to compete with existing price comparison systems, which requires careful selection of products that can be found in all foodstores that also represent different households; a user-friendly price reporting and price comparison interface and an efficient tool for ensuring the validity of reported prices.The designed system features a more accurate formula for calculating average prices in events where the real price is missing; a more reliable security mechanism forv alidation of reported prices and a more comprehensible interface for viewing price reports, reporting prices, reviewing stores and products in comparison with existing systems. The system does, however, suffer from some optimization issues primarily in the form of inefficient database modeling; SQL queries and JavaScript code although testing has shown that these shortcomings do not hamper overall performance to such a degree that usability is compromised. Further usability testing performed on the system with five test subjects shows that a high level of overall user-friendliness has been achieved even though some special features, such as the detailed report containing price information per product for each store need to be improved.It is not possible to say at this time whether or not the designed system will be able to compete with existing ones or if the very concept of food price comparisons per se is viable in terms of profitability and marketability.

The aim of this essay was to examine the impact that parents drug abuse have on their children´s chances and possibilities while growing up. This study is done by investigating literature written by acknowledged authors and experts in this field. The following questions were asked:How does the literature describe the influence of parent´s drug abuse on their child´s ability to develop and learn?Which factors does the literature distinguish as determining factors on the child´s ability to resist and recover, from a childhood with drug abusing parents?The result of this essay showed that having drug abusing parents constitute different types of risks when it comes to the child´s ability to develop and learn. How the child is able to cope with it´s parents drug abuse is determined by several factors such as, the situation in the family, the child´s personality and how people in the child´s surrounding react on the child´s needs..

Rapporten inleds med en beskrivning av WM-datas Network Management struktur och Reporting Management behov. Därefter följer en beskrivning av de två analys tekniker Datamining och On Line Analytical Processing (OLAP) vilka är de mest använda databasbaserade tekniker. Verktyget Tivoli Decision Support (TDS) är ett stödssystem som ska underlätta för beslutsfattare inom organisationen. TDS baseras på OLAP ? tekniken och rapporten visar avslutningsvis de möjligheter som verktyget ger avseende WM-datas Reporting Management..

This thesis aims to examine the nature of the medial compartment regarding the reporting of problems in conjunction with suburbs. Previous research on discrimination in the media shows that people living in the suburbs considers suburbs being portrayed negatively in the media. They perceive that this has a negative effect on integration which in turn increases the risk of stigmatization. This study strives to contribute to the clarification of whether medias means of reporting around this area can help in the development of problems in suburbs by examining whether there is a reflection of actual political focus in the media or if media only plays a stigmatizing role. The research method used has been quantitative content analysis, making an overview of how much space is given to the different types of reporting. The thesis concludes that the reporting examined in this study did not appear to be of a structurally discriminatory nature, even if that type of reporting occurred.

The aim of this study was to examine the experience, knowledge and attitude to mandatory reports of mistreatments amongst first line managers and assistance nurses in municipal elderly care. The following questions were at the center of the analysis: how do the different professional groups view having to report their own organization? How can various factors affect the mandatory reporting of mistreatments? What knowledge do the different professional groups have of mistreatments and mandatory reporting? A qualitative research method was used to examine these questions in the form of semi structured interviews and a small document study. The interviews were carried out with assistance nurses and first line manages in elder care, we interviewed four respondents from both professional groups. The interviews were then transcribed and coded with help of a content analysis.

This essay will focus on drug addicts and the world as they see it. The essay is based on intervjues with three men and one woman and participant observation of the three men´s social life in the surroundings of Stockholm. The informants? opinions and experiences are central as well as the observations made of them during an intensive fieldwork. The study which was of an exploring character has revealed a complex relationship between the informants and society.

This study aims to investigate development and reasons behind sustainability reporting in large Swedish companies. By examining 15 companies? environmental and sustainability reports between the years 2000 and 2008, data was collected on matters such as frequency, scope and design. Identified trends were to a large extent in line with previous studies on international development; sustainability reporting is growing in several aspects. The authors have found one major reason for this development to be increasing requirements and expectations from stakeholders and a need for companies to legitimize their actions.

The purpose of this study was to, through the life stories of four women and their experiences, thoughts and feelings according to a life in drug dependency reach an increased knowledge about how a dependency can arise, continue and be brought to an end. The question at issue were: How do a small amount of women describe and comprehend their experiences, thoughts and feelings according to their drug addiction seen through a process perspective. In order to answer that question three themes were investigated: the road into dependency, living as an addict and the road to recovery from dependency and the time that follows. The study followed a qualitative method and the theoretical approach was hermeneutic. The results were analysed through a process analyse perspective, from the view of the chosen theoretical perspectives, social constructivism, experience perspective and a psychodynamic perspective.

In recent decades, demands has emerged that the companies shall take a greater social responsibility for the impact that they have on their environment and that this impact shall be reported, which is known as Sustainability Reporting. The Sustainability Report is based on a number of general principles that ensure the content and the quality of the Sustainability Report. One of these principles is the principle of completeness. In the research, this principle seems to have been interpreted in terms of number of reported aspects and indicators, which can be a limited view where only the existence of the aspects and indicators is observed. By including the degree of the reporting in terms of full, partial and no reporting as well as a comparison between the real and the alleged reporting, our intention is to extend the principle of completeness and to develop a tool that we also apply through an empirical survey in a particular area.

Rapporten inleds med en beskrivning av WM-datas Network Management struktur och Reporting Management behov. Därefter följer en beskrivning av de två analys tekniker Datamining och On Line Analytical Processing (OLAP) vilka är de mest använda databasbaserade tekniker. Verktyget Tivoli Decision Support (TDS) är ett stödssystem som ska underlätta för beslutsfattare inom organisationen. TDS baseras på OLAP ? tekniken och rapporten visar avslutningsvis de möjligheter som verktyget ger avseende WM-datas Reporting Management..

Transdermal drug delivery, besides painfulinjections with syringes, has long been associatedwith small size particle pharmaceuticals, which candiffuse through the skin. This method of drugadministration has only been applicable on a smallnumber of drugs, where active molecules are smalland delivery time should or can be long.Other drug delivery options are oral administrationand injection with hypodermic needles (ordinaryhospital syringes). In oral administration thestomach and liver tend to dissolve the drug and theeffect becomes more difficult to anticipate, anddrug delivery rates difficult to control. Hypodermicneedles are used as a mean of drug injectiondirectly into the bloodstream. This method ispainful and risks infection due to tissue damageand skin penetration.One way to get a painless non-damaging techniquewith high delivery rate that still can delivery largemolecules is to manufacture an array of microscopichollow needles and equip them with a pumping unitthat delivers the correct amount of drugs.This thesis shows the technique and possibility ofmanufacture micromachined needles using low costtechniques of Ion Track Technology (radiation ofheavy ions creates porous materials), electrolessdeposition (non-current activated wet chemistrymethod of depositing metal) and electroplating.

In recent decades, demands has emerged that the companies shall take a greater social responsibility for the impact that they have on their environment and that this impact shall be reported, which is known as Sustainability Reporting. The Sustainability Report is based on a number of general principles that ensure the content and the quality of the Sustainability Report. One of these principles is the principle of completeness. In the research, this principle seems to have been interpreted in terms of number of reported aspects and indicators, which can be a limited view where only the existence of the aspects and indicators is observed. By including the degree of the reporting in terms of full, partial and no reporting as well as a comparison between the real and the alleged reporting, our intention is to extend the principle of completeness and to develop a tool that we also apply through an empirical survey in a particular area.

This thesis discusses the Swedish drug policy and its principle of prohibition. In the world of today there is an ongoing discussion about prohibition and the concept of harm reduction. This thesis is an analysis of Swedish drug policy and an investigation as to whether the prohibition concept is in a state of decline. It tries to answer the question; is the Swedish drug policy moving away from its prohibition principle towards a harm reduction principle? The recent debate, articles, documents and earlier research has been analyzed in order to find answers to my questions.